Human leukocyte antigen-related risk factors for toxic epidermal necrosis

Pediatric Infectious Disease Journal

Volumn 28, Issue 6, 2009, Pages 552-

  Kemen, Christoph ^a   Lemke, Joachim ^a   Hoeger, Peter H ^a   Beckmann, Christoph ^b   Hennenberger, Axel ^b   Detjen, Anne ^d   Magdorf, Klaus ^c  

^a Catholic Children's Hospital Wilhelmstift   (Germany)

^b Catholic Children's Hospital Wilhelmstift   (Germany)

^c CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^d Chest Hospital Heckeshorn   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ALLOPURINOL; BIOBRANE; ETHAMBUTOL; HLA ANTIGEN; IMMUNOGLOBULIN; ISONIAZID; PYRAZINAMIDE; RASBURICASE; RIFAMPICIN;

ADD ON THERAPY; ALLELE; CASE REPORT; CHILD; CLINICAL FEATURE; DRUG WITHDRAWAL; EPIDERMIS; FEMALE; FEVER; GENETIC PREDISPOSITION; GOUT; HUMAN; HUMAN TISSUE; HYPERURICEMIA; LETTER; PRIORITY JOURNAL; RISK FACTOR; SCHOOL CHILD; SIDE EFFECT; SKIN MANIFESTATION; TOXIC EPIDERMAL NECROLYSIS; TUBERCULOSIS; URIC ACID BLOOD LEVEL;

EID: 67649518992     PISSN: 08913668     EISSN: 15320987     Source Type: Journal    
DOI: 10.1097/INF.0b013e31819f3610     Document Type: Letter

References (5)

1. Chung WH, Hung SI, Yang JY, et al. Granulysin is a key mediator for disseminated keratinocyte death in Stevens-Johnson syndrome and toxic epidermal necrolysis. Nat Med. 2008;14:1343- 1350.
2. Halevy S, Ghislain PD, Mockenhaupt M, et al. Allopurinol is the most common cause of Stevens-Johnson syndrome and toxic epidermal necrolysis in Europe and Israel. J Am Acad Dermatol. 2008; 58:25-32.
3. Chung WH, Hung SI, Chen YT. Human leukocyte antigens and drug hypersensitivity. Curr Opin Allergy Clin Immunol. 2007;7:317-323.
4. Hung SI, Chung WH, Liou LB, et al. HLA-B*5801 allele as a genetic marker for severe cutaneous adverse reactions caused by allopurinol. Proc Natl Acad Sci USA. 2005; 102:4134-4139.
5. World Health Organization (WHO). Treatment of Tuberculosis: Guidelines For National Programmes. 3rd ed. Geneva, Switzerland: World Health Organization; 2003:WHO/CDS/TB/ 2003.313.