Screening and prediction of reactive intermediates in a microreactor with immobilized rat hepatic microsomes using acetaminophen as a model drug

Enzyme and Microbial Technology

Volumn 45, Issue 2, 2009, Pages 112-117

  Tanvir, Shazia ^a   Adenier, Hervé ^a   Pulvin, Sylviane ^a  

^a UNIVERSITÉ DE TECHNOLOGIE DE COMPIÈGNE   (France)

Author keywords

Biosensor; Immobilization; mGST; Microreactor; Microsome; P450; Reactive intermediate

Indexed keywords

IMMOBILIZATION; MGST; MICROREACTOR; MICROSOME; P450; REACTIVE INTERMEDIATE;

ENZYMES; SIGNAL TRANSDUCTION;

BIOSENSORS;

DRUG METABOLITE; GLUTATHIONE; GLUTATHIONE TRANSFERASE; PARACETAMOL;

ANIMAL CELL; ARTICLE; BIOSENSOR; CONTROLLED STUDY; DRUG METABOLISM; DRUG SCREENING; ENZYME ACTIVITY; ENZYME MEMBRANE BIOREACTOR; LIVER MICROSOME; MALE; NONHUMAN; RAT;

RATTUS;

EID: 67549137230     PISSN: 01410229     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.enzmictec.2009.05.006     Document Type: Article

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