ACE gene deletion/deletion polymorphism may be a protective factor for respiratory distress in preterm infants

Turkish Journal of Pediatrics

Volumn 49, Issue 1, 2007, Pages 69-74

  Sivasli, Ercan ^a   Yurdakök, Murat ^a   Babaoǧlu, Elif ^b   Karabulut, Halil ^b   Yiǧit, Şule ^a   Babaoǧlu, Melih ^a   Tekinalp, Gülsevin ^a   Tükün, Ajlan ^b  

^a HACETTEPE UNIVERSITY   (Turkey)

^b ANKARA UNIVERSITY   (Turkey)

Author keywords

ACE gene polymorphisms; Preterm infant; Respiratory distress

Indexed keywords

DIPEPTIDYL CARBOXYPEPTIDASE;

ARTICLE; ARTIFICIAL VENTILATION; BIRTH WEIGHT; BLOOD SAMPLING; CARDIOVASCULAR DISEASE; CONTROLLED STUDY; FEMALE; FOLLOW UP; GENE DELETION; GENE INSERTION; GENETIC POLYMORPHISM; GENOTYPE; GESTATIONAL AGE; HOSPITALIZATION; HUMAN; INFANT; LUNG DISEASE; MAJOR CLINICAL STUDY; MALE; OXYGEN CONSUMPTION; POLYMERASE CHAIN REACTION; PREMATURITY; RESPIRATORY DISTRESS; RISK FACTOR;

FEMALE; GENE DELETION; GENOTYPE; HUMANS; INFANT, NEWBORN; INFANT, PREMATURE; INTENSIVE CARE UNITS, NEONATAL; MALE; PEPTIDYL-DIPEPTIDASE A; POLYMORPHISM, GENETIC; RESPIRATORY DISTRESS SYNDROME, NEWBORN; RISK;

EID: 34247100315     PISSN: 00414301     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (34)

