-
1
-
-
0036598992
-
Targeting death and decoy receptors of the tumour-necrosis factor superfamily
-
Ashkenazi A. Targeting death and decoy receptors of the tumour-necrosis factor superfamily. Nat. Rev. Cancer 2 (2002) 420-430
-
(2002)
Nat. Rev. Cancer
, vol.2
, pp. 420-430
-
-
Ashkenazi, A.1
-
2
-
-
34249663310
-
Targeting death-inducing receptors in cancer therapy
-
Takeda K., Stagg J., Yagita H., Okumura K., and Smyth M.J. Targeting death-inducing receptors in cancer therapy. Oncogene 26 (2007) 3745-3757
-
(2007)
Oncogene
, vol.26
, pp. 3745-3757
-
-
Takeda, K.1
Stagg, J.2
Yagita, H.3
Okumura, K.4
Smyth, M.J.5
-
3
-
-
0033667778
-
FADD/MORT1 and caspase-8 are recruited to TRAIL receptors 1 and 2 and are essential for apoptosis mediated by TRAIL receptor 2
-
Sprick M.R., Weigand M.A., Rieser E., Rauch C.T., Juo P., Blenis J., Krammer P.H., and Walczak H. FADD/MORT1 and caspase-8 are recruited to TRAIL receptors 1 and 2 and are essential for apoptosis mediated by TRAIL receptor 2. Immunity 12 (2000) 599-609
-
(2000)
Immunity
, vol.12
, pp. 599-609
-
-
Sprick, M.R.1
Weigand, M.A.2
Rieser, E.3
Rauch, C.T.4
Juo, P.5
Blenis, J.6
Krammer, P.H.7
Walczak, H.8
-
4
-
-
0035860696
-
Modulation of tumor necrosis factor apoptosis-inducing ligand- induced NF-kappa B activation by inhibition of apical caspases
-
Harper N., Farrow S.N., Kaptein A., Cohen G.M., and MacFarlane M. Modulation of tumor necrosis factor apoptosis-inducing ligand- induced NF-kappa B activation by inhibition of apical caspases. J. Biol. Chem. 276 (2001) 34743-34752
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 34743-34752
-
-
Harper, N.1
Farrow, S.N.2
Kaptein, A.3
Cohen, G.M.4
MacFarlane, M.5
-
5
-
-
0033662433
-
Apo2L/TRAIL-dependent recruitment of endogenous FADD and caspase-8 to death receptors 4 and 5
-
Kischkel F.C., Lawrence D.A., Chuntharapai A., Schow P., Kim K.J., and Ashkenazi A. Apo2L/TRAIL-dependent recruitment of endogenous FADD and caspase-8 to death receptors 4 and 5. Immunity 12 (2000) 611-620
-
(2000)
Immunity
, vol.12
, pp. 611-620
-
-
Kischkel, F.C.1
Lawrence, D.A.2
Chuntharapai, A.3
Schow, P.4
Kim, K.J.5
Ashkenazi, A.6
-
6
-
-
3442895056
-
CD95 death-inducing signaling complex formation and internalization occur in lipid rafts of type I and type II cells
-
Eramo A., Sargiacomo M., Ricci-Vitiani L., Todaro M., Stassi G., Messina C.G., Parolini I., Lotti F., Sette G., Peschle C., and De Maria R. CD95 death-inducing signaling complex formation and internalization occur in lipid rafts of type I and type II cells. Eur. J. Immunol. 34 (2004) 1930-1940
-
(2004)
Eur. J. Immunol.
, vol.34
, pp. 1930-1940
-
-
Eramo, A.1
Sargiacomo, M.2
Ricci-Vitiani, L.3
Todaro, M.4
Stassi, G.5
Messina, C.G.6
Parolini, I.7
Lotti, F.8
Sette, G.9
Peschle, C.10
De Maria, R.11
-
7
-
-
33644858084
-
The role of receptor internalization in CD95 signaling
-
Lee K.H., Feig C., Tchikov V., Schickel R., Hallas C., Schutze S., Peter M.E., and Chan A.C. The role of receptor internalization in CD95 signaling. EMBO J. 25 (2006) 1009-1023
-
(2006)
EMBO J.
