Does the apolipoproten E ε4 genotype influence the expression of depression with cognitive impairment?

International Journal of Geriatric Psychiatry

Volumn 24, Issue 6, 2009, Pages 650-652

  Chopra, Mohit P ^a   Landes, Reid D ^b   Jones, Richard A ^c   Feldman, Zach L ^b   Beck, Cornelia ^c   Griffin, Sue T ^c  

^a VETERANS AFFAIRS MEDICAL CENTER   (United States)

^b UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES   (United States)

^c UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

APOLIPOPROTEIN E4;

ALZHEIMER DISEASE; COGNITIVE DEFECT; DEPRESSION; GENE FREQUENCY; GENETIC ASSOCIATION; GENOTYPE; GERIATRIC DEPRESSION SCALE; HUMAN; LETTER; MAJOR DEPRESSION; MILD COGNITIVE IMPAIRMENT; MINI MENTAL STATE EXAMINATION; NEUROPSYCHIATRIC INVENTORY QUESTIONNAIRE; PHENOTYPE; PSYCHOSIS; QUESTIONNAIRE; SELF REPORT; SYMPTOMATOLOGY; AGED; FEMALE; GENETICS; PSYCHOLOGICAL ASPECT;

AGED; AGED, 80 AND OVER; ALZHEIMER DISEASE; APOLIPOPROTEIN E4; DEPRESSIVE DISORDER; FEMALE; HUMANS;

EID: 67649360154     PISSN: 08856230     EISSN: 10991166     Source Type: Journal    
DOI: 10.1002/gps.2217     Document Type: Letter

References (5)

1. Chopra MP, Sullivan J, Feldman Z, et al. 2008. Self-, collateral- and clinician assessment of depression in persons with cognitive impairment. Aging Mental Health 12: 675-683.
2. Muller-Thomsen T, Arlt S, Ganzer S, et al. 2002. Depression in Alzheimer's disease might be associated with apolipoprotein E epsilon 4 allele frequency in women but not in men. Dement Geriatr Cogn Disord 14: 59-63.
3. Pritchard AL, Harris J, Pritchard CW, et al. 2007. The effect of the apolipoprotein E gene polymorphisms and haplotypes on behavioural and psychological symptoms in probable Alzheimer's disease. J Neurol Neurosurg Psychiatry 78: 123-126.
4. Smith GE, Bohac DL, Waring SC, et al. 1998. Apolipoprotein E genotype influences cognitive 'phenotype' in patients with Alzheimer's disease but not in healthy control subjects. Neurology 50: 355-362.
5. Zdanys KF, Kleiman TG, MacAvoy MG, et al. 2007. Apolipoprotein E epsilon4 allele increases risk for psychotic symptoms in Alzheimer's disease. Neuropsychopharmacol 32: 171-179.