Effect of "Garbha Cintamani Rasa", an Ayurvedic formulation on lipid profile, liver function and kidney function parameters of rat plasma after chronic administration

European Journal of Scientific Research

Volumn 32, Issue 1, 2009, Pages 25-32

  Bulbul Jahan, I ^a   Ullah Obayed, M ^a   Rahaman Azizur, M ^a   Rahman Ashfaqur, K ^a   Paul Kumar, A ^a   Choudhuri, M S K ^a  

^a UNIVERSITY OF DHAKA   (Bangladesh)

Author keywords

Ayurvedic; Garbha Cintamani Rasa; GCM; Kidney function and liver function; Lipid profile

Indexed keywords

EID: 67649220747     PISSN: 1450216X     EISSN: 1450202X     Source Type: Journal    
DOI: None     Document Type: Article

References (40)

1. NCEP(Third Report of the National Cholesterol Educaction Program), 2002. Expert panel on detection, evaluation and treatment of high blood cholesterol in adult (Adult Treatment Panel III) final report. Circulation, 106: 3143-3421.
2. Virella-Lopes, M.F. and G. Virella, 2003. The role of immune and inflammatory processes in the development of macrovascular disease in diabetes. Frontiers Biosc, 8:750-768.
3. Sharma, M. K., A.K. Khare and H. Feroz, 1983. Effect of neem oil on blood glucose levels of normal, hyperglycemic and diabetic animals. Indian Med. Gaz., 117: 380-383.
4. Mironova, M.A., R. L. Klein, G.T. Virella and M.F. Lopes-Virella, 2000. Anti-modified LDL antibodies, LDL-containing immune complexes and susceptibility of LDL to in vitro oxidation in patients with type -2 diabetes. Diabetes, 49:1033-1049.
5. Pepato, M.T., A.M. Baviera, R.C. Vendramini, M.P. Perez, I.C. Kettelhut and I.L. Brunetti, 2003. Cissus sicyoides (Princess wine) in the long term treatment of streptozotocin-diabetic rats. Biotechnol. Applied Biochem., 37:15-20.
6. Pushparaj, P., C.H. Tan and B.K.H. Tan, 2000. Effects of Averrhoa bilimbi leaf extract on blood glucose and lipids in streptozotocin-diabetic rats. J. Ethnopharmacol., 72:69-76.
7. Ross, R. N., 1999. Atherosclerosis - An Inflammatory Disease. Eng. J. Med., 340: 115-126.
8. Eidi, A., M. Eidi and E. Esmaeili, 2006. Antidiabetic effect of garlic (Allium sativum L.) in normal and streptozotocin-diabetic rats. Phytomedicine, 13 (9-10): 624-629.
9. Gebhardt, R. and H. Beck, 1996. Differential inhibitory effects of garlic-derived organosulfur compounds on cholesterol biosynthesis in primary rat hepatocyte cultures. Lipids, 31(12):1269-1276.
10. Lee, K.T., I.C. Sohn, D.H. Kim, J.W. Choi, S.H. Kwon and H.J. Park, 2000. Hypoglycemic and hypolipidemic effects of tectorigenin and kaikasaponin III in the streptozotocin-induced diabetic rat and their antioxidant activity in vitro. Arch. Pharm. Res., 23: 461-466.
11. JFZilva, P. R. Panmall and P. D. Mayne, (1991). Clinical Chemistry in Diagnosis and Treatment, England Clays Ltd., St. Ives Plc., England, 5th edition. ISBN: 0713145420
12. Plummer, D.T. (1971). An Introduction to Practical Biochemistry. McGraw-Hill, London, 2nd edn, pp: 144-145. ISBN: 0070941629
13. Kaplan, A.P. 1965. Urea nitrogen and urinary ammonia. In: Standard Method of Clinical Chemistry, Meites S., Academic Press Inc., New York, pp: 245 - 256.
14. nd edn; pp: 1354 - 1374. ISBN: 0721656102
15. King, P.R.N. and E. J. King, 1954. Estimation of Plasma Phosphatase by Determination of Hydrolysed Phenol with Amino-antipyrine, J. Clin. Path. 7(4): 322-326. PMCID: PMC1023845
16. Doumas, B.T., W. A. Watson and H. G. Biggs, 1971. Albumin standards and measurement of serum-albumin with bromocresol green. Clin. Chim. Acta. 31(1): 87- 96. DOI: 10.1016/0009-8981(71)90365-2
17. Friedewald, W.T., R.I. Levy and D.S. Fredrickson, 1972. Estimation of the concentration of Low-Density Lipoprotein Cholesterol in plasma, without use of the preparative ultracentrifuge, Clinical Chemistry, 18(6): 499-502.
18. Evelyn, K.A. and H. T. Malloy, 1938. Microdetermination of Oxyhemoglobin, Methemoglobin, and Sulfhemoglobin in a single sample of Blood. J. Biol. Chem. 126, 655 - 662. Online ISSN 1083-351X, Print ISSN 0021-9258.
19. Glasnapp, D.R. and J.P. Poggio (1985). Essentials of Statistical Analysis for the Behavioral Sciences. Charles E. Merrill Publishing Company, London. ISBN: 0675203694.
20. Naganna, B. 1989. Plasma proteins. In: Textbook of Biochemistry and Human Biology, Talwar G. P., Srivastava L. M. and Moudgil, K. D., Prentice- Hall of India Private Ltd., New- Delhi, 2nd edn.; pp: 59 - 61. ISBN: 8120319656