, vol.25
, pp. 1009-1023
-
-
Lee, K.H.1
Feig, C.2
Tchikov, V.3
Schickel, R.4
Hallas, C.5
Schutze, S.6
Peter, M.E.7
Chan, A.C.8
-
8
-
-
0029868036
-
A physical interaction between the cell death protein Fas and the tyrosine kinase p59fynT
-
Atkinson E.A., Ostergaard H., Kane K., Pinkoski M.J., Caputo A., Olszowy M.W., and Bleackley R.C. A physical interaction between the cell death protein Fas and the tyrosine kinase p59fynT. J. Biol. Chem. 271 (1996) 5968-5971
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 5968-5971
-
-
Atkinson, E.A.1
Ostergaard, H.2
Kane, K.3
Pinkoski, M.J.4
Caputo, A.5
Olszowy, M.W.6
Bleackley, R.C.7
-
9
-
-
0037815277
-
Fas-associated death domain protein and caspase-8 are not recruited to the tumor necrosis factor receptor 1 signaling complex during tumor necrosis factor-induced apoptosis
-
Harper N., Hughes M., MacFarlane M., and Cohen G.M. Fas-associated death domain protein and caspase-8 are not recruited to the tumor necrosis factor receptor 1 signaling complex during tumor necrosis factor-induced apoptosis. J. Biol. Chem. 278 (2003) 25534-25541
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 25534-25541
-
-
Harper, N.1
Hughes, M.2
MacFarlane, M.3
Cohen, G.M.4
-
10
-
-
0041853690
-
Induction of TNF receptor I-mediated apoptosis via two sequential signaling complexes
-
Micheau O., and Tschopp J. Induction of TNF receptor I-mediated apoptosis via two sequential signaling complexes. Cell 114 (2003) 181-190
-
(2003)
Cell
, vol.114
, pp. 181-190
-
-
Micheau, O.1
Tschopp, J.2
-
11
-
-
4444341939
-
Compartmentalization of TNF receptor 1 signaling: internalized TNF receptosomes as death signaling vesicles
-
Schneider-Brachert W., Tchikov V., Neumeyer J., Jakob M., Winoto-Morbach S., Held-Feindt J., Heinrich M., Merkel O., Ehrenschwender M., Adam D., Mentlein R., Kabelitz D., and Schutze S. Compartmentalization of TNF receptor 1 signaling: internalized TNF receptosomes as death signaling vesicles. Immunity 21 (2004) 415-428
-
(2004)
Immunity
, vol.21
, pp. 415-428
-
-
Schneider-Brachert, W.1
Tchikov, V.2
Neumeyer, J.3
Jakob, M.4
Winoto-Morbach, S.5
Held-Feindt, J.6
Heinrich, M.7
Merkel, O.8
Ehrenschwender, M.9
Adam, D.10
Mentlein, R.11
Kabelitz, D.12
Schutze, S.13
-
12
-
-
34250331231
-
Receptor-mediated endocytosis is not required for tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis
-
Kohlhaas S.L., Craxton A., Sun X.M., Pinkoski M.J., and Cohen G.M. Receptor-mediated endocytosis is not required for tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis. J. Biol. Chem. 282 (2007) 12831-12841
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 12831-12841
-
-
Kohlhaas, S.L.1
Craxton, A.2
Sun, X.M.3
Pinkoski, M.J.4
Cohen, G.M.5
-
13
-
-
33745928465
-
Death-receptor activation halts clathrin-dependent endocytosis
-
Austin C.D., Lawrence D.A., Peden A.A., Varfolomeev E.E., Totpal K., De Maziere A.M., Klumperman J., Arnott D., Pham V., Scheller R.H., and Ashkenazi A. Death-receptor activation halts clathrin-dependent endocytosis. Proc. Natl. Acad. Sci. U. S. A. 103 (2006) 10283-10288
-
(2006)
Proc. Natl. Acad. Sci. U. S. A.
, vol.103
, pp. 10283-10288
-
-
Austin, C.D.1
Lawrence, D.A.2
Peden, A.A.3
Varfolomeev, E.E.4
Totpal, K.5
De Maziere, A.M.6
Klumperman, J.7
Arnott, D.8
Pham, V.9
Scheller, R.H.10
Ashkenazi, A.11
-
14
-
-
0034843322
-
Inhibition of TRAIL-induced apoptosis and forced internalization of TRAIL receptor 1 by adenovirus proteins
-
Tollefson A.E., Toth K., Doronin K., Kuppuswamy M., Doronina O.A., Lichtenstein D.L., Hermiston T.W., Smith C.A., and Wold W.S. Inhibition of TRAIL-induced apoptosis and forced internalization of TRAIL receptor 1 by adenovirus proteins. J. Virol. 75 (2001) 8875-8887
-
(2001)
