Mesenchymal stem cell and immunosuppressive drug interactions

Transplantation

Volumn 87, Issue 12, 2009, Pages 1899-1900

  Buron, Fanny ^a   Morelon, Emmanuel ^c   Perrin, Hélène ^b   Malcus, Christophe ^a   Moulin, Françoise Touraine ^a   Héquet, Olivier ^a,b  

^a EDOUARD HERRIOT HOSPITAL   (France)

^b INSERM   (France)

^c Hopital Edouard Herriot ^*

Author keywords

[No Author keywords available]

Indexed keywords

CALCINEURIN INHIBITOR; CYCLOSPORIN A; GAMMA INTERFERON; IMMUNOSUPPRESSIVE AGENT; MYCOPHENOLIC ACID; RAPAMYCIN; TACROLIMUS;

CYTOKINE PRODUCTION; HEART TRANSPLANTATION; HUMAN; HUMAN CELL; IMMUNOMODULATION; INTERFERON PRODUCTION; LETTER; LYMPHOCYTE ACTIVATION; LYMPHOCYTE PROLIFERATION; MESENCHYMAL STEM CELL; MIXED LYMPHOCYTE REACTION; PRIORITY JOURNAL;

CELL DIVISION; CYCLOSPORINE; DRUG INTERACTIONS; HUMANS; IMMUNOSUPPRESSIVE AGENTS; MESENCHYMAL STEM CELLS; MITOMYCIN; MYCOPHENOLIC ACID; SIROLIMUS;

EID: 67649579014     PISSN: 00411337     EISSN: None     Source Type: Journal    
DOI: 10.1097/TP.0b013e3181a99079     Document Type: Letter

References (9)

1. TseWT,PendletonJD,BeyerWM,etal.Suppression of allogeneic T-cell proliferation by human marrow stromal cells: Implications in transplantation. Transplantation 2003; 75: 389.
2. Le Blanc K, Frassoni F, Ball L, et al. Mesenchymal stem cells for treatment of steroidresistant, severe, acute graft-versus-host disease:Aphase II study. Lancet 2008; 371: 1579.
3. Hoogduijn MJ, Crop MJ, Korevaar SS, et al. Susceptibility of human mesenchymal stem cells to tacrolimus, mycophenolate acid and rapamycin. Transplantation 2008; 86: 1283.
4. Benvenuto F, Ferrari S, Gerdoni E, et al. Human mesenchymal stem cells promote survival of T cells in a quiescent state.StemCells 2007; 25: 1753.
5. Krampera M, Cosmi L, Angeli R, et al. Role of the IFN-γ in the immunomodulatory activity of human mesenchymal stem cells. Stem Cells 2006; 24: 386.
6. Ren G, Zhang L, Zhao X, et al. Mesenchymal stem cell-mediated immunosuppression occurs via concerted action of chemokines and nitric oxide. Cell Stem Cell 2008; 2: 141.
7. Zhang W, Qin C, Zhou ZM. Mesenchymal stem cells modulate immune responses combined with cyclosporine in a rat transplantation model. Transplant Proc 2007; 39: 3404.
8. Inoue S, Popp FC, Koehl GE, et al. Immunomodulatory effects of mesenchymal stem cells in a rat organ transplant model. Transplantation 2006; 81: 1589.
9. Popp FC, Eggenhofer E, Renner P, et al. Mesenchymal stem cells can induce longterm acceptance of solid organ allografts in synergy with low-dose mycophenolate. Transplant Immunol 2008; 20: 55.