21. Shahjahan, M., K. E. Sabitha, J. M. and C. S. Shyamala-Devi, 2004. Effect of Solanum trilobatum against carbon tetrachloride induced hepatic damage in albino rats, Indian J. Med. Res, 120: 194-198.
22. Wright, P.J. and D. T. Plummer, 1974. The use of urinary enzyme measurement to detect renal damage caused by nephrotoxic compounds. Biochem. Pharmacol., 23(1): 65-73. DOI: 10.1016/0006-2952(74)90314-1
23. Mitchell, F.L., V. N. and R. W. E. Watts, 1972. Renal function tests suitable for clinical practice. Ann. Clin. Biochem. 9, 1- 20.
24. Kumar, A., A. G. C. Nair, A. V. R. Reddy and A. N. Garg, 2006. Unique ayurvedic metallicherbal preparations, chemical characterization, Biological Trace Element Research, 109: 231-254. doi:10.1385/BTER:109:3:231
25. 2 -induced anemia in rats, Indian J Pharm Sci (69) 6;791-795.
26. Tripathi, Y. B., V.P. Singh. 1996. Role of Tamra bhasma, an Ayurvedic preparation, in the management of lipid peroxidation in liver of albino rats. Indian-J-Exp-Biol. 34(1): 66-7
27. Singh, G., P. Marimuthu, C.S. De-Heluani and C. Catalan, 2004. Antimicrobial and Antioxidant Potentials of Essential Oil and Acetone Extract of Myristica fragrans Houtt. (Aril Part, Journal of Food Science, 70 (2); M141 - M148. DOI: 10.1111/j.1365-2621.2005.tb07105.x
28. Olaleye, M.T., A. C. Akinmoladun and A.A. Akindahunsi, 2006. Antioxidant properties of Myristica fragrans (Houtt) and its effect on selected organs of albino rats. African Journal of Biotechnology, 5(13);1274-127
29. Adaikan, P.G., k. Gauthaman, R.N. Prasad and S.C. Ng, 2000. Proerectile pharmacological effects of Tribulus terrestris extract on the rabbit corpus cavernosum. Ann Acad Med Singapore. 29(1):22-6. PMID: 10748960
30. K. Gauthaman, K., P. G. Adaikan and R. N. V. Prasad, 2002. Aphrodisiac properties of Tribulus Terrestris extract (Protodioscin) in normal and castrated rats, Life Sciences, 71(12);1385-1396. doi:10.1016/S0024-3205(02)01858-1
31. Wang, Y., K. Ohtani, R. Kasai and K. Yamasaki, 1997. Steroidal saponins from fruits of Tribulus terrestris, Phytochemistry, 45(4);811-817. doi:10.1016/S0031-9422(97)00043-5
32. Gautam, M., S. Diwanay, S. Gairola, Y. Shinde, P. Patki and B. Patwardhan, 2004. Immunoadjuvant potential of Asparagus racemosus aqueous extract in experimental systemJournal of Ethnopharmacology, 91(2-3); 251-255. doi:10.1016/j.jep.2003.12.023
33. Sairam, K., S. Priyambada, N. C. Aryya and R. K., 2003. GoelGastroduodenal ulcer protective activity of Asparagus racemosus: an experimental, biochemical and histological study. Journal of Ethnopharmacology. 86(1);1-10. doi:10.1016/S0378-8741(02)00342-2
34. Jayashree, P. K., K.K. Boloor, T.P.A. Devasagayam and S. R. Venkatachalam, 2000. Antioxidant properties of Asparagus racemosus against damage induced by γ-radiation in rat liver mitochondria, Journal of Ethnopharmacology, 71(3); 425-435. doi:10.1016/S0378-8741(00)00176-8
35. Wiboonpun, N., P. Phuwapraisirisan, S. Tip-pyang, 2004. Identification of antioxidant compound from Asparagus racemosus, Phytotherapy Research 18(9); 771 - 773. DOI: 10.1002/ptr.1526
36. Franzotti, E.M., C. V. F. Santos, H. M. S. L. Rodrigues, R. H. V. Mourão, M. R. Andrade and A. R. Antoniolli, 2000. Anti-inflammatory, analgesic activity and acute toxicity of Sida cordifolia L. (Malva-branca), Journal of Ethnopharmacology 72(1-2); 273-277 doi:10.1016/S0378-8741(00)00205-1
37. Ahmed, M., S. Amin, M. Islam, M. Takahashi, E. Okuyama and C.F. Hossain, 2000. Analgesic principle from Abutilon indicum, Pharmazie. 2000 Apr;55(4):314-6. PMID: 10798248
38. E Porchezhian, E. and S.H. Ansari, 2005. Hepatoprotective activity of on experimental liver damage in rats. Phytomedicine, 12 (1 - 2); 62 - 64.
39. Seetharam, Y.N., G. Chalageri, S. R. Setty and Bheemachar, 2002. Hypoglycemic activity of Abutilon indicum leaf extracts in rats, Fitoterapia, 73(2);156-159. doi:10.1016/S0367-326X(02)00015-1.
40. Cho S.Y., J.Y. Park, E.M. Park, M.S. Choi, M.Y. Lee, S.M. Joen, M.K. Jang, M.J. Kim and Y.B. Park, 2002. Alternation of hepatic antioxidant enzyme activities and lipid profile in streptozotocin -induced diabetic rats by supplementation of dandelion water extract, Clin. Chem. Acta, 317: 109-117.