Polymer-magnesium aluminum silicate composite dispersions for improved physical stability of acetaminophen suspensions

AAPS PharmSciTech

Volumn 10, Issue 2, 2009, Pages 346-354

  Pongjanyakul, Thaned ^a   Puttipipatkhachorn, Satit ^b  

^a KHON KAEN UNIVERSITY   (Thailand)

^b MAHIDOL UNIVERSITY   (Thailand)

Author keywords

Magnesium aluminum silicate; Physical stability; Sodium alginate; Sodium carboxymethylcellose; Suspensions

Indexed keywords

ALGINIC ACID; ATTAPULGITE; CARBOXYMETHYLCELLULOSE; ETHER; METHYLCELLULOSE; PARACETAMOL; ALUMINUM DERIVATIVE; GLUCURONIC ACID; HEXURONIC ACID; MAGNESIUM DERIVATIVE; POLYMER; SILICATE;

ARTICLE; CHEMICAL STRUCTURE; CONTROLLED STUDY; DISPERSION; DRUG FORMULATION; DRUG SOLUBILITY; DRUG STABILITY; FLOCCULATION; INTERMETHOD COMPARISON; MICROSCOPY; PARTICLE SIZE; PHYSICAL CHEMISTRY; PHYSICAL PHASE; SUSPENSION; THIXOTROPY; VISCOSITY; ZETA POTENTIAL; CHEMISTRY; SOLUBILITY;

ACETAMINOPHEN; ALGINATES; ALUMINUM COMPOUNDS; CARBOXYMETHYLCELLULOSE; DRUG STABILITY; FLOCCULATION; GLUCURONIC ACID; HEXURONIC ACIDS; MAGNESIUM COMPOUNDS; METHYLCELLULOSE; PARTICLE SIZE; POLYMERS; SILICATES; SOLUBILITY; SUSPENSIONS;

EID: 67549145147     PISSN: None     EISSN: 15309932     Source Type: Journal    
DOI: 10.1208/s12249-009-9215-4     Document Type: Article

References (27)

1. Zatz JL, Berry JJ, Alderman DA. Viscosity-imparting agents in diperse systems. In: Lieberman HA, Rieger MM, Banker GS, editors. Pharmaceutical dosage forms: Disperse systems, vol. 19. New York: Marcel Dekker; 1989. p. 171-203.
2. Martin A. Physical pharmacy. 4th ed. Philadelphia: Lea & Febiger; 1993.
3. Viseras C, Aguzzi C, Cerezo P, Lopez-Galindo A. Uses of clay minerals in semisolid health care and therapeutic products. Appl Clay Sci. 2007;36:37-50.
4. Kibbe HA. Handbook of pharmaceutical excipients. 3rd ed. Washington: American Pharmaceutical Association; 2000.
5. Grim RE. Clay mineralogy. New York: McGraw-Hill Book Company; 1953. p. 43-83.
6. Alexandre M, Dubois P. Polymer-layered silicate nanocomposites: preparation, properties and uses of a new class of materials. Mater Sci Eng. 2000;28:1-63.
7. Gupta MK, Vanwert A, Bogner RH. Formation of physical stable amorphous drugs by milling with Neusilin. J Pharm Sci. 2003;92:536-51.
8. Zatz JL, Kushla GP. Gels. In: Lieberman HA, Rieger MM, Banker GS, editors. Pharmaceutical dosage forms: Disperse systems, vol. 19. New York: Marcel Dekker; 1989. p. 495-510.
9. Ciullo PA. Rheological properties of magnesium aluminum silicate/xanthan gum dispersions. J Soc Cosmet Chem. 1981;32:275-85.
10. Ciullo PA, Braun DB. Clay/carbomer mixtures enhance emulsion stability. Cosmet Toilet. 1991;106:89-95.
11. Pongjanyakul T, Priprem A, Puttipipatkhachorn S. Influence of magnesium aluminium silicate on rheological, release and permeation characteristics of diclofenac sodium aqueous gels in-vitro. J Pharm Pharmacol. 2005;57:429-34.
12. Pongjanyakul T, Puttipipatkhachorn S. Sodium alginate-magnesium aluminum silicate composite gels: Characterization of flow behavior, microviscosity, and drug diffusivity. AAPS PharmSciTech. 2007;8:E158-65.
13. Attama AA, Adikwu MU, Esimone CO. Sedimentation studies on chalk suspensions containing blends of Veegum and detarium gum as suspending agents. Boll Chim Farm. 1999;138:521-5.
14. Khunawattanakul W, Puttipipatkhachorn S, Rades T, Pongjanyakul T. Chitosan-magnesium aluminum silicate composite dispersions: characterization of rheology, flocculate size and zeta potential. Int J Pharm. 2008;351:227-35.
15. Yoon SY, Deng Y. Flocculation and reflocculation of clay suspension by different polymer systems under turbulent conditions. J Colloid Interface Sci. 2004;278:139-45.
16. Addai-Mensak J. Enhanced flocculation and dewatering of clay mineral dispersions. Powder Technol. 2007;179:73-8.
17. Kamibayashi M, Ogura H, Otsubo Y. Shear-thickening flow of nanoparticle suspension flocculated by polymer bridging. J Colloid Interface Sci. 2008;321:294-301.
18. Ziller KH, Rupprecht H. Control of crystal growth in drug suspensions. 1. Design of a control unit and application to acetaminophen suspensions. Drug Dev Ind Pharm. 1988;14:2341-70.
19. US Pharmacopeia 29, Asian Edition. United States Pharmacopeia Convention Inc., Rockville, 2006. p. 3420.
20. Di Martino P, Guyot-Hermann A-M, Conflant P, Drache M, Guyot J-C. A new pure paracetamol for direct compression: The orthorhombic form. Int J Pharm. 1996;128:1-8.
21. Ledru J, Imrie CT, Pulham CR, Céolin R, Hutchinson JM. High pressure differential scanning calorimetry investigations on the pressure dependence of the melting of paracetamol polymorphs I and II. J Pharm Sci. 2007;96:2784-94.
22. Torrado JJ, Illum L, Davis SS. Particle size and size distribution of albumin microspheres produced by heat and chemical stabilization. Int J Pharm. 1989;51:85-93.
23. Tempio JS, Zatz JL. Flocculation effect of xanthan gum in pharmaceutical suspensions. J Pharm Sci. 1980;69:1209-14.
24. Junyaprasert VB, Manwiwattanakul G. Release profile comparison and stability of diltiazem-resin microcapsules in sustained release suspensions. Int J Pharm. 2008;352:81-91.
25. Ogger KE, Noory C, Gabay J, Shah VP, Skelly JP. Dissolution profiles of resin-based oral suspensions. Pharm Technol. 1991;9:84-91.
26. Wen H, Morris KR, Park K. Hydrogen bonding interactions between adsorbed polymer molecules and crystal surface of acetaminophen. J Colloid Interface Sci. 2005;290:325-35.
27. Draget KI. Alginates. In: Philips GO, Williams PA, editors. Handbook of hydrocolloids. Cambridge: Woodhead; 2000. p. 379-95.