Peptide mimics of two pneumococcal capsular polysaccharide serotypes (6B and 9V) protect mice from a lethal challenge with Streptococcus pneumoniae

European Journal of Immunology

Volumn 39, Issue 6, 2009, Pages 1527-1535

  Smith, Claire M ^a   Lo Passo, Carla ^b   Scuderi, Angela ^b   Kolberg, Jan ^c   Baxendale, Helen ^d   Goldblatt, David ^d   Oggioni, Marco R ^e   Felici, Franco ^b,f   Andrew, Peter W ^a  

^a UNIVERSITY OF LEICESTER   (United Kingdom)

^b UNIVERSITY OF MESSINA   (Italy)

^c NORWEGIAN INSTITUTE OF PUBLIC HEALTH   (Norway)

^d UNIVERSITY COLLEGE LONDON   (United Kingdom)

^e UNIVERSITY OF SIENA   (Italy)

^f Dipartimento STAT   (Italy)

Author keywords

Mimotope; Peptide; Polysaccharide; Streptococcus pneumoniae; Vaccine

Indexed keywords

HEMOCYANIN; IMMUNOGLOBULIN G1 ANTIBODY; MONOCLONAL ANTIBODY; PEPTIDE VACCINE; PNEUMOCOCCUS VACCINE; BACTERIAL POLYSACCHARIDE; IMMUNOGLOBULIN G; PEPTIDE; PEPTIDE LIBRARY;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY SPECIFICITY; ANTIGEN SPECIFICITY; ARTICLE; BACTERIOPHAGE; CONTROLLED STUDY; DRUG SCREENING; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; HUMAN; MOUSE; NONHUMAN; PNEUMOCOCCAL INFECTION; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN EXPRESSION; SEROTYPE; STREPTOCOCCUS PNEUMONIAE; VACCINE PRODUCTION; AMINO ACID SEQUENCE; ANIMAL; ANTIGEN ANTIBODY REACTION; BACTERIAL MEMBRANE; BLOOD; IMMUNOLOGY; KAPLAN MEIER METHOD; MOLECULAR GENETICS; MOLECULAR MIMICRY; MOUSE STRAIN; VACCINATION;

AMINO ACID SEQUENCE; ANIMALS; ANTIBODIES, MONOCLONAL; ANTIGEN-ANTIBODY REACTIONS; BACTERIAL CAPSULES; FEMALE; HUMANS; IMMUNOGLOBULIN G; KAPLAN-MEIERS ESTIMATE; MICE; MICE, INBRED STRAINS; MOLECULAR MIMICRY; MOLECULAR SEQUENCE DATA; PEPTIDE LIBRARY; PEPTIDES; PNEUMOCOCCAL INFECTIONS; PNEUMOCOCCAL VACCINES; POLYSACCHARIDES, BACTERIAL; STREPTOCOCCUS PNEUMONIAE; VACCINATION;

EID: 67649515770     PISSN: 00142980     EISSN: 15214141     Source Type: Journal    
DOI: 10.1002/eji.200839091     Document Type: Article

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