Development and validation of an LC-MS/MS method for determination of methanesulfonamide in human urine

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 877, Issue 22, 2009, Pages 2087-2092

  Anacardio, Roberto ^a   Mullins, Frank G P ^b   Hannam, Sally ^b   Sheikh, Muhammed S ^b   O'Shea, Karen ^b   Aramini, Andrea ^a   D'Anniballe, Gaetano ^a   D'Anteo, Loredana ^a   Ferrari, Mauro P ^a   Allegretti, Marcello ^a  

^a Chemistry Section   (Italy)

^b ICON Development Solutions   (United States)

Author keywords

LC MS MS (liquid chromatography mass mass); Methanesulfonamide (MSA); Reparixin; Urine

Indexed keywords

BIOLOGICAL ACTIVITIES; CHROMATOGRAPHIC METHODS; CONCENTRATION RANGES; DERIVATIZATION; DERIVATIZATION PROCEDURES; HUMAN URINE; IN-VIVO; INTERNAL STANDARDS; INTRAVENOUS ADMINISTRATION; LC-MS/MS; LC-MS/MS (LIQUID CHROMATOGRAPHY-MASS/MASS); LOWER LIMIT OF QUANTITATIONS; METHANESULFONAMIDE (MSA); MULTIPLE REACTION MONITORING; REPARIXIN; REVERSED-PHASED HPLC; SPECIFIC INHIBITORS; TANDEM MASS SPECTROMETRY; URINE;

ACETONITRILE; BODY FLUIDS; COLUMN CHROMATOGRAPHY; ELECTROSPRAY IONIZATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HIGH PRESSURE LIQUID CHROMATOGRAPHY; LIQUIDS; MASS SPECTROMETRY;

CHROMATOGRAPHIC ANALYSIS;

ACETONITRILE; CHEMOKINE RECEPTOR ANTAGONIST; DRUG METABOLITE; ETHANESULFONAMIDE; IMIDAZOLE DERIVATIVE; METHANESULFONAMIDE; REPAXIRIN; SULFONAMIDE; UNCLASSIFIED DRUG;

ADULT; ARTICLE; CONTINUOUS INFUSION; CONTROLLED STUDY; DERIVATIZATION; DRUG DETERMINATION; DRUG EXCRETION; DRUG ISOLATION; DRUG STABILITY; DRUG URINE LEVEL; ELECTROSPRAY MASS SPECTROMETRY; HUMAN; LIQUID CHROMATOGRAPHY; LOADING DRUG DOSE; MAINTENANCE DRUG DOSE; MALE; NORMAL HUMAN; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; TANDEM MASS SPECTROMETRY; URINALYSIS; URINARY EXCRETION; VALIDATION PROCESS; VOLUNTEER;

CHROMATOGRAPHY, HIGH PRESSURE LIQUID; HUMANS; INTERLEUKIN-8; SULFONAMIDES; TANDEM MASS SPECTROMETRY;

EID: 67649371449     PISSN: 15700232     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jchromb.2009.05.051     Document Type: Article

References (11)

1. Bertini R., Allegretti M., Bizzarri C., Moriconi A., Locati M., Zampella G., Cervellera M.N., Di Cioccio V., Cesta M.C., Galliera E., Martinez F.O., Di Bitondo R., Troiani G., Sabbatini V., D'Anniballe G., Anacardio R., Cutrin J.C., Cavalieri B., Mainiero F., Strippoli R., Villa P., Di Girolamo M., Martin F., Gentile M., Santoni A., Corda D., Poli G., Mantovani A., Ghezzi P., and Colotta F. Noncompetitive allosteric inhibitors of the inflammatory chemokine receptors CXCR1 and CXCR2: prevention of reperfusion injury. Proc. Natl. Acad. Sci. U.S.A. 101 (2004) 11791
2. Casilli F., Bianchini A., Gloaguen I., Biordi L., Alesse E., Festuccia C., Cavalieri B., Strippoli R., Cervellera M.N., Di Bitondo R., Ferretti E., Mainiero F., Bizzarri C., Colotta F., and Bertini R. Biochem Pharmacol. 69 (2005) 385
3. Falkner F.C. Prostaglandins 24 (1982) 341
4. DeSilva B., Smith W., Weiner R., Kelley M., Smolec J., Lee B., Khan M., Tacey R., Hill H., and Celniker A. Pharm. Res. 20 (2003) 1885
5. Knapp D.R. Handbook of Analytical Derivatization Reactions (1979), John Wiley & Sons, New York
6. Krishnamurthy T., and Sarver E.W. J. Chromatogr. 355 (1986) 253
7. Gorski T., Goehl T.J., Jameson C.W., Collins B.J., Bursey J., and Moseman R. J. Chromatogr. 509 (1990) 383
8. Benington F., Christian S.T., and Morin R.D. J. Chromatogr. 106 (1975) 435
9. Miyazaki H., Ishibashi M., Mori C., and Ikekawa N. Anal. Chem. 46 (1973) 1164
10. Drummond J.T., and Johnson G. Tetrahedron Lett. 29 (1988) 1653
11. Staab H.A. Angew. Chem. Int. Ed. 1 7 (1962) 351 (in English)