High prevalence of 'Borrelia-like' organisms in skin biopsies of sarcoidosis patients from Western Austria

Journal of Cutaneous Pathology

Volumn 36, Issue 12, 2009, Pages 1262-1268

  Derler, Anna Maria ^a   Eisendle, Klaus ^a   Baltaci, Mehmet ^a   Obermoser, Gerlinde ^a   Zelger, Bernhard ^a  

^a INNSBRUCK MEDICAL UNIVERSITY   (Austria)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIUM ANTIBODY; POLYCLONAL ANTIBODY;

ADULT; AGED; ARTICLE; AUSTRIA; BACTERIUM DETECTION; BORRELIA; CLINICAL ARTICLE; CONTROLLED STUDY; ERYTHEMA CHRONICUM MIGRANS; FALSE POSITIVE RESULT; FEMALE; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MALE; MICROSCOPY; PATHOGENESIS; POLYMERASE CHAIN REACTION; PREVALENCE; RETROSPECTIVE STUDY; SARCOIDOSIS; SKIN BIOPSY; SKIN GRANULOMA; SPIROCHETE;

ADOLESCENT; ADULT; AGED; AUSTRIA; BIOPSY; BORRELIA; BORRELIA INFECTIONS; CHILD; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; MALE; MIDDLE AGED; POLYMERASE CHAIN REACTION; PREVALENCE; RETROSPECTIVE STUDIES; SARCOIDOSIS; SKIN DISEASES; YOUNG ADULT;

EID: 67649509970     PISSN: 03036987     EISSN: 16000560     Source Type: Journal    
DOI: 10.1111/j.1600-0560.2009.01271.x     Document Type: Article

References (45)

