Proof of concept for the reduction of classical swine fever infection in pigs by a novel viral polymerase inhibitor

Journal of General Virology

Volumn 90, Issue 6, 2009, Pages 1335-1342

  Vrancken, Robert ^a   Haegeman, Andy ^a   Paeshuyse, Jan ^b   Puerstinger, Gerhard ^c   Rozenski, Jef ^b   Wright, Matthew ^d   Tignon, Marylène ^a   Le Potier, Marie Frédérique ^e   Neyts, Johan ^b   Koenen, Frank ^a  

^a VETERINARY AND AGROCHEMICAL RESEARCH CENTRE   (Belgium)

^b REGA INSTITUTE FOR MEDICAL RESEARCH   (Belgium)

^c UNIVERSITY OF INNSBRUCK   (Austria)

^d GILEAD SCIENCES   (United States)

^e Healthy Pigs Production and Experimentation Section   (France)

Author keywords

[No Author keywords available]

Indexed keywords

5 [(4 BROMOPHENYL)METHYL] 2 PHENYL 5H IMIDAZO[4,5 C]PYRIDINE; IMIDAZO[4,5 C]PYRIDINE DERIVATIVE; UNCLASSIFIED DRUG; VIRUS RNA; 5 ((4 BROMOPHENYL)METHYL) 2 PHENYL 5H IMIDAZO(4,5 C)PYRIDINE; 5-((4-BROMOPHENYL)METHYL)-2-PHENYL-5H-IMIDAZO(4,5-C)PYRIDINE; ANTIVIRUS AGENT; IMIDAZOLE DERIVATIVE; PYRIDINE DERIVATIVE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; DRUG EFFICACY; DRUG POTENCY; DRUG TOLERABILITY; INFECTION CONTROL; LEUKOPENIA; MAXIMUM PLASMA CONCENTRATION; NONHUMAN; PRIORITY JOURNAL; SEROCONVERSION; SINGLE DRUG DOSE; SWINE DISEASE; TIME TO MAXIMUM PLASMA CONCENTRATION; TONSIL; VETERINARY MEDICINE; VIREMIA; VIRUS GENOME; VIRUS INHIBITION; VIRUS ISOLATION; VIRUS LOAD; VIRUS NEUTRALIZATION; ANIMAL; DRUG EFFECT; ORAL DRUG ADMINISTRATION; PALATINE TONSIL; PESTIVIRUS; SWINE; VIROLOGY;

ANIMALIA; CLASSICAL SWINE FEVER VIRUS; SUIDAE;

ADMINISTRATION, ORAL; ANIMALS; ANTIVIRAL AGENTS; CLASSICAL SWINE FEVER; CLASSICAL SWINE FEVER VIRUS; IMIDAZOLES; LEUKOPENIA; PALATINE TONSIL; PYRIDINES; SWINE; VIRAL LOAD; VIREMIA;

EID: 67649199351     PISSN: 00221317     EISSN: 14652099     Source Type: Journal    
DOI: 10.1099/vir.0.008839-0     Document Type: Article

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