The butyrylcholinesterase knockout mouse a research tool in the study of drug sensitivity, bio-distribution, obesity and Alzheimer's disease

Expert Opinion on Drug Metabolism and Toxicology

Volumn 5, Issue 5, 2009, Pages 523-528

  Duysen, Ellen G ^a   Li, Bin ^a   Lockridge, Oksana ^a  

^a UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

Author keywords

Blood brain barrier; Butyrylcholinesterase; Donepezil; Huperzine A; Knockout mouse model; Obesity; Succinylcholine

Indexed keywords

ACETYLCHOLINE; ACETYLCHOLINESTERASE; BAMBUTEROL; CARBOXYLESTERASE; CHOLINESTERASE; COCAINE; DONEPEZIL; HUPERZINE A; ORGANOPHOSPHATE PESTICIDE; SUXAMETHONIUM; TERBUTALINE;

ALZHEIMER DISEASE; ASTHMA; BLOOD BRAIN BARRIER; DETOXIFICATION; DRUG DISTRIBUTION; DRUG SENSITIVITY; ENZYME ACTIVITY; ENZYME DEFICIENCY; GENE FREQUENCY; GENE MUTATION; HUMAN; HYDROLYSIS; KNOCKOUT MOUSE; LIPID DIET; LIPID METABOLISM; LIVER TOXICITY; NONHUMAN; OBESITY; PHENOTYPE; REVIEW;

ACETYLCHOLINESTERASE; ALZHEIMER DISEASE; ANIMALS; BUTYRYLCHOLINESTERASE; CARBOXYLESTERASE; DISEASE MODELS, ANIMAL; HUMANS; MICE; MICE, KNOCKOUT; OBESITY; PHARMACEUTICAL PREPARATIONS; PHENOTYPE; SPECIES SPECIFICITY;

MUS;

EID: 67649322217     PISSN: 17425255     EISSN: None     Source Type: Journal    
DOI: 10.1517/17425250902915555     Document Type: Review

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