Usefulness of gemcitabine combined with 5-fluorouracil and cisplatin (GFP) in patients for unresectable biliary carcinoma

Hepato-Gastroenterology

Volumn 56, Issue 90, 2009, Pages 307-312

  Morine, Yuji ^a   Shimada, Mitsuo ^a   Ikegami, Torn ^a   Imura, Satoru ^a   Kanemura, Hirohumi ^a   Arakawa, Yusuke ^a   Hanaoka, Jun ^a   Kanamoto, Mami ^a   Nii, Akira ^a  

^a UNIVERSITY OF TOKUSHIMA   (Japan)

Author keywords

Biliary carcinoma; Combined chemotherapy; Gemcitabine

Indexed keywords

CISPLATIN; FLUOROURACIL; GEMCITABINE; UFT;

ADULT; AGED; ANEMIA; ANOREXIA; ARTICLE; BILE DUCT CARCINOMA; BILIARY TRACT CANCER; CANCER COMBINATION CHEMOTHERAPY; CANCER REGRESSION; CLINICAL ARTICLE; DEATH; DIARRHEA; DRUG EFFICACY; DRUG WITHDRAWAL; FATIGUE; FEMALE; GALLBLADDER CANCER; HEMATOLOGIC DISEASE; HUMAN; INOPERABLE CANCER; LEUKOPENIA; MALE; MULTIPLE CYCLE TREATMENT; NAUSEA; PRIORITY JOURNAL; SIDE EFFECT; THROMBOCYTOPENIA; TREATMENT OUTCOME;

ADULT; AGED; AGED, 80 AND OVER; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; BILE DUCT NEOPLASMS; CHI-SQUARE DISTRIBUTION; CISPLATIN; DEOXYCYTIDINE; FEMALE; FLUOROURACIL; GALLBLADDER NEOPLASMS; HUMANS; MALE; MIDDLE AGED; STATISTICS, NONPARAMETRIC; SURVIVAL RATE; TREATMENT OUTCOME;

EID: 67649213198     PISSN: 01726390     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (17)

1. Ministry and Health, Labour and Welfare: Statistics and Information Department, Minister's Secretariat, Ministry of Health, Labour and Welfare. Vital Statistics of Japan 2004 (in Japanease).
2. Alexander F, Rossi RL, O'Bryan M, Khettry U, Braasch JW, Watkins E Jr: Binary carcinoma. A review of 109 cases. Am J Surg. 1984; 147: 503-509.
3. Oertli D, Herzog U, Tondelli P: Primary carcinoma of the gallbladder: operative experience during a 16 year period. Eur J Surg. 1993; 159: 415-420.
4. Wade TP, Prasad CN, Virgo KS, Johnson FE: Experience with distal bile duct cancers in U.S. Veterans Affairs hospitals: 1987-1991. J Surg Oncol. 1997; 64: 242-245.
5. de Groen PC, Gores GJ, LaRusso NF, Gunderson LL, Nagorney DM: Biliary tract cancers. N Engl J Med. 1999 Oct 28; 341: 1368-1378.
6. Pichlmayr R, Lamesch P, Weimann A, Tusch G, Ringe B: Surgical treatment of cholangiocellular carcinoma. World J Surg. 1995; 19: 83-88.
7. Valverde A, Bonhomme N, Farges O, Sauvanet A, Fle-jou JF, Belghiti J: Resection of intrahepatic cholangiocar-cinoma: a Western experience. J Hepatobiliary Pancreat Surg. 1999; 6: 122-127.
8. Kaye SB: Gemcitabine: current status of phase I and II tri-als.J Clin Oncol. 1994; 12:1527-1531.
9. Burris HA 3rd, Moore MJ, Andersen J, Green MR, Rothenberg ML, Modiano MR, Cripps MC, Portenoy RK, Storniolo AM, Tarassoff P, Nelson R, Dorr FA, Stephens CD, Von Hoff DD: Improvements in survival and clinical benefit with gemcitabine as first-line therapy for patients with advanced pancreas cancer: a randomized trial. J Clin Oncol. 1997; 15:2403-2413.
10. Okusaka T, Ishii H, Funakoshi A, Yamao K, Ohkawa S, Saito S, Saito H, Tsuyuguchi T: Phase II study of sin-gle-agent gemcitabine in patients with advanced biliary tract cancer. Cancer Chemother Pharmacol. 2006; 57: 647-653.
11. Crino L, Scagliotti G, Marangolo M, Figoli F, Clerici M, De Marinis F, Salvati F, Cruciani G, Dogliotti L, Pucci F, Paccagnella A, Adamo V, Altavilla G, Incoro-nato P, Trippetti M, Mosconi AM, Santucci A, Sor-bolini S, Oliva C, Tonato M: Cisplatin-gemcitabine combination in advanced non-small-cell lung cancer: a phase U study. J Clin Oncol. 1997; 15: 297-303.
12. Byrne MJ, Davidson JA, Musk AW, Dewar J, van Hazel G, Buck M, de Klerk NH, Robinson BW: Cisplatin and gemcitabine treatment for malignant mesothe-lioma: a phase II study. J Clin Oncol. 1999; 17: 25-30.
13. Kanzawa F, Saijo N: In vitro interaction between gemcitabine and other anticancer drugs using a novel three-dimensional model. Semin Oncol. 1997; 24(2 Suppl 7): S7.
14. Schurz L, Schalhorn A, Wilmanns W: Synergic interaction of gemcitabine and 5-fluorouracil in colon cancer cells. Proc Am Soc Clin Oncol 1998 (abstr 965).
15. Hidalgo M, Castellano D, Paz-Ares L, Gravalos C, Diaz-Puente M, Hitt R, Alonso S, Cortes-Funes H: Phase I-II study of gemcitabine and fluorouracil as a continuous infusion in patients with pancreatic cancer. J Clin Oncol. 1999; 17: 585-592.
16. Yamashita Y, Taketomi A, Fukuzawa K, Yoshizumi T, Uchiyama H, Simada M, Shirabe K, Wakasugi K, Mae-hara Y: Gemcitabine combined with 5-fluorouracil and cisplatin (GFP) in patients with advanced biliary tree cancers: a pilot study. Anticancer Res. 2006; 26: 771-775.
17. Peters GJ, Ruiz van Haperen VW, Bergman AM, Veerman G, Smitskamp-Wilms E, van Moorsel CJ, Kuiper CM, Braakhuis BJ: Preclinical combination therapy with gemcitabine and mechanisms of resistance. Semin