Development of an analytical method for the unambiguous structure elucidation of cyclic peptides with special appliance for hepatotoxic desmethylated microcystins

Toxicon

Volumn 54, Issue 3, 2009, Pages 302-312

  Krüger, Thomas ^a   Christian, Bernd ^a   Luckas, Bernd ^a  

^a FRIEDRICH SCHILLER UNIVERSITY JENA   (Germany)

Author keywords

Amino acids; Dehydroalanine; Dehydrobutyrine; Desmethyl microcystins; dm MC RR; Hepatotoxins; Microcystis aeruginosa; N methyldehydroalanine; Tandem mass spectrometry

Indexed keywords

CYANOGINOSIN YR; CYCLOPEPTIDE; MICROCYSTIN; MICROCYSTIN LR; MICROCYSTIN RR; OXOACID; UNCLASSIFIED DRUG;

ALGAL BLOOM; AMINO ACID ANALYSIS; AMINO ACID COMPOSITION; ARTICLE; CONTROLLED STUDY; DEMETHYLATION; DERIVATIZATION; GERMANY; HARMFUL ALGA; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LIQUID CHROMATOGRAPHY; MICROCYSTIS AERUGINOSA; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL; PROTEIN HYDROLYSIS; RISK ASSESSMENT; SEPARATION TECHNIQUE; STEREOSPECIFICITY; TANDEM MASS SPECTROMETRY; TOXIN ANALYSIS;

CHROMATOGRAPHY, HIGH PRESSURE LIQUID; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; LIVER; MICROCYSTINS; PEPTIDES, CYCLIC; PROTEIN CONFORMATION; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; SPECTROPHOTOMETRY, ULTRAVIOLET; TANDEM MASS SPECTROMETRY;

ALGAE; CYANOBACTERIA; MICROCYSTIS AERUGINOSA;

EID: 67649401697     PISSN: 00410101     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.toxicon.2009.04.020     Document Type: Article

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