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Volumn 33, Issue SUPPL. 2, 2009, Pages

Location, location, location: The CNS sites of leptin action dictate its regulation of homeostatic and hedonic pathways

Author keywords

Dopamine; Energy balance; Hypothalamus; Leptin

Indexed keywords

COCAINE AND AMPHETAMINE REGULATED TRANSCRIPT PEPTIDE; DOPAMINE; LEPTIN; LEPTIN RECEPTOR; PROOPIOMELANOCORTIN;

EID: 67649557384     PISSN: 03070565     EISSN: 14765497     Source Type: Journal    
DOI: 10.1038/ijo.2009.66     Document Type: Conference Paper
Times cited : (14)

References (28)
  • 2
    • 0030028959 scopus 로고    scopus 로고
    • Phenotypes of mouse diabetes and rat fatty due to mutations in the OB (leptin) receptor
    • Chua Jr SC, Chung WK, Wu-Peng XS, Zhang Y, Liu SM, Tartaglia L et al. Phenotypes of mouse diabetes and rat fatty due to mutations in the OB (leptin) receptor. Science 1996; 271: 994-996.
    • (1996) Science , vol.271 , pp. 994-996
    • Chua Jr, S.C.1    Chung, W.K.2    Wu-Peng, X.S.3    Zhang, Y.4    Liu, S.M.5    Tartaglia, L.6
  • 4
    • 27744436291 scopus 로고    scopus 로고
    • Identifying hypothalamic pathways controlling food intake, body weight, and glucose homeostasis
    • Elmquist JK, Coppari R, Balthasar N, Ichinose M, Lowell BB. Identifying hypothalamic pathways controlling food intake, body weight, and glucose homeostasis. J Comp Neurol 2005; 493: 63-71.
    • (2005) J Comp Neurol , vol.493 , pp. 63-71
    • Elmquist, J.K.1    Coppari, R.2    Balthasar, N.3    Ichinose, M.4    Lowell, B.B.5
  • 5
    • 17844401704 scopus 로고    scopus 로고
    • Anatomy and regulation of the central melanocortin system
    • Cone RD. Anatomy and regulation of the central melanocortin system. Nat Neurosci 2005; 8: 571-578.
    • (2005) Nat Neurosci , vol.8 , pp. 571-578
    • Cone, R.D.1
  • 6
    • 30644473109 scopus 로고    scopus 로고
    • Leptin directly activates SF1 neurons in the VMH, and this action by leptin is required for normal body-weight homeostasis
    • Dhillon H, Zigman JM, Ye C, Lee CE, McGovern RA, Tang V et al. Leptin directly activates SF1 neurons in the VMH, and this action by leptin is required for normal body-weight homeostasis. Neuron 2006; 49: 191-203.
    • (2006) Neuron , vol.49 , pp. 191-203
    • Dhillon, H.1    Zigman, J.M.2    Ye, C.3    Lee, C.E.4    McGovern, R.A.5    Tang, V.6
  • 7
    • 54349113070 scopus 로고    scopus 로고
    • Selective inactivation of Socs3 in SF1 neurons improves glucose homeostasis without affecting body weight
    • Zhang R, Dhillon H, Yin H, Yoshimura A, Lowell BB, Maratos-Flier E et al. Selective inactivation of Socs3 in SF1 neurons improves glucose homeostasis without affecting body weight. Endocrinology 2008; 149: 5654-5661.
    • (2008) Endocrinology , vol.149 , pp. 5654-5661
    • Zhang, R.1    Dhillon, H.2    Yin, H.3    Yoshimura, A.4    Lowell, B.B.5    Maratos-Flier, E.6
  • 8
    • 42449086900 scopus 로고    scopus 로고
    • Selective loss of leptin receptors in the ventromedial hypotha-lamic nucleus results in increased adiposity and a metabolic syndrome
    • Bingham NC, Anderson KK, Reuter AL, Stallings NR, Parker KL. Selective loss of leptin receptors in the ventromedial hypotha-lamic nucleus results in increased adiposity and a metabolic syndrome. Endocrinology 2008; 149: 2138-2148.
    • (2008) Endocrinology , vol.149 , pp. 2138-2148
    • Bingham, N.C.1    Anderson, K.K.2    Reuter, A.L.3    Stallings, N.R.4    Parker, K.L.5
  • 10
    • 34250305087 scopus 로고    scopus 로고
    • Effects of glucose and insulin on glucokinase activity in rat hypothalamus
    • Sanz C, Roncero I, Vazquez P, Navas MA, Blazquez E. Effects of glucose and insulin on glucokinase activity in rat hypothalamus. J Endocrinol 2007; 193: 259-267.
    • (2007) J Endocrinol , vol.193 , pp. 259-267
