Mesenchymal stem cells showed the highest potential for the regeneration of injured liver tissue compared with other subpopulations of the bone marrow

Cell Biology International

Volumn 33, Issue 7, 2009, Pages 772-777

  Cho, Kyung Ah ^a   Ju, Sun Young ^a   Cho, Su Jin ^a   Jung, Yun Jae ^b   Woo, So Youn ^a   Seoh, Ju Young ^a   Han, Ho Seong ^c   Ryu, Kyung Ha ^a  

^a Ewha Womans University School of Medicine   (South Korea)

^b Gachon University College of Medicine   (South Korea)

^c Seoul National University College of Medicine   (South Korea)

Author keywords

Liver injury; Mesenchymal stem cells (MSCs); Transplantation

Indexed keywords

GREEN FLUORESCENT PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL DIFFERENTIATION; CELL MIGRATION; CELL SUBPOPULATION; COCULTURE; CONFOCAL MICROSCOPY; CONTROLLED STUDY; ENGRAFTMENT; FEMALE; FLOW CYTOMETRY; FLUORESCENCE ANALYSIS; HEMATOPOIETIC STEM CELL; HEMATOPOIETIC STEM CELL TRANSPLANTATION; INTERMETHOD COMPARISON; LIVER CELL; LIVER INJURY; LIVER REGENERATION; MESENCHYMAL STEM CELL; MESENCHYMAL STEM CELL TRANSPLANTATION; MONONUCLEAR CELL; MOUSE; NONHUMAN; PROTEIN EXPRESSION;

ANIMALS; BONE MARROW CELLS; CARBON TETRACHLORIDE; COCULTURE TECHNIQUES; FEMALE; GREEN FLUORESCENT PROTEINS; HEPATOCYTES; LIVER DISEASES; LIVER REGENERATION; MESENCHYMAL STEM CELLS; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC;

MUS;

EID: 67549113627     PISSN: 10656995     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cellbi.2009.04.023     Document Type: Article

References (16)

1. Cao B.Q., Lin J.Z., Zhong Y.S., Huang S.B., Lin N., Tang Z.F., et al. Contribution of mononuclear bone marrow cells to carbon tetrachloride-induced liver fibrosis in rats. World J Gastroenterol 13 12 (2007) 1854-1856 1851-4; discussion
2. Chen Y., Dong X.J., Zhang G.R., Shao J.Z., and Xiang L.X. Transdifferentiation of mouse BM cells into hepatocyte-like cells. Cytotherapy 8 4 (2006) 381-389
3. Chen Y., Dong X.J., Zhang G.R., Shao J.Z., and Xiang L.X. In vitro differentiation of mouse bone marrow stromal stem cells into hepatocytes induced by conditioned culture medium of hepatocytes. J Cell Biochem 102 1 (2007) 52-63
4. Hristov M., Keymel S., and Weber C. [The therapeutic effect of autologous bone marrow cells in ischemic heart disease]. Med Klin (Munich) 101 suppl. 1 (2006) 186-9
5. Jung Y.J., Ryu K.H., Cho S.J., Woo S.Y., Seoh J.Y., Chun C.H., et al. Syngenic bone marrow cells restore hepatic function in carbon tetrachloride-induced mouse liver injury. Stem Cells Dev 15 5 (2006) 687-695
6. Lange C., Bruns H., Kluth D., Zander A.R., and Fiegel H.C. Hepatocytic differentiation of mesenchymal stem cells in cocultures with fetal liver cells. World J Gastroenterol 12 15 (2006) 2394-2397
7. Morio L.A., Chiu H., Sprowles K.A., Zhou P., Heck D.E., Gordon M.K., et al. Distinct roles of tumor necrosis factor-alpha and nitric oxide in acute liver injury induced by carbon tetrachloride in mice. Toxicol Appl Pharmacol 172 1 (2001) 44-51
8. Okumoto K., Saito T., Hattori E., Ito J.I., Adachi T., Takeda T., et al. Differentiation of bone marrow cells into cells that express liver-specific genes in vitro: implication of the Notch signals in differentiation. Biochem Biophys Res Commun 304 4 (2003) 691-695
9. Okumoto K., Saito T., Haga H., Hattori E., Ishii R., Karasawa T., et al. Characteristics of rat bone marrow cells differentiated into a liver cell lineage and dynamics of the transplanted cells in the injured liver. J Gastroenterol 41 1 (2006) 62-69
10. Ong S.Y., Dai H., and Leong K.W. Hepatic differentiation potential of commercially available human mesenchymal stem cells. Tissue Eng 12 12 (2006) 3477-3485
11. Russo F.P., Alison M.R., Bigger B.W., Amofah E., Florou A., Amin F., et al. The bone marrow functionally contributes to liver fibrosis. Gastroenterology 130 6 (2006) 1807-1821
12. Sato Y., Matsui K., Ajiki T., Igarashi Y., Takahashi M., Murakami T., et al. Can a bone marrow cell contribute to organ regeneration? In vivo analysis using transgenic rats with reporter genes. Transplant Proc 37 1 (2005) 273-275
13. Strauer B.E., Brehm M., Zeus T., Kostering M., Hernandez A., Sorg R.V., et al. Repair of infarcted myocardium by autologous intracoronary mononuclear bone marrow cell transplantation in humans. Circulation 106 15 (2002) 1913-1918
14. Talens-Visconti R., Bonora A., Jover R., Mirabet V., Carbonell F., Castell J.V., et al. Hepatogenic differentiation of human mesenchymal stem cells from adipose tissue in comparison with bone marrow mesenchymal stem cells. World J Gastroenterol 12 36 (2006) 5834-5845
15. Terai S., Sakaida I., Nishina H., and Okita K. Lesson from the GFP/CCl4 model-translational research project: the development of cell therapy using autologous bone marrow cells in patients with liver cirrhosis. J Hepatobiliary Pancreat Surg 12 3 (2005) 203-207
16. Terai S., Ishikawa T., Omori K., Aoyama K., Marumoto Y., Urata Y., et al. Improved liver function in patients with liver cirrhosis after autologous bone marrow cell infusion therapy. Stem Cells 24 10 (2006) 2292-2298