Serum leptin levels in overweight children and adolescents

British Journal of Nutrition

Volumn 101, Issue 8, 2009, Pages 1262-1266

  Antunes, Henedina ^a,b   Santos, Cristina ^c   Carvalho, Susana ^a  

^a Sao Marcos Hospital   (Portugal)

^b UNIVERSITY OF MINHO   (Portugal)

^c University of Porto   (Portugal)

Author keywords

Body mass index; Childhood overweight; Leptin; Sex

Indexed keywords

ASPARTATE AMINOTRANSFERASE; C PEPTIDE; INSULIN; LEPTIN;

ADOLESCENT; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; BLOOD CHEMISTRY; BODY MASS; CHILD; CHILD DEVELOPMENT; CLINICAL ASSESSMENT; CONTROLLED STUDY; DEVELOPMENTAL STAGE; FEMALE; HORMONE BLOOD LEVEL; HORMONE DETERMINATION; HUMAN; INSULIN BLOOD LEVEL; INSULIN RESISTANCE; MAJOR CLINICAL STUDY; MALE; OBESITY; PROTEIN BLOOD LEVEL; SEX DIFFERENCE; SYSTOLIC BLOOD PRESSURE;

ADOLESCENT; ANTHROPOMETRY; BLOOD PRESSURE; BODY MASS INDEX; CHILD; CHILD, PRESCHOOL; FEMALE; HUMANS; INFANT; LEPTIN; MALE; OBESITY; OVERWEIGHT; SEX FACTORS;

EID: 67649435591     PISSN: 00071145     EISSN: 14752662     Source Type: Journal    
DOI: 10.1017/S0007114508055682     Document Type: Article

References (21)

1. Ogden CL, Carroll MD, Curtin LR, McDowell MA, Tabak CJ & Flegal KM (2006) Prevalence of overweight and obesity in the United States, 1999-2004. JAMA 295, 1549-1555.
2. Padez C, Fernandes T, Mourão I, Moreira P & Rosado V (2004) Prevalence of overweight and obesity in 7-9 year-old Portuguese children: Trends in body mass index from 1970-2002. Am J Hum Biol 16, 670-678.
3. Baptista C (2002) Leptina (Leptin). Acta Pediatr Port 15, 281-285.
4. Moran O & Phillip M (2003) Leptin: Obesity, diabetes and other peripheral effects - a review. Pediatr Diabetes 4, 101-109.
5. Steinberger J, Steffen L, Jacobs DR Jr, Moran A, Hong CP & Sinaiko AR (2003) Relation of leptin to insulin resistance syndrome in children. Obes Res 11, 1124-1130.
6. Pilcová R, Sulcová J, Hill M, Bláha P & Lisá L (2003) Leptin levels in obese children: Effects of gender, weight reduction and androgens. Physiol Res 52, 53-60.
7. Johnson MS, Huang TT, Figueroa-Colon R, Dwyer JH & Goran MI (2001) Influence of leptin on changes in body fat during growth in African American and white children. Obes Res 9, 593-598.
8. Ramesh S & Sanyal AJ (2005) Evaluation and management of non-alcoholic steatohepatitis. J Hepatol 42, Suppl. 1, S2-S12.
9. Kliegman RM, Behrman RE, Jenson HB & Stanton BF (2007) Nelson Textbook of Pediatrics, 18th ed. Philadelphia, PA: Saunders.
10. Centers of Disease Control (2000) NHANES - United States Growth Charts - Data Files: Clinical Growth Charts. http://www.cdc.gov/nchs/about/major/ nhanes/growthcharts/clinical_charts.htm (accessed 29 June 2007).
11. McDowell MA, Fryar CD, Hirsch R & Ogden CL (2005) Anthropometric reference data for children and adults: U.S. population, 1999-2002. Adv Data 361, 1-5.
12. Schwimmer JB, Deutsch R, Rauch JB, Behling C, Newbury R & Lavine JE (2003) Obesity, insulin resistence, and other clinicopathological correlates of pediatric nonalcoholic fatty liver disease. J Pediatr 143, 500-505.
13. Fisher DA (2000) Alphabetical test listing (leptin). In The Quest Diagnostics Manual: Pediatric Endocrinology Tests and Methods, Specimen Requirements, Test Selection and Interpretation, p. 56 Madison, NJ: Quest Diagnostics.
14. Wabitsch M, Blum WF, Muche R, Braun M, Hube F, Rascher W, Heinze E, Teller W & Hauner H (1997) Contribution of androgens to the gender difference in leptin production in obese children and adolescents. J Clin Invest 100, 808-813.
15. Garcia-Mayor RV, Andrade MA, Rios M, Lage M, Dieguez C & Casanueva FF (1997) Serum leptin levels in normal children: Relationship to age, gender, body mass index, pituitary-gonadal hormones, and pubertal stage. J Clin Endocrinol Metab 82, 2849-2855.
16. Carlsson B, Ankarberg C, Rosberg S, Norjavaara E, Albertsson-Wikland K & Carlsson LM (1997) Serum leptin concentrations in relation to pubertal development. Arch Dis Child 77, 396-400.
17. Blum WF, Englaro P, Hanitsch S, et al. (1997) Plasma leptin levels in healthy children and adolescents: Dependence on body mass index, body fat mass, gender, pubertal stage and testosterone. J Clin Endocrinol Metab 82, 2904-2910.
18. Stylianou C, Galli-Tsinopoulou A, Farmakiotis D, Rousso I, Karamouzis M, Koliakos G & Nousia-Arvanitakis S (2007) Ghrelin and leptin levels in obese adolescents. Relationship with body fat and insulin resistance. Hormones (Athens) 6, 295-303.
19. Byrnes SE, Baur LA, Bermingham M, Brock K & Steinbeck K (1999) Leptin and total cholesterol are predictors of weight gain in pre-pubertal children. Int J Obes Relat Metab Disord 23, 146-150.
20. Fleisch AF, Agarwal N, Roberts MD, Han JC, Theim KR, Vexler A, Troendle J, Yanovski SZ & Yanovski JA (2007) Influence of serum leptin on weight and body fat growth in children at high risk for adult obesity. J Clin Endocrinol Metab 92, 948-954.
21. Savoye M, Dziura J, Castle J, DiPietro L, Tamborlane WV & Caprio S (2002) Importance of plasma leptin in predicting future weight gain in obese children: A two-and-a-half-year longitudinal study. Int J Obes Relat Metab Disord 26, 942-946.