    • Sanz, C.1    Roncero, I.2    Vazquez, P.3    Navas, M.A.4    Blazquez, E.5
  • 11
    • 0032971214 scopus 로고    scopus 로고
    • Microinjection of leptin into the ventromedial hypothalamus increases glucose uptake in peripheral tissues in rats
    • Minokoshi Y, Haque MS, Shimazu T. Microinjection of leptin into the ventromedial hypothalamus increases glucose uptake in peripheral tissues in rats. Diabetes 1999; 48: 287-291.
    • (1999) Diabetes , vol.48 , pp. 287-291
    • Minokoshi, Y.1    Haque, M.S.2    Shimazu, T.3
  • 12
    • 27744457512 scopus 로고    scopus 로고
    • Topographic mapping of VMH→arcuate nucleus microcircuits and their reorganization by fasting
    • Sternson SM, Shepherd GM, Friedman JM. Topographic mapping of VMH→arcuate nucleus microcircuits and their reorganization by fasting. Nat Neurosci 2005; 8: 1356-1363.
    • (2005) Nat Neurosci , vol.8 , pp. 1356-1363
    • Sternson, S.M.1    Shepherd, G.M.2    Friedman, J.M.3
  • 13
    • 33745142241 scopus 로고    scopus 로고
    • Characterization of leptinresponsive neurons in the caudal brainstem
    • Ellacott KL, Halatchev IG, Cone RD. Characterization of leptinresponsive neurons in the caudal brainstem. Endocrinology 2006; 147: 3190-3195.
    • (2006) Endocrinology , vol.147 , pp. 3190-3195
    • Ellacott, K.L.1    Halatchev, I.G.2    Cone, R.D.3
  • 14
    • 34249785695 scopus 로고    scopus 로고
    • Leptin and the control of food intake: Neurons in the nucleus of the solitary tract are activated by both gastric distension and leptin
    • Huo L, Maeng L, Bjorbaek C, Grill HJ. Leptin and the control of food intake: neurons in the nucleus of the solitary tract are activated by both gastric distension and leptin. Endocrinology 2007; 148: 2189-2197.
    • (2007) Endocrinology , vol.148 , pp. 2189-2197
    • Huo, L.1    Maeng, L.2    Bjorbaek, C.3    Grill, H.J.4
  • 15
    • 33750300106 scopus 로고    scopus 로고
    • Modulation of vagal afferent excitation and reduction of food intake by leptin and cholecys-tokinin
    • Peters JH, Simasko SM, Ritter RC. Modulation of vagal afferent excitation and reduction of food intake by leptin and cholecys-tokinin. Physiol Behav 2006; 89: 477-485.
    • (2006) Physiol Behav , vol.89 , pp. 477-485
    • Peters, J.H.1    Simasko, S.M.2    Ritter, R.C.3
  • 16
    • 0037057816 scopus 로고    scopus 로고
    • Brain reward circuitry: Insights from unsensed incentives
    • Wise RA. Brain reward circuitry: insights from unsensed incentives. Neuron 2002; 36: 229-240.
    • (2002) Neuron , vol.36 , pp. 229-240
    • Wise, R.A.1
  • 18
    • 34347325204 scopus 로고    scopus 로고
    • Decreased vesicular somatodendritic dopamine stores in leptin-deficient mice
    • Roseberry AG, Painter T, Mark GP, Williams JT. Decreased vesicular somatodendritic dopamine stores in leptin-deficient mice. J Neurosci 2007; 27: 7021-7027.
    • (2007) J Neurosci , vol.27 , pp. 7021-7027
    • Roseberry, A.G.1    Painter, T.2    Mark, G.P.3    Williams, J.T.4
  • 19
    • 0037458468 scopus 로고    scopus 로고
    • Expression of receptors for insulin and leptin in the ventral tegmental area/substantia nigra (VTA/SN) of the rat
    • Figlewicz DP, Evans SB, Murphy J, Hoen M, Baskin DG. Expression of receptors for insulin and leptin in the ventral tegmental area/substantia nigra (VTA/SN) of the rat. Brain Res 2003; 964: 107-115.
    • (2003) Brain Res , vol.964 , pp. 107-115
    • Figlewicz, D.P.1    Evans, S.B.2    Murphy, J.3    Hoen, M.4    Baskin, D.G.5
  • 20
    • 33748540764 scopus 로고    scopus 로고
    • Leptin receptor signaling in midbrain dopamine neurons regulates feeding
    • Hommel JD, Trinko R, Sears RM, Georgescu D, Liu ZW, Gao XB et al. Leptin receptor signaling in midbrain dopamine neurons regulates feeding. Neuron 2006; 51: 801-810.
    • (2006) Neuron , vol.51 , pp. 801-810
