5-HT1A receptor activation is necessary for 5-MeODMT-dependent potentiation of feeding inhibition

Pharmacology Biochemistry and Behavior

Volumn 93, Issue 3, 2009, Pages 349-353

  Duvvuri, Vikas ^a   Risbrough, Victoria B ^a   Kaye, Walter H ^a   Geyer, Mark A ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Anorexia; Anxiety; Feeding; Impulsivity; Novelty; Serotonin

Indexed keywords

SEROTONIN 1A RECEPTOR; SEROTONIN AGONIST; 5 METHOXY N,N DIMETHYLTRYPTAMINE; DIAZEPAM; HYPNOTIC SEDATIVE AGENT; N [2 [4 (2 METHOXYPHENYL) 1 PIPERAZINYL]ETHYL] N (2 PYRIDYL)CYCLOHEXANECARBOXAMIDE; PIPERAZINE DERIVATIVE; PYRIDINE DERIVATIVE; SEROTONIN ANTAGONIST;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANOREXIA NERVOSA; ANXIETY DISORDER; ARTICLE; AVOIDANCE BEHAVIOR; CONTROLLED STUDY; IMPULSIVENESS; MALE; MOUSE; NONHUMAN; PREDICTION; PRIORITY JOURNAL; PROTEIN FUNCTION; RECEPTOR BINDING; SEROTONINERGIC SYSTEM; ANIMAL; C57BL MOUSE; DRUG ANTAGONISM; DRUG EFFECT; DRUG POTENTIATION; ENVIRONMENT; EXPLORATORY BEHAVIOR; FEAR; FEEDING BEHAVIOR; STATISTICAL ANALYSIS;

MUS;

ANIMALS; DATA INTERPRETATION, STATISTICAL; DIAZEPAM; ENVIRONMENT; EXPLORATORY BEHAVIOR; FEAR; FEEDING BEHAVIOR; HYPNOTICS AND SEDATIVES; MALE; METHOXYDIMETHYLTRYPTAMINES; MICE; MICE, INBRED C57BL; PIPERAZINES; PYRIDINES; RECEPTOR, SEROTONIN, 5-HT1A; SEROTONIN AGONISTS; SEROTONIN ANTAGONISTS;

EID: 67649421627     PISSN: 00913057     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.pbb.2009.05.014     Document Type: Article

References (37)

