Inhibitory effect of zinc on the absorption of β-lactam antibiotic ceftibuten via the peptide transporters in rats

Drug Metabolism and Pharmacokinetics

Volumn 23, Issue 6, 2008, Pages 464-468

  Okamura, Miyako ^a   Terada, Tomohiro ^a   Katsura, Toshiya ^a   Inui, Ken Ichi ^a  

^a KYOTO UNIVERSITY HOSPITAL   (Japan)

Author keywords

Drug interaction; Peptide transporters; Small intestine; Zinc inhibition; lactam antibiotics

Indexed keywords

CEFTIBUTEN; FERROUS SULFATE; PEPTIDE TRANSPORTER 1; ZINC SULFATE;

ANIMAL EXPERIMENT; AREA UNDER THE CURVE; ARTICLE; CONTROLLED STUDY; DRUG ABSORPTION; DRUG BLOOD LEVEL; DRUG POTENTIATION; MALE; MAXIMUM PLASMA CONCENTRATION; NONHUMAN; RAT;

EID: 67649361951     PISSN: 13474367     EISSN: 18800920     Source Type: Journal    
DOI: 10.2133/dmpk.23.464     Document Type: Article

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