Characteristics of Spontaneous Activity in the Bladder Trigone

European Urology

Volumn 56, Issue 2, 2009, Pages 346-354

  Roosen, Alexander ^a,c   Wu, Changhao ^a   Sui, Guiping ^a   Chowdhury, Rasheda A ^b   Patel, Pravina M ^b   Fry, Christopher H ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b NATIONAL HEART AND LUNG INSTITUTE   (United Kingdom)

^c LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

Author keywords

Cl channels; Connexin43; Guinea pig; L type Ca2+ channels; Spontaneous activity; Trigone

Indexed keywords

CALCIUM; CALCIUM CHANNEL; CALCIUM CHANNEL BLOCKING AGENT; CARBACHOL; FURA 2; LARGE CONDUCTANCE CALCIUM ACTIVATED POTASSIUM CHANNEL; NIFLUMIC ACID; PHENYLEPHRINE; THAPSIGARGIN; VERAPAMIL;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BLADDER MUSCLE; CELL ACTIVITY; CELL ISOLATION; CELL LEVEL; CONTROLLED STUDY; DETRUSOR MUSCLE; EPIFLUORESCENCE MICROSCOPE; GAP JUNCTION; IMMUNOFLUORESCENCE TEST; MUSCLE CONTRACTION; NONHUMAN; PRIORITY JOURNAL; SMOOTH MUSCLE; TRIGONE; UPREGULATION;

ANIMALS; ELECTROPHYSIOLOGICAL PROCESSES; GUINEA PIGS; MALE; MUSCLE CONTRACTION; MUSCLE, SMOOTH; URINARY BLADDER;

EID: 67649424729     PISSN: 03022838     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.eururo.2008.06.048     Document Type: Article

References (29)

1. ®) intradetrusor injections in adults with neurogenic detrusor overactivity/neurogenic overactive bladder: a systematic literature review. Eur Urol 53 (2008) 275-287
2. Patel A.K., Patterson J.M., and Chapple C.R. Botulinum toxin injections for neurogenic and idiopathic detrusor overactivity. A critical analysis of results. Eur Urol 50 (2006) 684-710
3. Tanagho E.A. The ureterovesical junction. In: Chisholm G.D., and Williams D.I. (Eds). Scientific Foundations of Urology (1982), Heinemann, London 395-404
4. Oswald J., Schwentner C., Lunacek A., et al. Reevaluation of the fetal muscle development of the vesical trigone. J Urol 176 (2006) 1166-1170
5. Andersson K.E., and Alm P. Neurogenic nitric oxide and the lower urinary tract. In: Toda N., Moncada S., Furchgott R.F., and Higgs E.A. (Eds). Nitric Oxide and Peripheral Nervous System (2000), Pergamon, London 77-97
6. Persson K., Alm P., Johansson K., Larsson B., and Andersson K.E. Nitric oxide synthase in pig lower urinary tract: immunohistochemistry, NADPH diaphorase histochemistry and functional effects. Br J Pharmacol 110 (1993) 521-530
7. Brading A.F. Spontaneous activity of lower urinary tract smooth muscles: correlation between ion channels and tissue function. J Physiol 570 (2006) 13-22
8. Sibley G.N. A comparison of spontaneous and nerve-mediated activity in bladder muscle from man, pig and rabbit. J Physiol 354 (1984) 431-433
9. Callahan S.M., and Creed K.E. Electrical and mechanical activity of the isolated lower urinary tract of the guinea-pig. Br J Pharmacol 74 (1981) 353-358
10. 2+ stores in guinea-pig detrusor smooth muscle. J Physiol 538 (2002) 357-369
11. Montgomery B.S., Thomas P.J., and Fry C.H. The actions of extracellular magnesium on isolated human detrusor muscle function. Br J Urol 70 (1992) 262-268
12. Sergeant G.P., Hollywood M.A., McCloskey K.D., Thornbury K.D., and McHale N.G. Specialised pacemaking cells in the rabbit urethra. J Physiol 526 (2000) 359-366
13. 2+ signalling in urethral interstitial cells of Cajal. J Physiol 576 (2006) 715-720
14. Fry C.H., and Langley S.M. Ion-selective Electrodes in Biomedical Systems (2001), Harwood Press, London
15. Hashitani H., Brading A.F., and Suzuki H. Correlation between spontaneous electrical, calcium and mechanical activity in detrusor smooth muscle of the guinea-pig bladder. Br J Pharmacol 141 (2004) 183-193
16. Roosen A., Wu C., Sui G.P., and Fry C.H. Synergistic effects in neuromuscular activation and calcium-sensitization in the bladder trigone. BJU Int 101 (2008) 610-614
17. 2+ channels in human detrusor smooth muscle. BJU Int 92 (2003) 476-482
18. Hashitani H., Fukuta H., Takano H., Klemm M.F., and Suzuki H. Origin and propagation of spontaneous excitation in smooth muscle of the guinea-pig urinary bladder. J Physiol 530 (2001) 273-286
19. 2+ stores in atypical smooth muscle cell autorhythmicity in the mouse renal pelvis. Br J Pharmacol 152 (2007) 1248-1259
20. - current by depolarizing steps in rabbit urethral interstitial cells. Am J Physiol Cell Physiol 285 (2003) C327-C333
21. Wu C., Sui G.P., and Fry C.H. Purinergic regulation of guinea pig suburothelial myofibroblasts. J Physiol 559 (2004) 231-243
22. Ikeda Y., Fry C., Hayashi F., Stolz D., Griffiths D., and Kanai A. Role of gap junctions in spontaneous activity of the rat bladder. Am J Physiol Renal Physiol 293 (2007) F1018-F1025
23. Sui G.P., Coppen S.R., Dupont E., et al. Impedance measurements and connexin expression in human detrusor muscle from stable and unstable bladders. BJU Int 92 (2003) 297-305
24. John H., Hauri D., Bangerter U., and Elbadawi A. Ultrastructure of the trigone and its functional implications. Urol Int 67 (2001) 264-271
25. Thomson A.S., Dabhoiwala N.F., Verbeek F.J., and Lamers W.H. The functional anatomy of the ureterovesical junction. Br J Urol 73 (1994) 284-291
26. 2+ signals in detrusor smooth muscles of the guinea-pig urinary bladder. J Physiol 559 (2004) 567-581
27. Davidson R.A., and McCloskey K.D. Morphology and localization of interstitial cells in the guinea pig bladder: structural relationships with smooth muscle and neurons. J Urol 173 (2005) 1385-1390
28. Troxel S.A., Jones A.W., Magliola L., and Benson J.S. Physiologic effect of nifedipine and tamsulosin on contractility of distal ureter. J Endourol 20 (2006) 565-568
29. Sergeant G.P., Thornbury K.D., McHale N.G., and Hollywood M.A. Interstitial cells of Cajal in the urethra. J Cell Mol Med 10 (2006) 280-291