J. Virol.
, vol.75
, pp. 8875-8887
-
-
Tollefson, A.E.1
Toth, K.2
Doronin, K.3
Kuppuswamy, M.4
Doronina, O.A.5
Lichtenstein, D.L.6
Hermiston, T.W.7
Smith, C.A.8
Wold, W.S.9
-
16
-
-
0031013623
-
Oxidative stress, thiol reagents, and membrane potential modulate the mitochondrial permeability transition by affecting nucleotide binding to the adenine nucleotide translocase
-
Halestrap A.P., Woodfield K.Y., and Connern C.P. Oxidative stress, thiol reagents, and membrane potential modulate the mitochondrial permeability transition by affecting nucleotide binding to the adenine nucleotide translocase. J. Biol. Chem. 272 (1997) 3346-3354
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 3346-3354
-
-
Halestrap, A.P.1
Woodfield, K.Y.2
Connern, C.P.3
-
17
-
-
0037109064
-
Role of critical thiol groups on the matrix surface of the adenine nucleotide translocase in the mechanism of the mitochondrial permeability transition pore
-
McStay G.P., Clarke S.J., and Halestrap A.P. Role of critical thiol groups on the matrix surface of the adenine nucleotide translocase in the mechanism of the mitochondrial permeability transition pore. Biochem. J. 367 (2002) 541-548
-
(2002)
Biochem. J.
, vol.367
, pp. 541-548
-
-
McStay, G.P.1
Clarke, S.J.2
Halestrap, A.P.3
-
18
-
-
0029863399
-
Modulation of the mitochondrial permeability transition pore by pyridine nucleotides and dithiol oxidation at two separate sites
-
Costantini P., Chernyak B.V., Petronilli V., and Bernardi P. Modulation of the mitochondrial permeability transition pore by pyridine nucleotides and dithiol oxidation at two separate sites. J. Biol. Chem. 271 (1996) 6746-6751
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 6746-6751
-
-
Costantini, P.1
Chernyak, B.V.2
Petronilli, V.3
Bernardi, P.4
-
19
-
-
0033378831
-
Interactions of chloromethyltetramethylrosamine (Mitotracker Orange) with isolated mitochondria and intact cells
-
Scorrano L., Petronilli V., Colonna R., Di Lisa F., and Bernardi P. Interactions of chloromethyltetramethylrosamine (Mitotracker Orange) with isolated mitochondria and intact cells. Ann. N.Y. Acad. Sci. 893 (1999) 391-395
-
(1999)
Ann. N.Y. Acad. Sci.
, vol.893
, pp. 391-395
-
-
Scorrano, L.1
Petronilli, V.2
Colonna, R.3
Di Lisa, F.4
Bernardi, P.5
-
20
-
-
0021997899
-
Evidence for the involvement of vicinal sulfhydryl groups in insulin-activated hexose transport by 3T3-L1 adipocytes
-
Frost S.C., and Lane M.D. Evidence for the involvement of vicinal sulfhydryl groups in insulin-activated hexose transport by 3T3-L1 adipocytes. J. Biol. Chem. 260 (1985) 2646-2652
-
(1985)
J. Biol. Chem.
, vol.260
, pp. 2646-2652
-
-
Frost, S.C.1
Lane, M.D.2
-
21
-
-
0025688139
-
Tyrosine phosphorylation in T cells is regulated by phosphatase activity: studies with phenylarsine oxide
-
Garcia-Morales P., Minami Y., Luong E., Klausner R.D., and Samelson L.E. Tyrosine phosphorylation in T cells is regulated by phosphatase activity: studies with phenylarsine oxide. Proc. Natl. Acad. Sci. U. S. A. 87 (1990) 9255-9259
-
(1990)
Proc. Natl. Acad. Sci. U. S. A.
