Non-invasive liver iron concentration measurement by MRI: Comparison of two validated protocols

European Journal of Radiology

Volumn 71, Issue 1, 2009, Pages 116-121

  Olthof, Allard W ^b   Sijens, Paul E ^a   Kreeftenberg, Herman G ^a   Kappert, Peter ^a   van der Jagt, Eric J ^a   Oudkerk, Matthijs ^a  

^a UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

^b Bethesda Hospital   (Netherlands)

Author keywords

Iron concentration; Liver; MRI

Indexed keywords

GRADIENT ECHO SEQUENCES; IRON CONCENTRATION; IRON CONCENTRATIONS; MRI; NON-INVASIVE; NON-INVASIVE ASSESSMENTS; PRE-SELECTION; SPIN ECHO;

CONCENTRATION (PROCESS); MAGNETIC RESONANCE IMAGING;

LIVER;

IRON;

ADULT; ARTICLE; CONTROLLED STUDY; FATTY LIVER; FEMALE; HEMOCHROMATOSIS; HETEROZYGOSITY; HOMOZYGOSITY; HUMAN; HYPERFERRITINEMIA; LIVER CANCER; LIVER PRESERVATION; MAJOR CLINICAL STUDY; MALE; NUCLEAR MAGNETIC RESONANCE IMAGING; PORPHYRIA CUTANEA TARDA; PRIORITY JOURNAL; SIGNAL NOISE RATIO; VALIDATION STUDY;

ADULT; ALGORITHMS; HUMANS; IMAGE ENHANCEMENT; IMAGE INTERPRETATION, COMPUTER-ASSISTED; IRON; LIVER; MAGNETIC RESONANCE IMAGING; MAGNETIC RESONANCE SPECTROSCOPY; MIDDLE AGED; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; TISSUE DISTRIBUTION; YOUNG ADULT;

EID: 67649229562     PISSN: 0720048X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejrad.2008.02.008     Document Type: Article

References (12)

1. Alustiza J.M., Artetxe J., Castiella A., et al. MR quantification of hepatic iron concentration. Radiology 230 (2004) 479-484
2. Bonkovsky H.L. Hepatic iron concentration: noninvasive estimation by means of MR imaging techniques. Radiology 212 (1999) 227-234
3. Olthof A.W., Sijens P.E., Kreeftenberg H.G., et al. Correlation between serum ferritin levels and liver iron concentration determined by MR imaging: impact of hematologic disease and inflammation. Magn Reson Imaging 25 (2007) 228-231
4. Kreeftenberg Jr. H.G., Mooyaart E.L., Huizenga J.R., Sluiter W.J., and Kreeftenberg Sr. H.G. Quantification of liver iron concentration with magnetic resonance imaging by combining T1-, T2-weighted spin echo sequences and a gradient echo sequence. Neth J Med 56 (2000) 133-137
5. Gandon Y., Olivie D., Guyader D., et al. Non-invasive assessment of hepatic iron stores by MRI. Lancet 363 (2004) 357-362
6. Ernst O. Hepatic iron overload: diagnosis and quantification with MR imaging. AJR, Am J Roentgenol 168 (1997) 1205-1208
7. Rose C., Vandevenne P., Bourgeois E., Cambier N., and Ernst O. Liver iron content assessment by routine and simple magnetic resonance imaging procedure in highly transfused patients. Eur J Haematol 77 (2006) 145-149
8. Ambu R., Crisponi G., Sciot R., et al. Uneven hepatic iron and phosphorus distribution in beta-thalassemia. J Hepatol 23 5 (1995) 544-549
9. Laine F., Reymann J.M., Morel F., et al. Effects of phlebotomy therapy on cytochrome P450 2e1 activity and oxidative stress markers in dysmetabolic iron overload syndrome: a randomized trial. Aliment Pharmacol Ther 24 (2006) 1207-1213
10. Papakonstantinou O., Maris T.G., Kostaridou S., Ladis V., Vasiliadou A., and Gourtsoyiannis N.C. Abdominal lymphadenopathy in beta-thalassemia: MRI features and correlation with liver iron overload and posttransfusion chronic hepatitis C. AJR, Am J Roentgenol 185 (2005) 219-224
11. St Pierre T.G. Noninvasive measurement and imaging of liver iron concentrations using proton magnetic resonance. Blood 105 (2005) 855-861
12. Fung E.B., Fischer R., Pakbaz Z., et al. The new SQUID biosusceptometer at Oakland: first year of experience. Neurol Clin Neurophysiol 2004 (2004) 5