Protective effect of heme oxygenase induction in ischemic acute renal failure

Critical Care Medicine

Volumn 28, Issue 3, 2000, Pages 809-817

  Shimizu, Hiroko ^a   Takahashi, Toru ^a   Suzuki, Tsutomu ^a   Yamasaki, Akira ^a   Fujiwara, Tadao ^a   Odaka, Yasuo ^a   Hirakawa, Masahisa ^a   Fujita, Hiroyoshi ^b   Akagi, Reiko ^c  

^a OKAYAMA UNIVERSITY MEDICAL SCHOOL   (Japan)

^b HOKKAIDO UNIVERSITY   (Japan)

^c OKAYAMA PREFECTURAL UNIVERSITY   (Japan)

Author keywords

Heat shock protein 70; Heme; Heme oxygenase 1; Ischemic acute renal failure; Oxidative stress; Renal function; Tin mesoporphyrin; aminolevulinate synthase

Indexed keywords

5 AMINOLEVULINATE SYNTHASE; CREATININE; HEAT SHOCK PROTEIN 70; HEME OXYGENASE; MESOPORPHYRIN TIN;

ACUTE KIDNEY FAILURE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL DAMAGE; CELL PROTECTION; CONTROLLED STUDY; CREATININE BLOOD LEVEL; ENZYME ACTIVITY; ENZYME INDUCTION; ENZYME INHIBITION; GENE EXPRESSION; KIDNEY ISCHEMIA; MALE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; RAT;

EID: 0034066305     PISSN: 00903493     EISSN: None     Source Type: Journal    
DOI: 10.1097/00003246-200003000-00033     Document Type: Article

References (59)