, vol.87
, pp. 9255-9259
-
-
Garcia-Morales, P.1
Minami, Y.2
Luong, E.3
Klausner, R.D.4
Samelson, L.E.5
-
22
-
-
0025860032
-
Phosphotyrosyl turnover in insulin signaling. Characterization of two membrane-bound pp15 protein tyrosine phosphatases from 3T3-L1 adipocytes
-
Liao K., Hoffman R.D., and Lane M.D. Phosphotyrosyl turnover in insulin signaling. Characterization of two membrane-bound pp15 protein tyrosine phosphatases from 3T3-L1 adipocytes. J. Biol. Chem. 266 (1991) 6544-6553
-
(1991)
J. Biol. Chem.
, vol.266
, pp. 6544-6553
-
-
Liao, K.1
Hoffman, R.D.2
Lane, M.D.3
-
23
-
-
0022343333
-
A comparison of catecholamine-induced internalization of beta-adrenergic receptors and receptor-mediated endocytosis of epidermal growth factor in human astrocytoma cells. Inhibition by phenylarsine oxide
-
Hertel C., Coulter S.J., and Perkins J.P. A comparison of catecholamine-induced internalization of beta-adrenergic receptors and receptor-mediated endocytosis of epidermal growth factor in human astrocytoma cells. Inhibition by phenylarsine oxide. J. Biol. Chem. 260 (1985) 12547-12553
-
(1985)
J. Biol. Chem.
, vol.260
, pp. 12547-12553
-
-
Hertel, C.1
Coulter, S.J.2
Perkins, J.P.3
-
24
-
-
0021846764
-
Phenylarsine oxide-induced increase in alveolar macrophage surface receptors: evidence for fusion of internal receptor pools with the cell surface
-
Kaplan J., Ward D.M., and Wiley H.S. Phenylarsine oxide-induced increase in alveolar macrophage surface receptors: evidence for fusion of internal receptor pools with the cell surface. J. Cell. Biol. 101 (1985) 121-129
-
(1985)
J. Cell. Biol.
, vol.101
, pp. 121-129
-
-
Kaplan, J.1
Ward, D.M.2
Wiley, H.S.3
-
25
-
-
0037192790
-
Bcl-2 and Bcl-xL inhibit CD95-mediated apoptosis by preventing mitochondrial release of Smac/DIABLO and subsequent inactivation of X-linked inhibitor-of-apoptosis protein
-
Sun X.M., Bratton S.B., Butterworth M., MacFarlane M., and Cohen G.M. Bcl-2 and Bcl-xL inhibit CD95-mediated apoptosis by preventing mitochondrial release of Smac/DIABLO and subsequent inactivation of X-linked inhibitor-of-apoptosis protein. J. Biol. Chem. 277 (2002) 11345-11351
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 11345-11351
-
-
Sun, X.M.1
Bratton, S.B.2
Butterworth, M.3
MacFarlane, M.4
Cohen, G.M.5
-
26
-
-
0033582526
-
Distinct caspase cascades are initiated in receptor-mediated and chemical-induced apoptosis
-
Sun X.M., MacFarlane M., Zhuang J., Wolf B.B., Green D.R., and Cohen G.M. Distinct caspase cascades are initiated in receptor-mediated and chemical-induced apoptosis. J. Biol. Chem. 274 (1999) 5053-5060
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 5053-5060
-
-
Sun, X.M.1
MacFarlane, M.2
Zhuang, J.3
Wolf, B.B.4
Green, D.R.5
Cohen, G.M.6
-
27
-
-
0030770614
-
Identification and molecular cloning of two novel receptors for the cytotoxic ligand TRAIL
-
MacFarlane M., Ahmad M., Srinivasula S.M., Fernandes-Alnemri T., Cohen G.M., and Alnemri E.S. Identification and molecular cloning of two novel receptors for the cytotoxic ligand TRAIL. J. Biol. Chem. 272 (1997) 25417-25420
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 25417-25420
-
-
MacFarlane, M.1
Ahmad, M.2
Srinivasula, S.M.3
Fernandes-Alnemri, T.4
Cohen, G.M.5
Alnemri, E.S.6
-
28
-
-
0001197832
-
Emerging families of cytokines and receptors
-
Bazan J.F. Emerging families of cytokines and receptors. Curr. Biol. 3 (1993) 603-606
-
(1993)
Curr. Biol.
