Association of chromosomal locus 8q24 and risk of prostate cancer: A hospital-based study of German patients treated with brachytherapy

Urologic Oncology: Seminars and Original Investigations

Volumn 27, Issue 4, 2009, Pages 373-376

  Meyer, Andreas ^a   Schürmann, Peter ^a   Ghahremani, Maryam ^a   Kocak, Ertan ^a   Brinkhaus, Maria Jantje ^a   Bremer, Michael ^a   Karstens, Johann H ^a   Hagemann, Jörn ^a   Machtens, Stefan ^a   Dörk, Thilo ^a  

^a HANNOVER MEDICAL SCHOOL   (Germany)

Author keywords

Association study; Brachytherapy; Genetic predisposition; Prostate cancer susceptibility

Indexed keywords

EXODEOXYRIBONUCLEASE V; GENOMIC DNA;

ADULT; AGED; ALLELE; ARTICLE; BRACHYTHERAPY; BREAST CANCER; CANCER PATIENT; CANCER RISK; CANCER SUSCEPTIBILITY; CHROMOSOME 8Q; CONTROLLED STUDY; DISEASE ASSOCIATION; GENE FREQUENCY; GENE LOCUS; GENETIC ASSOCIATION; GENETIC MARKER; GENOMICS; GENOTYPE; GERMANY; HETEROZYGOTE; HOMOZYGOTE; HUMAN; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; PROSTATE CANCER; RISK ASSESSMENT; SINGLE NUCLEOTIDE POLYMORPHISM;

ADENOCARCINOMA; ADULT; AGED; BRACHYTHERAPY; CHROMOSOMES, HUMAN, PAIR 8; GENETIC PREDISPOSITION TO DISEASE; GENOME-WIDE ASSOCIATION STUDY; GERMANY; HUMANS; MALE; MIDDLE AGED; POLYMORPHISM, GENETIC; POLYMORPHISM, SINGLE NUCLEOTIDE; PROSTATIC NEOPLASMS; RISK;

EID: 67649382931     PISSN: 10781439     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.urolonc.2008.04.010     Document Type: Article

References (20)

1. Lichtenstein P., Holm N.V., Verkasalo P.K., et al. Environmental and heritable factors in the causation of cancer-analyses of cohorts of twins from Sweden, Denmark, and Finland. N Engl J Med 343 (2000) 78-85
2. Gonzalgo M.L., and Isaacs W.B. Molecular pathways to prostate cancer. J Urol 170 (2003) 2444-2452
3. Johns L.E., and Houlston R.S. A systematic review and meta-analysis of familial prostate cancer risk. BJU Int 91 (2003) 789-794
4. Schaid D.J. The complex genetic epidemiology of prostate cancer. Hum Mol Genet 13 (2004) R103-R121
5. Sun J., Turner A., Xu J., et al. Genetic variability in inflammation pathways and prostate cancer risk. Urol Oncol 25 (2007) 250-259
6. Amundadottir L.T., Sulem P., Gudmundsson J., et al. A common variant associated with prostate cancer in European and African populations. Nat Genet 38 (2006) 652-658
7. Freedman M.L., Haiman C.A., Patterson N., et al. Admixture mapping identifies 8q24 as a prostate cancer risk locus in African-American men. Proc Natl Acad Sci USA 103 (2006) 14068-14073
8. Gudmundsson J., Sulem P., Manolescu A., et al. Genome-wide association study identifies a second prostate cancer susceptibility variant at 8q24. Nat Genet 39 (2007) 631-637
9. Haiman C.A., Patterson N., Freedman M.L., et al. Multiple regions within 8q24 independently affect risk for prostate cancer. Nat Genet 39 (2007) 638-644
10. Yeager M., Orr N., Hayes R.B., et al. Genome-wide association study of prostate cancer identifies a second risk locus at 8q24. Nat Genet 39 (2007) 645-649
11. Schumacher F.R., Feigelson H.S., Cox D.G., et al. A common 8q24 variant in prostate and breast cancer from a large nested case-control study. Cancer Res 67 (2007) 2951-2956
12. Severi G., Hayes V.M., Padilla E.J., et al. The common variant rs1447295 on chromosome 8q24 and prostate cancer risk: results from an Australian population-based case-control study. Cancer Epidemiol Biomarkers Prev 16 (2007) 610-612
13. Suuriniemi M., Agalliu I., Schaid D.J., et al. Confirmation of a positive association between prostate cancer risk and a locus at chromosome 8q24. Cancer Epidemiol Biomarkers Prev 16 (2007) 809-814
14. Wang L., McDonnell S.K., Slusser J.P., et al. Two common chromosome 8q24 variants are associated with increased risk for prostate cancer. Cancer Res 67 (2007) 2944-2950
15. Easton D.F., Pooley K.A., Dunning A.M., et al. A genome-wide association study identifies novel breast cancer susceptibility loci. Nature 447 (2007) 1087-1093
16. Machtens S., Baumann R., Hagemann J., et al. Long-term results of interstitial brachytherapy (LDR-Brachytherapy) in the treatment of patients with prostate cancer. World J Urol 24 (2006) 289-295
17. Meyer A., Wilhelm B., Dörk T., et al. ATM missense variant P1054R predisposes to prostate cancer. Radiother Oncol 83 (2007) 283-288
18. Fletcher O., Johnson N., Gibson L., et al. Association of genetic variants at 8q24 with breast cancer risk. Cancer Epidemiol Biomarkers Prev 17 (2008) 702-705
19. Ribeiro F.R., Jerónimo C., Henrique R., et al. 8q Gain is an independent predictor of poor survival in diagnostic needle biopsies from prostate cancer suspects. Clin Cancer Res 12 (2006) 3961-3970
20. Flaig T.W., Nordeen S.K., Lucia M.S., et al. Conference report and review: Current status of biomarkers potentially associated with prostate cancer outcomes. J Urol 177 (2007) 1229-1237