1. 1. Bonventre JV: Mechanisms of ischemic acute renal failure. Kidney Int 1993; 43:1160-1178
2. 2. Racusen LC: The histopathology of acute renal failure. New Horiz 1995; 3:662-668
3. 3. McCord JM: Oxygen-derived free radicals in postischemic tissue injury. N Engl J Med 1985; 312:159-163
4. 4. Paller MS, Hoidal JR, Ferris TF: Oxygen free radicals in ischemic acute renal failure in the rat. J Clin Invest 1984; 74:1156-1164
5. 5. Ratych RE, Bulkley GB: Free-radical-mediated postischemic reperfusion injury in the kidney. Free Radical Biol Med 1986; 2:311-319
6. 6. Baker GL, Corry RJ, Autor AP: Oxygen free radical induced damage in kidneys subjected to warm ischemia and reperfusion. Ann Surg 1985; 202:628-641
7. 7. Swann RC, Merrill JP: The clinical course of acute renal failure. Medicine 1953; 32: 215-292
8. 8. Briggs JD, Kennedy AC, Young LN, et al: Renal function after acute tubular necrosis. BMJ 1967; 3:513-516
9. 9. Butkus DE: Persistent high mortality in acute renal failure: Are we asking the right questions? Arch Intern Med 1983; 143: 209-212
10. 10. Brivet FG, Kleinknecht DJ, Loirat P, et al: Acute renal failure in intensive care units: Causes, outcome, and prognostic factors of hospital mortality. A prospective, multicenter study. Crit Care Med 1996; 24: 192-198
11. 11. Emami A, Schwartz JH, Borkan SC: Transient ischemia or heat stress induces a cytoprotectant protein in rat kidney. Am J Physiol 1991; 260:F479-F485
12. 12. Van Why SK, Hildebrandt F, Ardito T, et al: Induction and intracellular localization of HSP-72 after renal ischemia. Am J Physiol 1992; 263:F769-F775
13. 13. Humes HD, Cieslinski DA, Coimbra TM, et al: Epidermal growth factor enhances renal tubule cell regeneration and repair and accelerates the recovery of renal function in postischemic acute renal failure. J Clin Invest 1989; 84:1757-1761
14. 14. Wagener OE, Lieske JC, Toback FG: Molecular and cell biology of acute renal failure: New therapeutic strategies. New Horiz 1995; 3:634-649
15. 15. Johnson JP, Rokaw MD: Experimental acute renal failure. In: Acute Renal Failure in the Critically Ill. Bellomo R, Ronco C (Eds). Berlin, Springer-Verlag, 1995, pp 28-57
16. 16. Shibahara S, Müller RM, Taguchi H: Transcriptional control of rat heme oxygenase by heat shock. J Biol Chem 1987; 262: 12889-12892
17. 17. Keyse SM, Tyrrell RM: Heme oxygenase is the major 32-kDa stress protein induced in human skin fibroblasts by UVA radiation, hydrogen peroxide, and sodium arsenite. Proc Natl Acad Sci U S A 1989; 86:99-103
18. 18. Maines MD, Mayer RD, Ewing JF, et al: Induction of kidney heme oxygenase-1 (HSP32) mRNA and protein by ischemia/ reperfusion: Possible role of heme as both promotor of tissue damage and regulator of HSP32. J Pharmacol Exp Ther 1993; 264: 457-462
19. 19. Schlesinger MJ: Heat shock proteins. J Biol Chem 1990; 265:12111-12114
20. 20. Paller MS, Nath KA, Rosenberg ME: Heme oxygenase is not expressed as a stress protein after renal ischemia. J Lab Clin Med 1993; 122:341-345
21. 21. Riddle RD, Yamamoto M, Engel JD: Expression of δ-aminolevulinate synthase in avian cells: Separate genes encode erythroid-specific and nonspecific isozymes. Proc Natl Acad Sci U S A 1989; 86:792-796
22. 4 vinyl groups of Sn-protoporphyrin to form Sn-mesoporphyrin markedly enhances the ability of the metalloporphyrin to inhibit in vivo heme catabolism. Arch Biochem Biophys 1987; 255: 64-74
23. 23. Valaes T, Petmezaki S, Henschke C, et al: Control of jaundice in preterm newborns by an inhibitor of bilirubin production: Studies with tin-mesoporphyrin. Pediatrics 1994; 93: 1-11
24. 24. Shibahara S, Müller R, Taguchi H, et al: Cloning and expression of cDNA for rat heme oxygenase. Proc Natl Acad Sci U S A 1985; 82:7865-7869
25. 25. Yamamoto M, Kure S, Engel JD, et al: Structure, turnover, and heme-mediated suppression of the level of mRNA encoding rat liver δ-aminolevulinate synthase. J Biol Chem 1988; 263:15973-15979
26. 26. Longo FM, Wang S, Narasimhan P, et al: cDNA cloning and expression of stress-inducible rat hsp70 in normal and injured rat brain. J Neurosci Res 1993; 36:325-335
27. 27. Chirgwin JM, Przybyla AE, MacDonald RJ, et al: Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease. Biochemistry 1979; 18:5294-5299
28. 28. Fujita H, Sassa S: The rapid and decremental change in haem oxygenase mRNA during erythroid differentiation of murine erythroleukaemia cells. Br J Haematol 1989; 73: 557-560
29. 29. Paul KG, Theorell H, Åkeson Å: The molar light absorption of pyridine ferroprotoporphyrin (pyridine haemochromogen). Acta Chem Scand 1953; 7:1284-1287
30. 30. Berry EA, Trumpower BL: Simultaneous determination of hemes a, b, and c from pyridine hemochrome spectra. Anal Biochem 1987; 161:1-15
