The abbreviated impactor measurement (AIM) concept: Part II - Influence of evaporation of a volatile component - Evaluation with a "droplet-producing" pressurized metered dose inhaler (pMDI)-based formulation containing ethanol as cosolvent

AAPS PharmSciTech

Volumn 10, Issue 1, 2009, Pages 252-257

  Mitchell, J P ^a   Nagel, M W ^a   Avvakoumova, V ^a   MacKay, H ^a   Ali, R ^a  

^a TRUDELL MEDICAL INTERNATIONAL   (Canada)

Author keywords

Cascade impactor; Inhaler testing; Particle evaporation; Particle size distribution

Indexed keywords

ALCOHOL; BECLOMETASONE DIPROPIONATE; FLUTICASONE PROPIONATE; NORFLURANE; PROPELLANT; VOLATILE ORGANIC COMPOUND; ANTIASTHMATIC AGENT; BECLOMETASONE; SOLVENT;

ABBREVIATED IMPACTOR MEASUREMENT; AEROSOL; ANDERSEN NONVIABLE CASCADE IMPACTOR; ARTICLE; CONTROLLED STUDY; COPLEY FAST SCREENING ANDERSEN IMPACTOR; DRUG COATING; DRUG FORMULATION; EVAPORATION; INTERMETHOD COMPARISON; METERED DOSE INHALER; PARTICLE SIZE; TRUDELL FAST SCREENING ANDERSEN IMPACTOR; CHEMISTRY; EQUIPMENT DESIGN; INHALATIONAL DRUG ADMINISTRATION; INSTRUMENTATION; MATERIALS TESTING; PHARMACEUTICS; PRESSURE; REPRODUCIBILITY; VALIDATION STUDY; VOLATILIZATION;

ADMINISTRATION, INHALATION; AEROSOLS; ANTI-ASTHMATIC AGENTS; BECLOMETHASONE; CHEMISTRY, PHARMACEUTICAL; EQUIPMENT DESIGN; ETHANOL; MATERIALS TESTING; METERED DOSE INHALERS; PARTICLE SIZE; PRESSURE; REPRODUCIBILITY OF RESULTS; SOLVENTS; TECHNOLOGY, PHARMACEUTICAL; VOLATILIZATION;

EID: 67549149797     PISSN: None     EISSN: 15309932     Source Type: Journal    
DOI: 10.1208/s12249-009-9201-x     Document Type: Article

References (16)

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