    • Hommel, J.D.1    Trinko, R.2    Sears, R.M.3    Georgescu, D.4    Liu, Z.W.5    Gao, X.B.6
  • 21
    • 0011754160 scopus 로고
    • Adipsia and aphagia in rats after lateral subthalamic lesions
    • Morrison SD, Mayer J. Adipsia and aphagia in rats after lateral subthalamic lesions. Am J Physiol 1957; 191: 248-254.
    • (1957) Am J Physiol , vol.191 , pp. 248-254
    • Morrison, S.D.1    Mayer, J.2
  • 22
    • 0038173575 scopus 로고    scopus 로고
    • Lateral hypothalamic neuropeptides in reward and drug addiction
    • DiLeone RJ, Georgescu D, Nestler EJ. Lateral hypothalamic neuropeptides in reward and drug addiction. Life Sci 2003; 73: 759-768.
    • (2003) Life Sci , vol.73 , pp. 759-768
    • DiLeone, R.J.1    Georgescu, D.2    Nestler, E.J.3
  • 23
    • 20144362544 scopus 로고    scopus 로고
    • The hypothalamic neuropeptide melanin-concentrating hormone acts in the nucleus accumbens to modulate feeding behavior and forced-swim performance
    • Georgescu D, Sears RM, Hommel JD, Barrot M, Bolanos CA, Marsh DJ et al. The hypothalamic neuropeptide melanin-concentrating hormone acts in the nucleus accumbens to modulate feeding behavior and forced-swim performance. J Neurosci 2005; 25: 2933-2940.
    • (2005) J Neurosci , vol.25 , pp. 2933-2940
    • Georgescu, D.1    Sears, R.M.2    Hommel, J.D.3    Barrot, M.4    Bolanos, C.A.5    Marsh, D.J.6
  • 24
    • 0037659189 scopus 로고    scopus 로고
    • Involvement of the lateral hypothalamic peptide orexin in morphine dependence and withdrawal
    • Georgescu D, Zachariou V, Barrot M, Mieda M, Willie JT, Eisch AJ et al. Involvement of the lateral hypothalamic peptide orexin in morphine dependence and withdrawal. J Neurosci 2003; 23: 3106-3111.
    • (2003) J Neurosci , vol.23 , pp. 3106-3111
    • Georgescu, D.1    Zachariou, V.2    Barrot, M.3    Mieda, M.4    Willie, J.T.5    Eisch, A.J.6
  • 25
    • 35348824334 scopus 로고    scopus 로고
    • Orexin signaling in the ventral tegmental area is required for high-fat appetite induced by opioid stimulation of the nucleus accumbens
    • Zheng H, Patterson LM, Berthoud HR. Orexin signaling in the ventral tegmental area is required for high-fat appetite induced by opioid stimulation of the nucleus accumbens. J Neurosci 2007; 27: 11075-11082.
    • (2007) J Neurosci , vol.27 , pp. 11075-11082
    • Zheng, H.1    Patterson, L.M.2    Berthoud, H.R.3
  • 26
    • 0036341292 scopus 로고    scopus 로고
    • Antidepressant, anxiolytic and anorectic effects of a melanin-concentrating hormone-1 receptor antagonist
    • Borowsky B, Durkin MM, Ogozalek K, Marzabadi MR, DeLeon J, Lagu B et al. Antidepressant, anxiolytic and anorectic effects of a melanin-concentrating hormone-1 receptor antagonist. Nat Med 2002; 8: 825-830.
    • (2002) Nat Med , vol.8 , pp. 825-830
    • Borowsky, B.1    Durkin, M.M.2    Ogozalek, K.3    Marzabadi, M.R.4    DeLeon, J.5    Lagu, B.6
  • 27
    • 0035055943 scopus 로고    scopus 로고
    • SB-334867, a selective orexin-1 receptor antagonist, enhances behavioural satiety and blocks the hyperphagic effect of orexin-A in rats
    • Rodgers RJ, Halford JC, Nunes de Souza RL, Canto de Souza AL, Piper DC, Arch JR et al. SB-334867, a selective orexin-1 receptor antagonist, enhances behavioural satiety and blocks the hyperphagic effect of orexin-A in rats. Eur J Neurosci 2001; 13: 1444-1452.
    • (2001) Eur J Neurosci , vol.13 , pp. 1444-1452
    • Rodgers, R.J.1    Halford, J.C.2    Nunes de Souza, R.L.3    Canto de Souza, A.L.4    Piper, D.C.5    Arch, J.R.6
  • 28
    • 33847121297 scopus 로고    scopus 로고
    • The neural circuit of orexin (hypocretin): Maintaining sleep and wakefulness
    • Sakurai T. The neural circuit of orexin (hypocretin): maintaining sleep and wakefulness. Nat Rev 2007; 8: 171-181.
    • (2007) Nat Rev , vol.8 , pp. 171-181
    • Sakurai, T.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.