Polymorphisms in the renin-angiotensin system and outcome of very-low-birthweight infants

Neonatology

Volumn 97, Issue 1, 2009, Pages 10-14

  Spiegler, J ^a   Gilhaus, A ^a   Konig I R ^a   Kattner, E ^b   Vochem, M ^c   Kuster H ^d   Moller J ^e   Muller D ^f   Kribs, A ^g   Segerer, H ^h   Wieg, C ⁱ   Nikischin, W ^j   Von Der Wense, A ^k   Gebauer, C ^l   Herting, E ^a   Gopel W ^a  

^a UNIVERSITY OF LÜBECK   (Germany)

^b Kinderklinik auf der Bult   (Germany)

^c OLGAHOSPITAL   (Germany)

^d UNIVERSITY OF GREIFSWALD   (Germany)

^e Childrens Hospital Saarbrucken   (Germany)

^f Children's Hospital   (Germany)

^g UNIVERSITY OF COLOGNE   (Germany)

^h Kinderklinik St Hedwig   (Germany)

ⁱ Aschaffenburg Hospital   (Germany)

^j UNIVERSITY OF KIEL   (Germany)

^k Altonaer Kinderkrankenhaus   (Germany)

^l UNIVERSITY HOSPITAL LEIPZIG   (Germany)

more..

Author keywords

Bronchopulmonary dysplasia; Deletion insertion polymorphism of the angiotensin converting enzyme; Intraventricular hemorrhage; Persistent ductus arteriosus; Very low birthweight infants

Indexed keywords

ANGIOTENSIN 1 RECEPTOR; DIPEPTIDYL CARBOXYPEPTIDASE; INSULIN; OXYGEN; SURFACTANT;

ARTICLE; ARTIFICIAL VENTILATION; BRAIN HEMORRHAGE; CONTROLLED STUDY; DEATH; DNA POLYMORPHISM; ENZYME POLYMORPHISM; FEMALE; GENOTYPE; HUMAN; INDEL MUTATION; INFANT; INTESTINE PERFORATION; LUNG DYSPLASIA; MAJOR CLINICAL STUDY; MALE; NECROTIZING ENTEROCOLITIS; OUTCOME ASSESSMENT; PATENT DUCTUS ARTERIOSUS; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; RENIN ANGIOTENSIN ALDOSTERONE SYSTEM; RETROLENTAL FIBROPLASIA; SEPSIS; VERY LOW BIRTH WEIGHT;

ADULT; COHORT STUDIES; FEMALE; GENETIC PREDISPOSITION TO DISEASE; GENETIC TESTING; HUMANS; INFANT; INFANT, NEWBORN; INFANT, PREMATURE, DISEASES; INFANT, VERY LOW BIRTH WEIGHT; MALE; POLYMORPHISM, SINGLE NUCLEOTIDE; PREGNANCY; PREGNANCY OUTCOME; PROSPECTIVE STUDIES; RENIN-ANGIOTENSIN SYSTEM;

EID: 67649418108     PISSN: 16617800     EISSN: 16617819     Source Type: Journal    
DOI: 10.1159/000226602     Document Type: Article

References (17)

1. Imai Y, Kuba K, Rao S, Huan Y, Guo F, Guan B, Yang P, Sarao R, Wada T, Leong-Poi H, Crackower MA, Fukamizu A, Hui CC, Hein L, Uhlig S, Slutsky AS, Jiang C, Penninger JM: Angiotensin-converting enzyme 2 protects from severe acute lung failure. Nature 2005; 436: 112-116.
2. Adamzik M, Frey U, Sixt S, Knemeyer L, Beiderlinden M, Peters J, Siffert W: ACE I/D but not AGT (-6)A/G polymorphism is a risk factor for mortality in ARDS. Eur Respir J 2007; 29: 482-488.
3. Baudin B: Polymorphism in angiotensin II receptor genes and hypertension. Exp Physiol 2004; 90: 277-282.
4. Harding D, Dhamrait S, Marlow N, Whitelaw A, Gupta S, Humphries S, Montgomery H: Angiotensin-converting enzyme DD genotype is associated with worse perinatal cardiorespiratory adaptation in preterm infants. J Pediatr 2003; 143: 746-749.
5. Kazzi SN, Quasney MW: Deletion allele of angiotensin-converting enzyme is associated with increased risk and severity of bronchopulmonary dysplasia. J Pediatr 2005; 147: 818-822.
6. Sivasli E, Yurdakök M, Babaoglu E, Karabulut H, Yigit S, Babaoglu M, Tekinalp G, Tükün A: ACE gene deletion/deletion polymorphism may be a protective factor for respiratory distress in preterm infants. Turk J Pediatr 2007; 49: 69-74.
7. Yanamandra K, Loggins J, Baier RJ: The angiotensin converting enzyme insertion/deletion polymorphism is not associated with an increased risk of death or bronchopulmonary dysplasia in ventilated very low birth weight infants. BMC Pediatr 2004; 4: 26.
8. Haider MZ, Devarajan LV, Al-Essa M, Kumar H: Angiotensin-converting enzyme gene insertion/deletion polymorphism in Kuwaiti children with retinopathy of prematurity. Biol Neonate 2002; 82: 84-88. (Pubitemid 34899249)
9. Han T, Wang X, Cui Y, Ye H, Tong X, Piao M: Relationship between angiotensin-converting enzyme gene insertion or deletion polymorphism and insulin sensitivity in healthy newborns. Pediatrics 2007; 119: 1089-1094.
10. Treszl A, Szabo M, Dunai G, Nobilis A, Kocsis I, Machay T, Tulassay T, Vasarhelyi B: Angiotensin II type 1 receptor A1166C polymorphism and prophylactic indomethacin treatment induced ductus arteriosus closure in very low birth weight neonates. Pediatr Res 2003; 54: 753-755.
11. Härtel C, König I, Köster S, Kattner E, Kuhls E, Küster H, Möller J, Müller D, Kribs A, Segerer H, Wieg C, Herting E, Göpel W: Genetic polymorphisms of hemostasis genes and primary outcome of very low birth weight infants. Pediatrics 2006; 118: 683-689.
12. Wellek S: Tests for establishing compatibility of an observed genotype distribution with Hardy-Weinberg equilibrium in the case of a biallelic locus. Biometrics 2004; 60: 694-703.
13. Gainer JV, Hunley TE, Kon V, Nadeau JH, Muldowney JA 3rd, Brown NJ: Angiotensin II type I receptor polymorphism in African Americans lower frequency of the C1166 variant. Biochem Mol Biol Int 1997; 43: 227-231.
14. Bender JW, Davitt MK, Jose P: Angiotensin- I-converting enzyme activity in term and premature infants. Biol Neonate 1978; 34: 19-23.
15. Walther T, Faber R, Maul B, Schultheiss HP, Siems WE, Stepan H: Fetal, neonatal cord, and maternal plasma concentrations of angiotensin- converting enzyme (ACE). Prenat Diagn 2002; 22: 111-113.
16. Baier JR, Loggins J, Yanamandra K: Angiotensin converting enzyme insertion/deletion polymorphism does not alter sepsis outcome in ventilated very low birth weight infants. J Perinatol 2005; 25: 205-209.
17. Harding D, Baines PB, Brull D, Vassiliou V, Ellis I, Hart A, Thomson AP, Humphries SE, Montgomery HE: Severity of meningococcal disease in children and the angiotensin-converting enzyme insertion/deletion polymorphism. Biol Neonate 2002; 82: 84-88.