What Evidence Supports the Use of Computerized Alerts and Prompts to Improve Clinicians' Prescribing Behavior?

Journal of the American Medical Informatics Association

Volumn 16, Issue 4, 2009, Pages 531-538

  Schedlbauer, Angela ^a   Prasad, Vibhore ^a   Mulvaney, Caroline ^a   Phansalkar, Shobha ^b,c,d   Stanton, Wendy ^a   Bates, David W ^b,c,d   Avery, Anthony J ^a  

^a UNIVERSITY OF NOTTINGHAM   (United Kingdom)

^b BRIGHAM AND WOMEN S HOSPITAL   (United States)

^c HARVARD MEDICAL SCHOOL   (United States)

^d PARTNERS HEALTHCARE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; CLINICAL PRACTICE; COMPUTER; COMPUTER SYSTEM; COST BENEFIT ANALYSIS; HEALTH CARE MANAGEMENT; HEALTH PERSONNEL ATTITUDE; HEALTH SERVICE; MEDICAL DECISION MAKING; MEDICAL ERROR; MEDICAL INFORMATION SYSTEM; OUTCOME ASSESSMENT; OUTPATIENT CARE; PRESCRIPTION;

CLINICAL COMPETENCE; DECISION SUPPORT SYSTEMS, CLINICAL; DRUG THERAPY, COMPUTER-ASSISTED; ELECTRONIC PRESCRIBING; HUMANS; MEDICAL ORDER ENTRY SYSTEMS; MEDICATION ERRORS; MEDICATION SYSTEMS; REMINDER SYSTEMS;

EID: 67649378445     PISSN: 10675027     EISSN: None     Source Type: Journal    
DOI: 10.1197/jamia.M2910     Document Type: Article

References (47)

