Transcript analyses of stromal cell derived factors (SDFs): SDF-2, SDF-4 and SDF-5 reveal a different pattern of expression and prognostic association in human breast cancer

International Journal of Oncology

Volumn 35, Issue 1, 2009, Pages 205-211

  Kang, Hua ^a,b   Escudero Esparza, Astrid ^a   Douglas Jones, Anthony ^a   Mansel, Robert E ^a   Jiang, Wen G ^a  

^a CARDIFF UNIVERSITY SCHOOL OF MEDICINE   (United Kingdom)

^b CAPITAL MEDICAL UNIVERSITY   (China)

Author keywords

Breast cancer; Prognosis; SDF 2; SDF 4; SDF 5; SDF2 like; Stromal cell derived factor; Survival

Indexed keywords

CHEMOKINE; STROMAL CELL DERIVED FACTOR 2; STROMAL CELL DERIVED FACTOR 2 LIKE 1; STROMAL CELL DERIVED FACTOR 4; STROMAL CELL DERIVED FACTOR 5; UNCLASSIFIED DRUG;

ARTICLE; BREAST CANCER; CANCER CELL CULTURE; CANCER MORTALITY; CANCER TISSUE; CONTROLLED STUDY; DISEASE ASSOCIATION; DISEASE FREE SURVIVAL; GENE EXPRESSION; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MAJOR CLINICAL STUDY; METASTASIS; PRIORITY JOURNAL; PROGNOSIS; PROTEIN ANALYSIS; PROTEIN EXPRESSION; TISSUE DISTRIBUTION;

BREAST NEOPLASMS; CALCIUM-BINDING PROTEINS; CELL LINE, TUMOR; CHEMOKINES, CXC; DISEASE-FREE SURVIVAL; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; GLYCOPROTEINS; HUMANS; MEMBRANE PROTEINS; NEOPLASM STAGING; PROGNOSIS; PROTEINS; RNA, MESSENGER; SURVIVAL ANALYSIS;

EID: 67649442509     PISSN: 10196439     EISSN: 17912423     Source Type: Journal    
DOI: 10.3892/ijo_00000330     Document Type: Article

References (24)