1. Reich JM. What is sarcoidosis? Chest 2003 124 (1 367.
2. Thomas KW, Hunnighake GW. Sarcoidosis. JAMA 2003 289 (24 3300.
3. ACCESS Research group. Design of a case control etiology study of sarcoidosis (ACCESS). J Clin Epidemiol 1999 52 : 1173.
4. Rybicki BA, Major M, Popovich J, et al. Racial differences in sarcoidosis incidence: a 5-year study in a health maintenance organization. Am J Epidemiol 1997 145 : 234.
5. Milman N, Selroos O. Pulmonary sarcoidosis in the nordic countries 1950-1982: epidemiology and clinical picture. Sarcoidosis 1990 7 (1 50.
6. Eklund A, Rizzato G. Skin manifestations in sarcoidosis. Eur Respir J Monogr 2005 10 : 150.
7. Mana J, Marcoval J, Graells J, Salazar A, Peyri J, Pujol R. Cutaneous involvement in sarcoidosis: relationship to systemic disease. Arch Dermatol 1997 133 : 882.
8. Mangas C, Fernandez-Figueras MT, Fite E, et al. Clinical spectrum and histopathological analysis of 32 cases of specific cutaneous sarcoidosis. J Cutan Pathol 2006 33 : 772.
9. Umbert P, Winkelmann RK. Granuloma annulare and sarcoidosis. Br J Dermatol 1977 97 (5 481.
10. Harrison P, Shuster S. Granuloma annulare and sarcoidosis. Br J Dermatol 1979 100 (2 231.
11. Kato H, Fujieda Y, Kitajima Y, Yaoita H. A case of granuloma annulare and sarcoidosis. J Dermatol 1985 12 (1 63.
12. Ehrich EW, Mc Guire JL, Kim YH. Association of granuloma annulare with sarcoidosis. Arch Dermatol 1992 128 (6) 855.
13. Lupton JR, Figueroa P, Berberian BJ, Sulica VI. Can granuloma annulare evolve into cutaneous sarcoidosis? Cutis 2000 66 (5 390.
14. Ziemer M, Grabner T, Eisendle K, Baltaci M, Zelger B. Granuloma annulare - a manifestation of infection with borrelia? J Cutan Pathol 2008 35 : 1050.
15. Eisendle K, Grabner T, Zelger B. Focus floating microscopy, gold standard for cutaneous borreliosis? Am J Clin Pathol 2007 127 : 213.
16. Eisendle K, Grabner T, Zelger B. Morphaea: a manifestation of infection with Borrelia species? Br J Dermatol 2007 157 : 1189 Epub 2007 Oct 17.
17. Newman LS, Rose CS, Maier LA. Sarcoidosis. N Engl J Med 1997 336 : 1224.
18. Shetty A, Gedalia A. Sarcoidosis. http//www.emedicine.com/ped/topic2043. htm. Accessed June 9, 2006.
19. Fite E, Fernandez-Figueras MT, Prats R, et al. High prevalence of Mycobacterium tuberculosis DNA in biopsies from sarcoidosis patients from Catalonia, Spain. Respiration 2006 73 (1 20.
20. Gazouli M, Ikonmopoulos J, Trigidou R, et al. Assessment of mycobacterial, propionibacterial and human herpesvirus DNA in tissues of Greek patients with sarcoidosis. J Clin Microbiol 2002 40 : 3060.
21. Fredericks DN, Relman DA. Infectious agents and the etiology of chronic idiopathic diseases. Curr Clin Top Infect Dis 1998 18 : 180.
22. Ishihara M, Ohno S, Ono H, et al. Seroprevalence of anti-Borrelia antibodies among patients with confirmed sarcoidosis in a region of Japan where Lyme borreliosis is endemic. Graefes Arch Clin Exp Ophthalmol 1998 236 (4 280.
23. McGrath DS, Goh N, Foley PJ, du Bois RM. Sarcoidosis: genes and microbes - soil or seed? Sarcoidosi Vasc Diffuse Lung Dis 2001 18 (2 149.
24. Spiegel IB, White SD, Foley JE, Drazenovich NL, Ihrke PJ, Affolter VK. A retrospective study of cutaneous equine sarcoidosis and its potential infectious aetiological agents. Vet Dermatol 2006 17 (1 51.
25. Klint H, Siboni AH. Borreliosis associated with Lofgren's syndrome. Ugeskr Laeger 2000 162 (31 4154.
26. Martens H, Zöllner B, Zissel G, Burdon D, Schlaak M, Müller-Quernheim J. Anti-Borrelia burgdorferi immunoglobulin seroprevalence in pulmonary sarcoidosis: a negative report. Eur Respir J 1997 10 (6 1356.
27. Xu Z, Ma D, Luo W, Zhu Y. Detection of Borrelia burgdorferi DNA in granulomatous tissues from patients with sarcoidosis using polymerase chain reaction in situ technique. Chin Med Sci J 1996 11 (4 220.
28. Ishihara M, Ishida T, Isogai E, et al. Detection of antibodies to Borrelia species among patients with confirmed sarcoidosis in a region where Lyme disease is nonendemic. Graefes Arch Clin Exp Ophthalmol 1996 234 (12 770.
29. Lian W, Luo W. Borrelia burgdorferi DNA in biological samples from patients with sarcoidosis using the polymerase chain reaction technique. Chin Med Sci J 1995 10 (2 93.
30. Morris JT, Longfield RN. Sarcoidosis and ELISA for Borrelia burgdorferi. South Med J 1994 87 (6 590.
31. Arcangeli G, Calabro S, Cisno F, Zambotto FM, Drigo R, Ferraresso A. Determination of antibodies to Borrelia burgdorferi in sarcoidosis. Sarcoidosis 1994 11 (1 32.
32. Chen YQ, Miao JZ, Zhang XZ. Determination of antibody of Borrelia burgdorferi in the serum of patients with sarcoidosis and its significance. Zhonghua Nei Ke Za Zhi 1994 33 (1 15.
33. Liu HG. Spirochetes in the cheilitis granulomatosa and sarcoidosis. Zhonghua Yi Xue Za Zhi 1993 73 (3 142, 189.
34. Hua B, Li QD, Wang FM, Ai CX, Luo WC. Borrelia burgdorferi infection may bet he cause of sarcoidosis. Chin Med J (Engl) 1992 105 (7 560.
35. Montemurro L, Rizzato G. Is sarcoidosis a borreliosis? Sarcoidosis 1991 8 (2 134.
36. http://www.oeghmp.at/EUCALB/. Accessed December 2, 2007.
37. Iannuzzi MC. Genetics of sarcoidosis. Semin Respir Crit Care Med 2007 28 : 15.
38. Aberer E, Duray PH. Morphology of Borrelia burgdorferi: Structural Patterns of Cultured Borreliae in Relation to Staining Methods. J Clin Microbiol 1991 29 : 764.
39. Gruntar I, Malovrh T, Murgia R, Cinco M. Conversion of Borrelia garinii cystic forms to motile spirochetes in vivo. APMIS 2001 109 (5 383.
40. Murgia R, Piazzetta C, Cinco M. Cystic forms of Borrelia burgdorferi sensu lato: induction, development, and role of RpoS. Wien Klin Wochenschr 2002 114 (13-14 574.
41. van Dam AP, Kuiper H, Vos K, et al. Different genospecies of Borrelia burgdorferi are associated with distinct clinical manifestations of Lyme borreliosis. Clin Infect Dis 1993 17 : 708.
42. Melchers W, Meis J, Rosa P, et al. Amplification of Borrelia burgdorferi DNA in skin biopsies from patients with Lyme disease. J Clin Microbiol 1991 29 : 2401.
43. Moter SE, Hofmann H, Wallich R, Simon MM, Kramer MD. Detection of Borrelia burgdorferi sensu lato in lesional skin of patients with erythema migrans and acrodermatitis chronica atrophicans by ospA-specific PCR. J Clin Microbiol 1994 32 : 2980.
44. von Stedingk LV, Olsson I, Hanson HS, Asbrink E, Hovmark A. Polymerase chain reaction for detection of Borrelia burgdorferi DNA in skin lesions of early and late Lyme borreliosis. Eur J Clin Microbiol Infect Dis 1995 14 : 1.
45. Zsikla V, Baumann M, Cathomas G. Effect of buffered formalin on amplification of DNA from paraffin wax embedded small biopsies using real-time PCR. J Clin Pathol 2004 57 : 654.