A novel operant conflict procedure using incrementing shock intensities to assess the anxiolytic and anxiogenic effects of drugs

Behavioural Pharmacology

Volumn 20, Issue 3, 2009, Pages 226-236

  Evenden, John ^a,b   Ross, Laurie ^a   Jonak, Gerald ^a   Zhou, Jin ^a  

^a ASTRAZENECA   (United Kingdom)

^b WiltonLogic   (United States)

Author keywords

Benzodiazepines; Flumazenil; Operant behavior; Punished responding; Rat; Yohimbine

Indexed keywords

4 AMINOBUTYRIC ACID A RECEPTOR STIMULATING AGENT; AMPHETAMINE; ANXIOLYTIC AGENT; ARIPIPRAZOLE; BENZODIAZEPINE; CHLORDIAZEPOXIDE; DIAZEPAM; FLUMAZENIL; MK 0343; TP 003; TPA 023; UNCLASSIFIED DRUG; YOHIMBINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONFLICT; CONTROLLED STUDY; DOSE TIME EFFECT RELATION; DRUG DOSE COMPARISON; DRUG TOLERANCE; ELECTRIC SHOCK; INSTRUMENTAL CONDITIONING; MALE; NONHUMAN; PUNISHMENT; RAT; REBOUND; RESPONSE TIME; SEDATION; SHOCK; WITHDRAWAL SYNDROME;

ANIMALS; ANTI-ANXIETY AGENTS; ANXIETY; BENZODIAZEPINES; CHLORDIAZEPOXIDE; CONDITIONING, OPERANT; CONFLICT (PSYCHOLOGY); DEXTROAMPHETAMINE; DIAZEPAM; ELECTROSHOCK; FLUMAZENIL; MALE; PIPERAZINES; PUNISHMENT; PYRIDAZINES; QUINOLONES; RATS; RATS, SPRAGUE-DAWLEY; TRIAZOLES; YOHIMBINE;

EID: 67649562907     PISSN: 09558810     EISSN: None     Source Type: Journal    
DOI: 10.1097/FBP.0b013e32832a8110     Document Type: Article

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