1. Roughead E.E., Gilbert A.L., Primrose J.G., and Sansom L.N. Drug-related hospital admissions: A review of Australian studies. Med J Aust 168 8 (1998) 405-408
2. Von Laue N.C., Schwappach D.L.B., and Koeck C.M. The epidemiology of preventable adverse drug events: A review of the literature. Wien Klin Wochenschr 115 12 (2003) 407-415
3. Bates D.W., Cullen D.J., Laird N., et al. Incidence of adverse drug events and potential adverse drug events. Implications for prevention. ADE Prevention Study Group. J Am Med Assoc 274 (1995) 29-34
4. Kuperman G.J., Bobb A., Payne T.H., et al. Medication-related clinical decision support in computerized provider order entry systems: A review. J Am Med Inform Assoc 14 1 (2007) 29-40
5. Miller R.A., Waitman L.R., Chen S., and Rosenbloom S.T. The anatomy of decision support during inpatient care provider order entry (CPOE): Empirical observations from a decade of CPOE experience at Vanderbilt. J Biomed Inform 38 6 (2005) 469-485
6. Aranow M. What works: Clinical information systems. Order entry rules. Healthcare enterprise achieves physician acceptance, reduced medication errors and improved patient outcomes through CIS and CPOE technology. Health Manag Technol 23 (2002) 34-38
7. Bennett J.W., and Glasziou P.P. Computerised reminders and feedback in medication management: A systematic review of randomised controlled trials. Med J Aust 5 (2003) 217-222
8. Bobb A., Gleason K., Husch M., et al. The epidemiology of prescribing errors: The potential impact of computerized prescriber order entry. Arch Intern Med 164 7 (2004) 785-792
9. Garg A.X., Adhikari N.K.J., McDonald H., et al. Effects of computerized clinical decision support systems on practitioner performance and patient outcomes: A systematic review. JAMA. J Am Med Assoc 293 10 (2005) 1223-1238
10. Hodgkinson B., Koch S., Nay R., and Nichols K. Strategies to reduce medication errors with reference to older adults. Int J Evid Based Healthc 4 (2006) 2-41
11. Kaushal R., Shojania K.G., and Bates D.W. Effects of computerized physician order entry and clinical decision support systems on medication safety: A systematic review. Arch Intern Med 163 (2003) 1409-1416
12. Oren E., Shaffer E.R., and Guglielmo B.J. Impact of emerging technologies on medication errors and adverse drug events. Am J Health Syst Pharm 60 14 (2003) 1447-1458
13. Rabol L.I., Anhoj J., Pedersen A., Pedersen B.L., and Hellebek A.H. Clinical decision support: Is the number of medication errors reduced?. Ugeskr Laeger 168 48 (2006) 4179-4184
14. Van der Sijs H., Aarts J., Vulto A., and Berg M. Overriding of drug safety alerts in computerized physician order entry. J Am Med Inform Assoc 13 2 (2006) 138-147
15. Walton R.T., Harvey E., Dovey S., and Freemantle N. Computerised advice on drug dosage to improve prescribing practice. Cochrane Database Syst Rev (2001) CD002894
16. Higgins J.P.T., and Green S. Formulating the problem. Cochrane Handbook for Systematic Reviews of Interventions 4.2.6. Section 5, 2008. http://www.cochrane.org/resources/handbook/hbook.htm Accessed: May 5, 2008
17. Durieux P., Nizard R., Ravaud P., Mounier N., and Lepage E. Clinical decision support system for prevention of venous thromboembolism: Effect on physician behavior. J Am Med Assoc 283 21 (2000) 2816-2821
18. Martens J.D., Van der W.T., Severens J.L., et al. The effect of computer reminders on GPs' prescribing behaviour: A cluster-randomised trial. Int J Med Inform Suppl 3 (2007) S403-S416
19. Bloomfield H.E., Nelson D.B., van Ryn M., et al. A trial of education, prompts, and opinion leaders to improve prescription of lipid modifying therapy by primary care physicians for patients with ischemic heart disease. Qual Saf Health Care 14 4 (2005) 258-263
20. Cordero L., Kuehn L., Kumar R.R., and Mekhjian H.S. Impact of computerized physician order entry on clinical practice in a newborn intensive care unit. J Perinatol 24 2 (2004) 88-93
21. Hulgan T., Rosenbloom S.T., Hargrove F., et al. Oral quinolones in hospitalized patients: An evaluation of a computerized decision support intervention. J Intern Med 256 4 (2004) 349-357
22. Judge J., Field T.S., DeFlorio M., et al. Prescribers' responses to alerts during medication ordering in the long term care setting. J Am Med Inform Assoc 13 4 (2006) 385-390
23. Shojania K.G., Yokoe D., Platt R., et al. Reducing vancomycin use utilizing a computer guideline: Results of a randomized controlled trial. J Am Med Inform Assoc 5 6 (1998) 554-556
24. Bates D.W., Leape L.L., Cullen D.J., et al. Effect of computerized physician order entry and a team intervention on prevention of serious medication errors. J Am Med Assoc 280 15 (1998) 1311-1316
25. Bates D.W., Teich J.M., Lee J., et al. The impact of computerized physician order entry on medication error prevention. J Am Med Inform Assoc 6 4 (1999) 313-321
26. Galanter W.L., Polikaitis A., and Didomenico R.J. A trial of automated safety alerts for inpatient digoxin use with computerized physician order entry. J Am Med Inform Assoc 11 4 (2004) 270-277
27. Steele A.W., Eisert S., Witter J., et al. The effect of automated alerts on provider ordering behavior in an outpatient setting. PLoS Med 2 9 (2005) 255
28. Teich J.M., Merchia P.R., Schmiz J.L., et al. Effects of computerized physician order entry on prescribing practices. Arch Intern Med 160 (2000) 2741-2747
29. Rind D.M., Safran C., Phillips R.S., et al. Effect of computer-based alerts on the treatment and outcomes of hospitalized patients. Arch Intern Med 154 13 (1994) 1511-1517
30. Peterson J.F., Kuperman G.J., Shek C., et al. Guided prescription of psychotropic medications for geriatric inpatients. Arch Intern Med 165 7 (2005) 802-807
31. Chertow G.M., Lee J., Kuperman G.J., et al. Guided medication dosing for inpatients with renal insufficiency. J Am Med Assoc 286 22 (2001) 2839-2844
32. Clinical Informatics Outcomes Research Group, Bogucki B., Jacobs B.R., and Hingle J. Computerized reminders reduce the use of medications during shortages. J Am Med Inform Assoc 11 4 (2004) 278-280
33. Simon S.R., Smith D.H., Feldstein A.C., et al. Computerized prescribing alerts and group academic detailing to reduce the use of potentially inappropriate medications in older people. J Am Geriatr Soc 54 6 (2006) 963-968
34. Smith D.H., Perrin N., Feldstein A., et al. The impact of prescribing safety alerts for elderly persons in an electronic medical record: An interrupted time series evaluation. Arch Intern Med 166 10 (2006) 1098-1104
35. Agostini J.V., Zhang Y., and Inouye S.K. Use of a computer-based reminder to improve sedative-hypnotic prescribing in older hospitalized patients. J Am Geriatr Soc 55 (2007) 43-48
36. Galanter W.L., Didomenico R.J., and Polikaitis A. A trial of automated decision support alerts for contraindicated medications using computerized physician order entry. J Am Med Inform Assoc 12 3 (2005) 269-274
37. WHO. World Alliance for Patient Safety. http://www.who.int/patientsafety/en/ Accessed: May 5, 2008
38. Shah N.R., Seger A.C., Seger D.L., et al. Improving acceptance of computerized prescribing alerts in ambulatory care. J Am Med Inform Assoc 13 1 (2006) 5-11
39. Avery A.J., Savelyich B.S.P., Sheikh A., et al. Identifying and establishing consensus on the most important safety features of GP computer systems: E-Delphi study. Inform Prim Care 13 1 (2005) 3-11
40. Feldstein A., Simon S.R., Schneider J., et al. How to design computerized alerts to safe prescribing practices. Jt Comm J Qual Saf 30 11 (2004) 602-613
41. Krall M.A., and Sittig D.F. Subjective assessment of usefulness and appropriate presentation mode of alerts and reminders in the outpatient setting. Annual Symposium. Proceedings AMIA (2001) 334-338
42. Glassman P.A., Simon B., Belperio P., and Lanto A. Improving recognition of drug interactions: Benefits and barriers to using automated drug alerts. Med Care 40 12 (2002) 1161-1171
43. Magnus D., Rodgers S., and Avery A.J. GPs. Views on computerized drug interaction alerts: Questionnaire survey. J Clin Pharm Ther 27 5 (2002) 377-382
44. Kawamoto K., Houlihan C.A., Balas E.A., and Lobach D.F. Improving clinical practice using clinical decision support systems: A systematic review of trials to identify features critical to success. BMJ 330 7494 (2005) 765
45. Hellier E., Edworthy J., Derbyshire N., and Costello A. Considering the impact of medicine label design characteristics on patient safety. Ergonomics 49 5-6 (2006) 617-630
46. Center for Information Technology. Leadership (CITL). Report on Ambulatory Computerized Provider Order Entry, ACPOE. http://www.citl.org/research/ACPOE.htm Accessed: Oct 07, 2008
47. Bates D.W., Kuperman G.J., Wang S., et al. Ten commandments for effective clinical decision support: Making the practice of evidence-based medicine a reality. J Am Med Inform Assoc 10 6 (2003) 523-530