1. Nagasawa T, Kikutani H and Kishimoto T: Molecular cloning and structure of a pre-B-cell growth-stimulating factor. Proc Natl Acad Sci USA 91: 2305-2309, 1994.
2. Shirozu M, Nakano T, Inazawa J, Tashiro K, Tada H, Shinohara T and Honjo T: Structure and chromosomal localization of the human stromal cell-derived factor 1 (SDF1) gene. Genomics 28: 495-500, 1995.
3. Salcedo R, Wasserman K, Young HA, Grimm MC, Howard OM, Anver MR, Kleinman HK, Murphy WJ and Oppenheim JJ: Vascular endothelial growth factor and basic fibroblast growth factor induce expression of CXCR4 on human endothelial cells: in vivo neovascularization induced by stromal derived factor-1α. Am J Pathol 154: 1125-1135, 1999.
4. Bartolome RA, Galvez BG, Longo N, Baleux F, van Muijen GN, Sanchez-Mateos P, Arroyo AG and Teixido J: Stromal cell-derived factor-1 promotes melanoma cell invasion across basement membranes involving stimulation of membrane-type 1 matrix metalloproteinase and Rho GTPase activities. Cancer Res 64: 2534-2543, 2004.
5. Hall JM and Korach KS: Stromal cell-derived factor 1, a novel target of estrogen receptor action, mediates the mitogenic effects of estradiol in ovarian and breast cancer cells. Mol Endocrinol 17: 792-803, 2003.
6. Zeelenberg IS, Ruuls-van Stalle L and Roos E: The chemokine receptor CXCR4 is required for outgrowth of colon carcinoma micrometastases. Cancer Res 63: 3833-3839, 2003.
7. Muller A, Homey B, Soto H, Ge N, Catron D, Buchanan ME, McClanahan T, Murphy E, Yuan W, Wagner SN, et al: Involvement of chemokine receptors in breast cancer metastasis. Nature 410: 50-56, 2001.
8. Kang H, Parr C, Mansel RE and Jiang WG: Stroma-derived factor 1 (SDF-1) and the invasiveness of breast cancer cells, the clinical implications. Breast Cancer Res 7: R402-R410, 2005.
9. Kang W, Watkins G, Douglas-Jones A, Mansel RE and Jiang WG: The elevated level of CXCR4 expression is correlated with lymph node metastasis in human breast cancer. Breast 14: 360-367, 2005.
10. Kang H, Mansel RE and Jiang WG: The role of stroma-derived factor 1 (SDF-1) in the migration and invasion of breast cancer cells. Int J Oncol 26: 1429-1434, 2005.
11. Hamada T, Tashiro K, Tada H, Inazawa J, Shirozu M, Shibahara K, NakamuraT, Martina N, Nakano T and Honjo T: Isolation and characterization of a novel secretory protein, stromal cell-derived factor-2 (SDF-2) using the signal sequence trap method. Gene 176: 211-214, 1996.
12. Lam PP, Hyvarinen K, Kauppi M, Cosen-Binker L, Laitinen S, Keranen S, Gaisano HY and Olkkonen VM: A cytosolic splice variant of Cab45 interacts with Munc18b and impacts on amylase secretion by pancreatic acini. Mol Biol Cell 18: 2473-2480, 2007.
13. Shirozu M, Tada H, Tashiro K, Nakamura T, Lopez ND, Nazarea M, Hamada T, Sato T, Nakano T and Honjo T: Characterization of novel secreted and membrane proteins isolated by the signal sequence trap method. Genomics 37: 273-280, 1996.
14. Fukuda S, Sumii M, Masuda Y, Takahashi M, Koike N, Teishima J, Yasumoto H, Itamoto T, Asahara T, Dohi K and Kamiya K: Murine and human SDF2L1 is an endoplasmic reticulum stress-inducible gene and encodes a new member of the Pmt/rt protein family. Biochem Biophys Res Commun 280: 407-414, 2001.
15. 2+)-binding protein localized to the Golgi lumen. J Cell Biol 133: 257-268, 1996.
16. 2+-binding protein with six EF-hand motifs. DNA Seq 7: 217-220, 1997.
17. Grønborg M, Kristiansen TZ, Iwahori A, Chang R, Reddy R, Sato N, Molina H, Jensen ON, Hruban RH, Goggins MG, Maitra A and Pandey A: Biomarker discovery from pancreatic cancer secretome using a differential proteomic approach. Mol Cell Proteomics 5: 157-171, 2006.
18. Vendrell E, Ribas M, Valls J, Solé X, Grau M, Moreno V, Capellà G and Peinado MA: Genomic and transcriptomic prognostic factors in R0 Dukes B and C colorectal cancer patients. Int J Oncol 30: 1099-1107, 2007.
19. Nazarenko IA, Bhatnagar SK and Hohman RJ: A closed tube format for amplification and detection of DNA based on energy transfer. Nucleic Acids Res 25: 2516-2521, 1997.
20. Jiang WG, Watkins G, Douglas-Jones A, Mokbel K, Mansel RE and Fodstad O: Expression of Com-1/p8 in human breast cancer, and its relevance to clinical outcome and ER status. Int J Cancer 117: 730-737, 2005.
21. Jiang WG, Watkins G, Lane J, Douglas-Jones A, Cunnick GH, Mokbel M and Mansel RE: Prognostic value of Rho family and and rho-GDIs in breast cancer. Clin Cancer Res 9: 6432-6440, 2003.
22. Chang JT, Esumi N, Moore K, Li Y, Zhang S, Chew C, Goodman B, Rattner A, Moody S, Stetten G, Campochiaro PA and Zack DJ: Cloning and characterization of a secreted frizzled-related protein that is expressed by the retinal pigment epithelium. Hum Mol Genet 8: 575-583, 1999.
23. Rattner A, Hsieh JC, Smallwood PM, Gilbert DJ, Copeland NG, Jenkins NA and Nathans J: A family of secreted proteins contains homology to the cysteine-rich ligand-binding domain of frizzled receptors. Proc Natl Acad Sci USA 94: 2859-2863, 1997.
24. Jurado LAP, Coloma A and Cruces J: Identification of a human homolog of the Drosophila rotated abdomen gene (POMT1) encoding a putative protein O-mannosyltransferase, and assignment to human chromosome 9q34.1. Genomics 58: 171-180, 1999.