Transdifferentiation of mouse BM cells into hepatocyte-like cells

Cytotherapy

Volumn 8, Issue 4, 2006, Pages 381-389

  Chen, Y ^a   Dong, X J ^b   Zhang, G R ^b   Shao, J Z ^a   Xiang, L X ^a  

^a ZHEJIANG UNIVERSITY   (China)

^b SHAOXING PEOPLE S HOSPITAL   (China)

Author keywords

BM cell; Fibroblast growth factor 4; Hepatocyte growth factor; Hepatocytes; Liver injured sera; Oncostatin M; Transdifferentiation

Indexed keywords

ALPHA FETOPROTEIN; CREATINE KINASE; FIBROBLAST GROWTH FACTOR 4; GLYCOGEN; HEPATOCYTE NUCLEAR FACTOR 3BETA; LIVER PROTEIN; MESSENGER RNA; ONCOSTATIN M; SCATTER FACTOR; TRANSACTIVATOR PROTEIN; UREA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BONE MARROW CELL; CELL CULTURE; CELL DIFFERENTIATION; CELL FUNCTION; CELL ISOLATION; CELL STRUCTURE; CONTROLLED STUDY; CULTURE MEDIUM; FEMUR; IMMUNOFLUORESCENCE; IN VITRO STUDY; LIVER CELL; LIVER FAILURE; LIVER INJURY; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SERUM; TIBIA;

ANIMALS; BONE MARROW CELLS; CELL DIFFERENTIATION; CELL LINEAGE; CELL SHAPE; CELLS, CULTURED; GENE EXPRESSION PROFILING; GLYCOGEN; HEPATOCYTES; LIVER; MALE; MICE; UREA;

EID: 33747719852     PISSN: 14653249     EISSN: 14772566     Source Type: Journal    
DOI: 10.1080/14653240600735800     Document Type: Article

References (21)

1. Min, AD and Theise, ND. (2004) Prospects for cell-based therapies for liver disease Panminerva Med, 46, pp. 43-8.
2. Horwitz, EM. (2003) Stem cell plasticity: The growing potential of cellular therapy Arch Med Res, 34, pp. 600-6.
3. Wagers, AJ and Weissman, IL. (2004) Plasticity of adult stem cells Cell, 116, pp. 639-48.
4. Grove, JE and Bruscia, E and Krause, DS. (2004) Plasticity of bone marrow-derived stem cells Stem Cells, 22, pp. 487-500.
5. Mezey, E and Chandross, KJ and Harta, G and (2000) Turning blood into brain: Cells bearing neuronal antigens generated in vivo from bone marrow Science, 290, pp. 1779-82.
6. Orlic, D and Kajstura, J and Chimenti, S and (2001) Bone marrow cells regenerate infarcted myocardium Nature, 410, pp. 701-5.
7. Petersen, BE and Bowen, WC and Patrene, KD and (1999) Bone marrow as a potential source of hepatic oval cells Science, 284, pp. 1168-70.
8. Triaca, V and Aloe, L. (2005) Neuronal markers expression of NGF-primed bone marrow cells (BMCs) transplanted in the brain of 6-hydroxydopamine and ibotenic acid lesioned littermate mice Neurosci Lett, 384, pp. 82-6.
9. Theise, ND and Badve, S and Saxena, R and (2000) Derivation of hepatocytes from bone marrow cells in mice after radiation-induced myeloablation Hepatology, 31, pp. 235-40.
10. Alison, MR and Poulsom, R and Jeffery, R and (2000) Hepatocytes from non-hepatic adult stem cells Nature, 406, pp. 257.
11. Okumoto, K and Saito, T and Hattori, E and (2005) Differentiation of rat bone marrow cells cultured on artificial basement membrane containing extracellular matrix into a liver cell lineage J Hepatol, 43, pp. 110-6.
12. Wang, PP and Wang, JH and Yan, ZP and (2004) Expression of hepatocyte-like phenotypes in bone marrow stromal cells after HGF induction Biochem Biophys Res Commun, 320, pp. 712-6.
13. Lee, KD and Kuo, TK and Whang-Peng, J and (2004) In vitro hepatic differentiation of human mesenchymal stem cells Hepatology, 40, pp. 1275-84.
14. Seo, MJ and Suh, SY and Bae, YC and (2005) Differentiation of human adipose stromal cells into hepatic lineage in vitro and in vivo Biochem Biophys Res Commun, 328, pp. 258-64.
15. Jang, YY and Collector, MI and Baylin, SB and (2004) Hematopoietic stem cells convert into liver cells within days without fusion Nat Cell Biol, 6, pp. 532-9.
16. Rappolee, DA and Basilico, C and Patel, Y and (1994) Expression and function of FGF-4 in peri-implantation development in mouse embryos Development, 120, pp. 2259-69.
17. Teratani, T and Yamamoto, H and Aoyagi, K and (2005) Direct hepatic fate specification from mouse embryonic stem cells Hepatology, 41, pp. 836-46.
18. Chinzei, R and Tanaka, Y and Shimizu-Saito, K and (2002) Embryoid-body cells derived from a mouse embryonic stem cell line show differentiation into functional hepatocytes Hepatology, 36, pp. 22-9.
19. Heng, BC and Yu, H and Yin, Y and (2005) Factors influencing stem cell differentiation into the hepatic lineage in vitro J Gastroenterol Hepatol, 20, pp. 975-87.
20. Hong, SH and Gang, EJ and Jeong, JA and (2005) In vitro differentiation of human umbilical cord blood-derived mesenchymal stem cells into hepatocyte-like cells Biochem Biophys Res Commun, 330, pp. 1153-61.
21. Lange, C and Bassler, MV and Liozno, V and (2005) Hepatocytic gene expression in cultured rat mesenchymal stem cells Transplant Proc, 37, pp. 276-9.