Targeting CpG DNA to screen and isolate anti-sepsis fraction and monomers from traditional Chinese herbs using affinity biosensor technology

International Immunopharmacology

Volumn 9, Issue 9, 2009, Pages 1021-1031

  Liu, Xin ^a   Cheng, Juan ^a   Zheng, Xinchuang ^a   Chen, Yiguo ^a   Wu, Chong ^a   Li, Bin ^a   Fu, Jianfeng ^a   Cao, Hongwei ^a   Lu, Yongling ^a   Li, Jun ^a   Zheng, Jiang ^a   Zhou, Hong ^a  

^a THIRD MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

Affinity biosensor; CpG DNA; Radix et Rhizoma Rhei; Rhein; Sepsis; Traditional Chinese herbs

Indexed keywords

BACTERIAL DNA; EMODIN; FRACTION D; LIPID A; LIPOPOLYSACCHARIDE; MESSENGER RNA; MONOMER; PLANT EXTRACT; RHEIN; SILICA GEL; TOLL LIKE RECEPTOR 9; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BINDING AFFINITY; BIOSENSOR; CHEMICAL STRUCTURE; CHINESE HERB; CONTROLLED STUDY; CPG ISLAND; CYTOKINE RELEASE; DNA BINDING; DRUG ACTIVITY; ESCHERICHIA COLI; EVALUATION; FEMALE; GEL CHROMATOGRAPHY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RADIX ET RHIZOMA RHEI; SEPSIS; UPREGULATION;

ACONITUM; ANIMALS; ANTHRAQUINONES; BIOSENSING TECHNIQUES; CELL LINE; CHEMICAL FRACTIONATION; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CPG ISLANDS; DNA, BACTERIAL; DRUG EVALUATION, PRECLINICAL; DRUG SYNERGISM; DRUGS, CHINESE HERBAL; EMODIN; ENZYME INHIBITORS; ESCHERICHIA COLI; ESCHERICHIA COLI INFECTIONS; FEMALE; GENE EXPRESSION REGULATION; IMMUNITY, INNATE; LIPID A; MACROPHAGES; MICE; MICE, INBRED STRAINS; PHYTOTHERAPY; PROTEIN BINDING; SEPSIS; TOLL-LIKE RECEPTOR 9; TUMOR NECROSIS FACTOR-ALPHA;

EID: 67649413073     PISSN: 15675769     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.intimp.2009.03.023     Document Type: Article

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