31. 31. Lowry OH, Rosebrough NJ, Farr AL, et al: Protein measurement with the Folin phenol reagent. J Biol Chem 1951; 193:265-275
32. 32. Tenhunen R, Marver HS, Schmid R: The enzymatic conversion of heme to bilirubin by microsomal heme oxygenase. Proc Natl Acad Sci U S A 1968; 61:748-755
33. 33. Tenhunen R, Marver HS, Schmid R: The enzymatic catabolism of hemoglobin: Stimulation of microsomal heme oxygenase by hemin. J Lab Clin Med 1970; 75:410-421
34. 34. Yamamoto M, Hayashi N, Kikuchi G: Regulation of synthesis and intracellular translocation of δ-aminolevulinate synthase by heme and its regulation to the heme saturation of tryptophan pyrrolase in rat liver. Arch Biochem Biophys 1981; 209:451-459
35. 35. Takeda A, Onodera H, Sugimoto A, et al: Increased expression of heme oxygenase mRNA in rat brain following transient forebrain ischemia. Brain Res 1994; 666: 120-124
36. 36. Katayose D, Isoyama S, Fujita H, et al: Separate regulation of heme oxygenase and heat shock protein 70 mRNA expression in the rat heart by hemodynamic stress. Biochem Biophys Res Commun 1993; 191:587-594
37. 37. Alam J, Shibahara S, Smith A: Transcriptional activation of the heme oxygenase gene by heme and cadmium in mouse hepatoma cells. J Biol Chem 1989; 264:6371-6375
38. 38. Yomogida K, Yamamoto M, Yamagami T, et al: Structure and expression of the gene encoding rat nonspecific form δ-aminolevulinate synthase. J Biochem 1993; 113:364-371
39. 39. Nath KA, Balla G, Vercellotti GM, et al: Induction of heme oxygenase is a rapid, protective response in rhabdomyolysis in the rat. J Clin Invest 1992; 90:267-270
40. 40. Agarwal A, Balla J, Alam J, et al: Induction of heme oxygenase in toxic renal injury. A protective role in cisplatin nephrotoxicity in the rat. Kidney Int 1995; 48:1298-1307
41. 41. Orrenius S, Ellin Å, Jakobsson SV, et al: The cytochrome P-450-containing mono-oxygenase system of rat kidney cortex microsomes. Drug Metab Dispos 1973; 1:350-357
42. 42. Roberts BJ, Shoaf SE, Jeong KS, et al: Induction of CYP2E1 in liver, kidney, brain and intestine during chronic ethanol administration and withdrawal: Evidence that CYP2E1 possesses a rapid phase half-life of 6 hours or less. Biochem Biophys Res Commun 1994; 205:1064-1071
43. 43. Tamura Y, Imaoka S, Gemba M, et al: Effects of ischemia-reperfusion on individual cytochrome P450 isoforms in the rat kidney. Life Sci 1997; 60:143-149
44. 44. Paller MS, Jacob HS: Cytochrome P-450 mediates tissue-damaging hydroxyl radical formation during reoxygenation of the kidney. Proc Natl Acad Sci U S A 1994; 91:7002-7006
45. 45. Sassa S: Recent progress in heme synthesis and metabolism. In: Regulation of Heme Protein Synthesis. Fujita H (Ed). Dayton, OH, Alpha Med Press, 1994, pp 1-10
46. 46. Balla J, Jacob HS, Balla G, et al: Endothelial-cell heme uptake from heme proteins: Induction of sensitization and desensitization to oxidant damage. Proc Natl Acad Sci U S A 1993; 90:9285-9289
47. 47. Zager RA, Burkhart KM, Conrad DS, et al: Iron, heme oxygenase, and glutathione: Effects on myohemoglobinuric proximal tubular injury. Kidney Int 1995; 48:1624-1634
48. 48. Stocker R: Induction of haem oxygenase as a defence against oxidative stress. Free Radical Res Commun 1990; 9:101-112
49. 49. Vincent SH: Oxidative effects of heme and porphyrins on proteins and lipids. Semin Hematol 1989; 26:105-113
50. 3 segments. Kidney Int 1978; 14:31-49
51. 51. Finn WF, Chevalier RL: Recovery from postischemic acute renal failure in the rat. Kidney Int 1979; 16:113-123
52. 2 after warm ischemia. Am J Physiol 1984; 247: R1047-R1053
53. 53. Vile GF, Basu-Modak S, Waltner C, et al: Heme oxygenase 1 mediates an adaptive response to oxidative stress in human skin fibroblasts. Proc Natl Acad Sci U S A 1994; 91:2607-2610
54. 54. Llesuy SF, Tomaro ML: Heme oxygenase and oxidative stress: Evidence of involvement of bilirubin as physiological protector against oxidative damage. Biochim Biophys Acta 1994; 1223:9-14
55. 55. Dennery PA, Sridhar KJ, Lee CS, et al: Heme oxygenase-mediated resistance to oxygen toxicity in hamster fibroblasts. J Biol Chem 1997; 272:14937-14942
56. 56. Poss KD, Tonegawa S: Heme oxygenase 1 is required for mammalian iron utilization. Proc Natl Acad Sci U S A 1997; 94: 10919-10924
57. 57. Poss KD, Tonegawa S: Reduced stress defense in heme oxygenase 1 deficient cells. Proc Natl Acad Sci U S A 1997; 94: 10925-10930
58. 58. Kappas A, Drummond GS: Control of heme metabolism with synthetic metalloporphyrins. J Clin Invest 1986; 77:335-339
59. 59. Kappas A, Simionatto CS, Drummond GS, et al: The liver excretes large amounts of heme into bile when heme oxygenase is inhibited competitively by Sn-protoporphyrin. Proc Natl Acad Sci U S A 1985; 82:896-900