Distinct C-terminus of the B subunit of factor XIII in a population-associated major phenotype: The first case of complete allele-specific alternative splicing products in the coagulation and fibrinolytic systems

Journal of Thrombosis and Haemostasis

Volumn 7, Issue 7, 2009, Pages 1084-1091

  Iwata, H ^a   Kitano, T ^a,d   Umetsu, K ^a   Yuasa, I ^b   Yamazaki, K ^a   Kemkes matthes, B ^c   Ichinose, Akitada ^a  

^a YAMAGATA UNIVERSITY   (Japan)

^b TOTTORI UNIVERSITY   (Japan)

^c UNIVERSITY HOSPITAL GIESSEN   (Germany)

^d IBARAKI UNIVERSITY   (Japan)

Author keywords

Alternative splicing; Complete allele specificity; Isoelectric point; Matrix assisted laser desorption ionization time of flight mass spectrometry; Pheno genotype; Protein heterogeneity

Indexed keywords

ADENINE; ARGININE; BLOOD CLOTTING FACTOR 13B; CYTOSINE; GLUTAMINE; GUANINE; HISTIDINE; ISOPROTEIN; THYMINE; VALINE;

ALTERNATIVE RNA SPLICING; AMINO ACID SUBSTITUTION; ARTICLE; BLOOD CLOTTING; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; DINUCLEOTIDE REPEAT; DISEASE PREDISPOSITION; EXON; FIBRINOLYSIS; GENE FREQUENCY; GENE SEQUENCE; HUMAN; HUMAN CELL; INTRON; ISOELECTRIC POINT; LIVER CELL; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; NORMAL HUMAN; NUCLEIC ACID BASE SUBSTITUTION; NUCLEOTIDE SEQUENCE; PHENOTYPIC VARIATION; POPULATION GENETICS; PRIORITY JOURNAL; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ALLELES; ALTERNATIVE SPLICING; AMINO ACID SEQUENCE; BASE SEQUENCE; BLOOD COAGULATION; FACTOR XIII; FIBRINOLYSIS; GENETICS, POPULATION; HUMANS; MOLECULAR SEQUENCE DATA; PHENOTYPE; POLYMERASE CHAIN REACTION; POLYMORPHISM, RESTRICTION FRAGMENT LENGTH; RNA, MESSENGER; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION;

EID: 67649569501     PISSN: 15387933     EISSN: 15387836     Source Type: Journal    
DOI: 10.1111/j.1538-7836.2009.03443.x     Document Type: Article

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