Tie2-mediated multidrug resistance in malignant gliomas is associated with upregulation of ABC transporters

Oncogene

Volumn 28, Issue 24, 2009, Pages 2358-2363

  Martin, V ^a   Xu, J ^a   Pabbisetty, S K ^a   Alonso, M M ^a   Liu, D ^a   Lee, O H ^a   Gumin, J ^a   Bhat, K P ^a   Colman, H ^a   Lang, F F ^a   Fueyo, J ^a   Gomez Manzano, C ^a  

^a UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

Author keywords

ABC transporters; Brain tumor stem cells; Chemoresistance; Gliomas; Tie2

Indexed keywords

7 ETHYL 10 HYDROXYCAMPTOTHECIN; ABC TRANSPORTER; ANGIOPOIETIN 1; ANGIOPOIETIN RECEPTOR; BREAST CANCER RESISTANCE PROTEIN; CISPLATIN; DOXORUBICIN; MITOXANTRONE; SMALL INTERFERING RNA;

ARTICLE; CANCER CELL CULTURE; CONTROLLED STUDY; CYTOTOXICITY; GENE ACTIVATION; GENE SILENCING; GENETIC ASSOCIATION; GLIOBLASTOMA; HUMAN; HUMAN CELL; MULTIDRUG RESISTANCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; STEM CELL; UPREGULATION;

ANTINEOPLASTIC AGENTS; ATP-BINDING CASSETTE TRANSPORTERS; BLOTTING, WESTERN; CAMPTOTHECIN; CELL LINE, TUMOR; CELL SURVIVAL; CISPLATIN; DOSE-RESPONSE RELATIONSHIP, DRUG; DOXORUBICIN; DRUG RESISTANCE, MULTIPLE; DRUG RESISTANCE, NEOPLASM; GENE EXPRESSION REGULATION, NEOPLASTIC; GLIOMA; HUMANS; INHIBITORY CONCENTRATION 50; MITOXANTRONE; MULTIDRUG RESISTANCE-ASSOCIATED PROTEINS; NEOPLASM PROTEINS; RECEPTOR, TIE-2; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, SMALL INTERFERING; TRANSFECTION; UP-REGULATION;

EID: 67649286658     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/onc.2009.103     Document Type: Article

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