1. 1A receptors of the in vivo release of 5-HT and DA in mouse frontal cortex. Neuropharmacology 45 (2003) 1050-1056
2. 2A receptors in pyramidal neurons of prefrontal cortex. Cereb Cortex 14 (2004) 281-299
3. American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders-Fourth Edition-Text Revision (DSM-IV-TR) (2000), American Psychiatric Association, Washington, DC
4. 1A receptor binding after recovery from anorexia nervosa. Int J Neuropsychopharmacol 7 Suppl 1 (2004) S474
5. 11C]WAY100635. Arch Gen Psychiatry 62 (2005) 1032
6. 2A receptor activity in individuals ill with anorexia nervosa. Biol Psychiatry 61 (2007) 1090-1099
7. Belzung C., and Griebel G. Measuring normal and pathological anxiety-like behaviour in mice: a review. Behav Brain Res 125 (2001) 141-149
8. Blanchard D., Griebel G., and Blanchard R. Mouse defensive behaviors: pharmacological and behavioral assays for anxiety and panic. Neurosci Biobehav Rev 25 (2001) 205-218
9. Carli M., Baviera M., Invernizzi R., and Balducci C. Dissociable contribution of 5-HT1A and 5-HT2A receptors in the medial prefrontal cortex to different aspects of executive control such as impulsivity and compulsive perseveration in rats. Neuropsychopharmacology 31 (2006) 757-767
10. Cohen H. Anxiolytic effect and memory improvement in rats by antisense oligodeoxynucleotide to 5-hydroxytryptamine-2A precursor protein. Depress Anxiety 22 (2005) 84-93
11. Davidson J. First-line pharmacotherapy approaches for generalized anxiety disorder. J Clin Psychiatry 70 (2009) 25-31
12. Dulawa C., and Hen R. Recent advances in animal models of chronic antidepressant effects: the noventy-induced hypophagia test. Neurosci Biobehav Rev 29 (2005) 771-783
13. File S.E., Kenny P.J., and Cheeta S. The role of the dorsal hippocampal serotonergic and cholinergic systems in the modulation of anxiety. Pharmacol Biochem Behav 66 (2000) 65
14. Frank G., and Kaye W.H. Positron emission tomography studies in eating disorders: multireceptor brain imaging, correlates with behavior and implications for pharmacotherapy. Nucl Med Biol 32 (2005) 755-761
15. Frank G.K., Kaye W.H., Weltzin T.E., Perel J., Moss H., McConaha C., et al. Altered response to meta-chlorophenylpiperazine in anorexia nervosa: support for a persistent alteration of serotonin activity after short-term weight restoration. Int J Eat Disord 30 (2001) 57-68
16. Frank G., Meltzer C.C., Price J., Drevets W.C., Greer P., Mathis C., et al. Alterations of 5-HT1A and 2A receptors persist after recovery from anorexia and bulimia nervosa. Society of Biological Psychiatry (2002), Biological Psychiatry, Philadelphia, PA 11S
17. Geyer M., and Markou A. The role of preclinical models in the development of psychotropic drugs. In: Davis K.L., Charney D., Coyle J.T., and Nemeroff C. (Eds). Neuropsychopharmacology: The Fifth Generation of Progress (2002), Williams & Wilkins, Philadelphia: Lippincott 445-455
18. Griebel G., Perrault G., and Sanger D. A comparative study of the effects of selective and non-selective 5-HT2 receptor subtype antagonists in rat and mouse models of anxiety. Neuropsychopharmacology 36 (1997) 793-802
19. 1A receptor acts during development to establish normal anxiety-like behaviour in the adult. Nature 416 (2002) 396-400
20. Hettema J., Neale M., and Kendler K. A review and metaanalysis of the genetic epidemiology of anxiety disorders. Am J Psychiatry 158 (2001) 1568-1578
21. Jennings K., Loder M., Sheward W., Pei Q., Deacon R., Benson M., et al. Increased expression of the 5-HT transporter confers a low-anxiety phenotype linked to decreased 5-HT transmission. J Neurosci 26 (2006) 8955-8964
22. Kaye W.H., Barbarich N.C., Putnam K., Gendall K.A., Fernstrom J., Fernstrom M., et al. Anxiolytic effects of acute tryptophan depletion in anorexia nervosa. Int J Eat Disord 33 (2003) 257-267
23. Kaye W., Bulik C., Thornton L., Barbarich N., Masters K., Fichter M., et al. Comorbidity of anxiety disorders with anorexia and bulimia nervosa. Am J Psychiatry 161 (2004) 2215-2221
24. 2A receptors in rats. Psychopharmacology (Berl) 140 (1998) 69-74
25. Lang P., Davis M., and Ohman A. Fear and anxiety: animal models and human cognitive psychophysiology. J Affect Disord 61 (2000) 137-159
26. Merali Z., Levac C., and Anisman H. Validation of a simple, ethologically relevant paradigm for assessing anxiety in mice. Biol Psychiatry 54 (2003) 552-565
27. 2A receptor binding and personality traits in healthy subjects: A positron emission tomography study. Neurolmage 17 (2002) 1470-1478
28. Ramboz S., Oosting R., Amara D.A., Kung H.F., Blier P., Mendelsohn M., et al. Serotonin receptor 1A knockout: an animal model of anxiety-related disorder. Proc Natl Acad Sci U S A 95 (1998) 14476-14481
29. Rochford J., Beaulieu S., Rousse I., Glowa J., and Barden N. Behavioral reactivity to aversive stimuli in a transgenic mouse model of impaired glucocorticoid (type II) receptor function: effects of diazepam and FG-7142. Psychopharmacology (Berl) 132 (1997) 145-152
30. 2A receptor in pyramidal and GABAergic neurons of the rat prefrontal cortex. Cereb Cortex (2004) 1
31. Shephard R., and Broadhurst P.L. Hyponeophagia and arousal in rats: effects of diazepam, 5-methoxy=N, N-dimethyltryptamine, d-amphetamine and food deprivation. Psychopharmacology (Berl) 78 (1982) 368-372
32. Shephard R., and Broadhurst P.B.P.L. Hyponeophagia in the Roman rat strains: effects of 5-methoxy-N, N-dimethyltryptamine, diazepam, methysergide and the steroisomers of propranolol. Eur J Pharmacol 95 (1983) 177-184
33. 11C]WAY-100635 PET investigation in healthy volunteers. Am J Psychiatr 158 (2001) 1326-1328
34. Trullas R., and Skolnick P. Differences in fear motivated behaviors among inbred mouse strains. Psychopharmacology (Berl) 111 (1993) 323-331
35. Varnas K., Halldin C., and Hall H. Autoradiographic distribution of serotonin transporters and receptor subtypes in human brain. Hum Brain Mapp 22 (2004) 246-260
36. Weisstaub N., Zhou M., Lira A., Lambe E., Gonzalez-Maeso J., Hornung J., et al. Cortical 5-HT2A receptor signaling modulates anxiety-like behaviors in mice. Science 313 (2006) 536-540
37. Winstanley C.A., Chudasama Y., Dalley J., Theobald D., Glennon J., and Robbins T.W. Intra-prefrontal 8-OH-DPAT and M100907 improve visuospatial attention and decrease impulsivity on the five-choice serial reaction time task in rats. Psychopharmacology (Berl) 167 (2003) 304-314