Pretreatment with erythropoietin reduces hepatic ischemia-reperfusion injury

Hepatobiliary and Pancreatic Diseases International

Volumn 8, Issue 3, 2009, Pages 294-299

  Luo, Yu Hong ^a   Li, Zheng Dong ^a   Liu, Li Xin ^a   Dong, Gao Hong ^a  

^a JINAN UNIVERSITY   (China)

Author keywords

Erythropoietin; Heme oxygenase 1; Ischemia reperfusion injury

Indexed keywords

ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; ERYTHROPOIETIN; HEME OXYGENASE 1; PLACEBO;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; CONTROLLED STUDY; DRUG MECHANISM; HISTOPATHOLOGY; LAPAROTOMY; LIVER FUNCTION; LIVER ISCHEMIA; MALE; NONHUMAN; PROTEIN EXPRESSION; RAT; REPERFUSION INJURY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

ALANINE TRANSAMINASE; ANIMALS; ASPARTATE AMINOTRANSFERASES; BLOTTING, WESTERN; ERYTHROPOIETIN; HEME OXYGENASE-1; HEPATECTOMY; LIVER; MALE; POSTOPERATIVE PERIOD; PREOPERATIVE CARE; RATS; RATS, SPRAGUE-DAWLEY; REPERFUSION INJURY; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; UP-REGULATION;

EID: 67549129092     PISSN: 14993872     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (28)

