HIF-1α inhibition as a novel mechanism of cardiac glycosides in cancer therapeutics

Expert Opinion on Investigational Drugs

Volumn 18, Issue 2, 2009, Pages 241-243

  Lin, Jianqing ^a   Carducci, Michael A ^a  

^a JOHNS HOPKINS UNIVERSITY   (United States)

Author keywords

Cardiac glycosides; Digoxin; HIF 1 inhibition

Indexed keywords

ANTINEOPLASTIC AGENT; CARDIAC GLYCOSIDE; DIGITOXIN; DIGOXIN; HYPOXIA INDUCIBLE FACTOR 1ALPHA; OUABAIN; PROSCILLARIDIN;

ANTINEOPLASTIC ACTIVITY; CANCER CELL; CANCER CHEMOTHERAPY; CLINICAL TRIAL; DRUG SCREENING; DRUG TARGETING; EXPERIMENTAL MODEL; GENE EXPRESSION; HEPATOBLASTOMA; HUMAN; HUMAN CELL CULTURE; IN VIVO STUDY; INHIBITION KINETICS; LYMPHOMA; PHARMACOKINETICS; PROSTATE CANCER; PROTEIN EXPRESSION; PROTEIN SYNTHESIS; REVIEW;

EID: 67649363829     PISSN: 13543784     EISSN: None     Source Type: Journal    
DOI: 10.1517/13543780802683081     Document Type: Review

References (11)

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