, vol.3
, pp. 603-606
-
-
Bazan, J.F.1
-
29
-
-
0034613295
-
Crystal structure of TRAIL-DR5 complex identifies a critical role of the unique frame insertion in conferring recognition specificity
-
Cha S.S., Sung B.J., Kim Y.A., Song Y.L., Kim H.J., Kim S., Lee M.S., and Oh B.H. Crystal structure of TRAIL-DR5 complex identifies a critical role of the unique frame insertion in conferring recognition specificity. J. Biol. Chem. 275 (2000) 31171-31177
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 31171-31177
-
-
Cha, S.S.1
Sung, B.J.2
Kim, Y.A.3
Song, Y.L.4
Kim, H.J.5
Kim, S.6
Lee, M.S.7
Oh, B.H.8
-
30
-
-
0032750511
-
Structure of the TRAIL-DR5 complex reveals mechanisms conferring specificity in apoptotic initiation
-
Mongkolsapaya J., Grimes J.M., Chen N., Xu X.N., Stuart D.I., Jones E.Y., and Screaton G.R. Structure of the TRAIL-DR5 complex reveals mechanisms conferring specificity in apoptotic initiation. Nat. Struct. Biol. 6 (1999) 1048-1053
-
(1999)
Nat. Struct. Biol.
, vol.6
, pp. 1048-1053
-
-
Mongkolsapaya, J.1
Grimes, J.M.2
Chen, N.3
Xu, X.N.4
Stuart, D.I.5
Jones, E.Y.6
Screaton, G.R.7
-
31
-
-
37849032983
-
The conformation of the extracellular binding domain of Death Receptor 5 in the presence and absence of the activating ligand TRAIL: a molecular dynamics study
-
Wassenaar T.A., Quax W.J., and Mark A.E. The conformation of the extracellular binding domain of Death Receptor 5 in the presence and absence of the activating ligand TRAIL: a molecular dynamics study. Proteins 70 (2008) 333-343
-
(2008)
Proteins
, vol.70
, pp. 333-343
-
-
Wassenaar, T.A.1
Quax, W.J.2
Mark, A.E.3
-
32
-
-
10644296258
-
The C-terminal tails of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) and Fas receptors have opposing functions in Fas-associated death domain (FADD) recruitment and can regulate agonist-specific mechanisms of receptor activation
-
Thomas L.R., Johnson R.L., Reed J.C., and Thorburn A. The C-terminal tails of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) and Fas receptors have opposing functions in Fas-associated death domain (FADD) recruitment and can regulate agonist-specific mechanisms of receptor activation. J. Biol. Chem. 279 (2004) 52479-52486
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 52479-52486
-
-
Thomas, L.R.1
Johnson, R.L.2
Reed, J.C.3
Thorburn, A.4
-
33
-
-
35748975398
-
TRAIL signals to apoptosis in chronic lymphocytic leukaemia cells primarily through TRAIL-R1 whereas cross-linked agonistic TRAIL-R2 antibodies facilitate signalling via TRAIL-R2
-
Natoni A., MacFarlane M., Inoue S., Walewska R., Majid A., Knee D., Stover D.R., Dyer M.J., and Cohen G.M. TRAIL signals to apoptosis in chronic lymphocytic leukaemia cells primarily through TRAIL-R1 whereas cross-linked agonistic TRAIL-R2 antibodies facilitate signalling via TRAIL-R2. Br. J. Haematol. 139 (2007) 568-577
-
(2007)
Br. J. Haematol.
, vol.139
, pp. 568-577
-
-
Natoni, A.1
MacFarlane, M.2
Inoue, S.3
Walewska, R.4
Majid, A.5
Knee, D.6
Stover, D.R.7
Dyer, M.J.8
Cohen, G.M.9
-
34
-
-
21744448694
-
Chronic lymphocytic leukemic cells exhibit apoptotic signaling via TRAIL-R1
-
MacFarlane M., Inoue S., Kohlhaas S.L., Majid A., Harper N., Kennedy D.B., Dyer M.J., and Cohen G.M. Chronic lymphocytic leukemic cells exhibit apoptotic signaling via TRAIL-R1. Cell. Death Differ. 12 (2005) 773-782
-
(2005)
Cell. Death Differ.
, vol.12
, pp. 773-782
-
-
MacFarlane, M.1
Inoue, S.2
Kohlhaas, S.L.3
Majid, A.4
Harper, N.5
Kennedy, D.B.6
Dyer, M.J.7
Cohen, G.M.8
-
35
-
-
57749097095
-
TRAIL resistance of breast cancer cells is associated with constitutive endocytosis of death receptors 4 and 5
-
Zhang Y., and Zhang B. TRAIL resistance of breast cancer cells is associated with constitutive endocytosis of death receptors 4 and 5. Mol. Cancer Res. 6 (2008) 1861-1871
-
(2008)
Mol. Cancer Res.
, vol.6
, pp. 1861-1871
-
-
Zhang, Y.1
Zhang, B.2
|