1. Brines M, Cerami A. Emerging biological roles for erythropoietin in the nervous system. Nat Rev Neurosci 2005;6:484-494. (Pubitemid 40769173)
2. Sepodes B, Maio R, Pinto R, Sharples E, Oliveira P, McDonald M, et al. Recombinant human erythropoietin protects the liver from hepatic ischemia-reperfusion injury in the rat. Transpl Int 2006;19:919-926. (Pubitemid 44511117)
3. Sola A, Wen TC, Hamrick SE, Ferriero DM. Potential for protection and repair following injury to the developing brain: a role for erythropoietin? Pediatr Res 2005;57:110R-117R.
4. Lipsic E, van der Meer P, Henning RH, Suurmeijer AJ, Boddeus KM, van Veldhuisen DJ, et al. Timing of erythropoietin treatment for cardioprotection in ischemia/reperfusion. J Cardiovasc Pharmacol 2004;44:473-479. (Pubitemid 39305089)
5. Takahashi T, Morita K, Akagi R, Sassa S. Protective role of heme oxygenase-1 in renal ischemia. Antioxid Redox Signal 2004;6:867-877. (Pubitemid 39237940)
6. Mancuso C, Scapagini G, Currò D, Giuffrida Stella AM, De Marco C, Butterfield DA, et al. Mitochondrial dysfunction, free radical generation and cellular stress response in neurodegenerative disorders. Front Biosci 2007;12:1107-1123. (Pubitemid 46846882)
7. Bayir H, Kochanek PM, Kagan VE. Oxidative stress in immature brain after traumatic brain injury. Dev Neurosci 2006;28:420-431. (Pubitemid 44310508)
8. Shimizu H, Takahashi T, Suzuki T, Yamasaki A, Fujiwara T, Odaka Y, et al. Protective effect of heme oxygenase induction in ischemic acute renal failure. Crit Care Med 2000;28:809-817 (Pubitemid 30174282)
9. Nath KA, Grande JP, Haggard JJ, Croatt AJ, Katusic ZS, Solovey A, et al. Oxidative stress and induction of heme oxygenase-1 in the kidney in sickle cell disease. Am J Pathol 2001;158:893-903. (Pubitemid 32221782)
10. Gueler F, Gwinner W, Schwarz A, Haller H. Long-term effects of acute ischemia and reperfusion injury. Kidney Int 2004;66:523-527. (Pubitemid 38981991)
11. Blydt-Hansen TD, Katori M, Lassman C, Ke B, Coito AJ, Iyer S, et al. Gene transfer-induced local heme oxygenase-1 overexpression protects rat kidney transplants from ischemia/reperfusion injury. J Am Soc Nephrol 2003;14:745-754. (Pubitemid 36246020)
12. Baan C, Peeters A, Lemos F, Uitterlinden A, Doxiadis I, Claas F, et al. Fundamental role for HO-1 in the self-protection of renal allografts. Am J Transplant 2004;4:811-818. (Pubitemid 38637582)
13. Nath KA. Heme oxygenase-1: a redoubtable response that limits reperfusion injury in the transplanted adipose liver. J Clin Invest 1999;104:1485-1486. (Pubitemid 30002356)
14. Ono K, Goto Y, Takagi S, Baba S, Tago N, Nonogi H, et al. A promoter variant of the heme oxygenase-1 gene may reduce the incidence of ischemic heart disease in Japanese. Atherosclerosis 2004;173:315-319.
15. Bahlmann FH, Song R, Boehm SM, Mengel M, von Wasielewski R, Lindschau C, et al. Low-dose therapy with the long-acting erythropoietin analogue darbepoetin alpha persistently activates endothelial Akt and attenuates progressive organ failure. Circulation 2004;110:1006-1012. (Pubitemid 39128626)
16. Carlini RG, Reyes AA, Rothstein M. Recombinant human erythropoietin stimulates angiogenesis in vitro. Kidney Int 1995;47:740-745.
17. Haller H, Christel C, Dannenberg L, Thiele P, Lindschau C, Luft FC. Signal transduction of erythropoietin in endothelial cells. Kidney Int 1996;50:481-488. (Pubitemid 26274375)
18. Ribatti D, Presta M, Vacca A, Ria R, Giuliani R, Dell'Era P, et al. Human erythropoietin induces a pro-angiogenic phenotype in cultured endothelial cells and stimulates neovascularization in vivo. Blood 1999;93:2627-2636. (Pubitemid 29181195)
19. Calvillo L, Latini R, Kajstura J, Leri A, Anversa P, Ghezzi P, et al. Recombinant human erythropoietin protects the myocardium from ischemia-reperfusion injury and promotes beneficial remodeling. Proc Natl Acad Sci U S A 2003;100:4802-4806. (Pubitemid 36457809)
20. Cerami A, Brines M, Ghezzi P, Cerami C, Itri LM. Neuroprotective properties of epoetin alfa. Nephrol Dial Transplant 2002;17:8-12. (Pubitemid 34157113)
21. Chong ZZ, Kang JQ, Maiese K. Erythropoietin is a novel vascular protectant through activation of Akt1 and mitochondrial modulation of cysteine proteases. Circulation 2002;106:2973-2979. (Pubitemid 35424751)
22. Nath KA, Katusic ZS, Gladwin MT. The perfusion paradox and vascular instability in sickle cell disease. Microcirculation 2004;11:179-193. (Pubitemid 39619078)
23. Beschorner R, Adjodah D, Schwab JM, Mittelbronn M, Pedal I, Mattern R, et al. Long-term expression of heme oxygenase-1 (HO-1, HSP-32) following focal cerebral infarctions and traumatic brain injury in humans. Acta Neuropathol 2000;100:377-384. (Pubitemid 30497006)
24. Calò LA, Stanic L, Davis PA, Pagnin E, Munaretto G, Fusaro M, et al. Effect of epoetin on HO-1 mRNA level and plasma antioxidants in hemodialysis patients. Int J Clin Pharmacol Ther 2003;41:187-192. (Pubitemid 36603760)
25. Burger D, Xiang F, Hammoud L, Lu X, Feng Q. Role of heme oxygenase-1 in the cardioprotective effects of erythropoietin during myocardial ischemia and reperfusion. Am J Physiol Heart Circ Physiol 2009;296:H84-93.
26. Kacimi R, Chentoufi J, Honbo N, Long CS, Karliner JS. Hypoxia differentially regulates stress proteins in cultured cardiomyocytes: role of the p38 stress-activated kinase signaling cascade, and relation to cytoprotection. Cardiovasc Res 2000;46:139-150. (Pubitemid 30155954)
27. Pachori AS, Smith A, McDonald P, Zhang L, Dzau VJ, Melo LG. Heme-oxygenase-1-induced protection against hypoxia/reoxygenation is dependent on biliverdin reductase and its interaction with PI3K/Akt pathway. J Mol Cell Cardiol 2007;43:580-592. (Pubitemid 47615045)
28. Alcaraz MJ, Vicente AM, Araico A, Dominguez JN, Terencio MC, Ferrándiz ML. Role of nuclear factor-kappaB and heme oxygenase-1 in the mechanism of action of an anti-inflammatory chalcone derivative in RAW 264.7 cells. Br J Pharmacol 2004;142:1191-1199. (Pubitemid 39093016)