1. Griendling KK, Murphy TJ, Alexander RW. Molecular biology of the renin-angiotensin system. Circulation 1993; 87: 1816-1828.
2. Harding DR, Dhamrait S, Devadason D, et al. Does angiotensin-1 converting enzyme genotype influence motor or cognitive development after pre-term birth? J Neuroinflammation 2005, 2: 1-6.
3. Akisu M, Balim Z, Cetin H, et al. The role of angiotensin-converting enzyme and apolipoprotein-E gene polymorphisms on lipid compositions in newborn infants with intrauterine growth restriction. Early Hum Dev 2004; 78: 95-103.
4. Schutz S, Le Moullec JM, Corvol P, Gasc JM. Early expression of all components of the renin-angiotensin system in human development. Am J Pathol 1996; 149: 2067-2079.
5. Nielsen AH, Schauser KH, Poulsen K. Current topic: the uteroplacental renin- angiotensin system. Placenta 2000; 21: 468-477.
6. Pitt BR, Lister G, Davies P, Reid L. Correlation of pulmonary ACE activity and capillary surface area during postnatal development. J Appl Physiol 1987; 62: 2031-2041.
7. Touyz RM, Schiffrin EL. Signal transduction mechanisms mediating the physiological and pathophysiological actions of angiotensin II in vascular smooth muscle cells. Pharmacol Rev 2000; 52: 639-672.
8. Esther CR, Marino EM, Howard TE, et al. The critical role of tissue angiotensin-converting enzyme as revealed by gene targeting in mice. J Clin Invest 1997; 99: 2375-2385.
9. Rigat B, Hubert C, Alhenc-Gelas F, Cambien F, Corvol P, Soubrier F. An insertion/deletion polymorphism in the angiotensin I-converting enzyme gene accounting for half the variance of serum enzyme levels. J Clin Invest 1990; 86: 1343-1346.
10. Rigat B, Hubert C, Corvol P, Soubrier F. PCR detection of the insertion/ deletion polymorphism of the human angiotensin converting enzyme gene (DCP1) (dipeptidyl carboxypeptidase 1). Nuc Acid Res 1992; 20: 1433.
11. Kanazawa H, Okamoto T, Hirata K. Yoshikawa J. Deletion polymorphisms in the angiotensin converting enzyme gene are associated with pulmonary hypertension evoked by exercise challenge in patients with chronic obstructive pulmonary disease. Am J Respir Crit Care Med 2000; 162: 1235-1238.
12. Aldashev AA, Sarybaev AS, Sydykov AS, et al. Characterization of high-altitude pulmonary hypertension in the Kyrgyz: association with angiotensin-converting enzyme genotype. Am J Respir Crit Care Med 2002; 166: 1396-1402.
13. Marshall R, Webb S, Bellingan G, et al. Angiotensin converting enzyme insertion/deletion polymorphism is associated with susceptibility and outcome in acute respiratory distress syndrome. Am J Respir Crit Care Med 2002; 166: 646-650.
14. Kirkpatrick.BV, Mueller DG. Respiratory disorders in the newborn. In: Chernick V, Boat TF, Edwin L (eds). Kendig's Disorders of the Respiratory Tract in Children (6th ed). Philadelphia: WB Saunders; 1998: 328-364.
15. Rodrigues RJ, Martin RJ, Fanaroff AA. The respiratory distress syndrome and its management. In: Fanaroff AA, Martin RJ (eds). Neonatal Perinatal Medicine: Diseases of the Fetus and infant (7th ed) Vol. 2. St. Louis: Mosby; 2002: 1001-1011.
16. Miller MJ, Fanaroff AA, Martin RJ. Respiratory disorders in preterm and term infants. In: Fanaroff AA, Martin RJ (eds). Neonatal-Perinatal Medicine Disease of the Fetus and Infant (7th ed) Vol. 2. St Louis: Mosby; 2002: 1025-1049.
17. Nair PM, Bataclan MF. Persistent pulmonary hypertension of the newborn. Saudi Med J 2004; 25: 693-699.
18. Whitsett JA, Rice WR, Warner BB, Wert SE, Gloria SP. Acute respiratory disorders. In: MacDonald MG, Mullett MD, Seshia MK (eds). Pathophysiology and Management of the Newborn (6th ed). Philadelphia: Lippincott Williams & Wilkins; 2005: 553-577.
19. Wojciak-Stothard B, Haworth SG. Perinatal changes in pulmonary vascular endothelial function. Pharmacol Ther 2006; 109: 78-91.
20. Newton CR, Curran B, Victorino GP. Angiotensin II type 1 receptor activation increases microvascular permeability via a calcium dependent process. J Surg Res 2005; 123: 33-39.
21. Marshall R, Gohlke P, Chambers RC, et al. Angiotensin II and the fibroproliferative response to acute lung injury. Am J Physiol Lung Cell Mol Physiol 2004; 286: 156-614.
22. Wang R, Zagariya A, Ibarra-Sunga O, et al. Angiotensin II induces apoptosis in human and rat alveolar epithelial cells. Am J Physiol 1999; 276: 885-889.
23. Idell S, Kueppers F, Lippmann M, Rosen H, Niederman M, Fein A. Angiotensin converting enzyme in bronchoalveolar lavage in ARDS. Chest 1987; 91: 52-56.
24. Harding D, Dhamrait S, Marlow N, et al. Angiotensin-converting enzyme DD genotype is associated with worse perinatal cardiorespiratory adaptation in preterm infants. J Pediatr 2003; 143: 746-749.
25. Yamanadra K, Loggins J, Baier RJ. The angiotensin converting enzyme insertion/deletion polymorphism is not associated with an increased risk of death or bronchopulmonary dysplasia in ventilated very low birth weight infants. BMC Pediatrics 2004; 4: 26-32.
26. Kazzi N, Qasney WQ. Deletion allele of angiotensin-converting enzyme is associated with increased risk and severity of bronchopulmonary dysplasia. J Pediatr 2005; 147: 818-822.
27. Barr M. Teratogen update: angiotensin-converting enzyme inhibitors. Teratology 1994; 50: 399-409.
28. Seaver LH. Adverse environmental exposures in pregnancy: teratology in adolescent medicine practice. Adolesc Med 2002; 13: 269-291.
29. Lumbers ER, Bernasconi C, Burrell JH. Effects of inhibition of the maternal reninangiotensin system on maternal and fetal responses to drainage of fetal fluids. Can J Physiol Pharmacol 1996; 74: 973-982.
30. Walther T, Faber R, Maul B, Schultheiss HP, Siems WE, Stepan H. Fetal, neonatal cord, and maternal plasma concentrations of angiotensin-converting enzyme (ACE). Prenat Diagn 2002; 22: 111-113.
31. Crisan D, Carr J. Angiotensin I-converting enzyme: genotype and disease associations. J Mol Diagn 2000; 2: 105-115.
32. Marshall R. The pulmonary renin-angiotensin system. Curr Pharm Des 2003; 9: 715-722.
33. Costerousse O, Allegrini J, Lopez M, Alhenc-Gelas F. Angiotensin I-converting enzyme in human circulating mononuclear cells: genetic polymorphism of expression in T-lymphocytes. Biochem J 1993; 290: 33-40.
34. Harrap SB, Davidson HR, Connor JM, et al. The angiotensin I converting enzyme gene and predisposition to high blood pressure. Hypertension 1993; 21: 455-460.