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Volumn 46, Issue 12, 2008, Pages 822-830

Comparison of toxicity of selected mustard agents by percutaneous and subcutaneous routes

Author keywords

Mechlorethamine; Nitrogen mustard; Oxidative stress; Sulphur mustard; Toxicity

Indexed keywords

BRASSICA; BRASSICACEAE; MUS;

EID: 67549112948     PISSN: 00195189     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (17)

References (38)
  • 1
    • 0025185778 scopus 로고
    • The early history of the biological alkylating agents 1918-1968
    • Brookes P, The early history of the biological alkylating agents, 1918 - 1968. Mutat Res, 233 (1990) 3.
    • (1990) Mutat Res , vol.233 , pp. 3
    • Brookes, P.1
  • 2
    • 0346099400 scopus 로고    scopus 로고
    • Management with topical nitrogen mustard in mycosis fungoides
    • Kim Y H, Management with topical nitrogen mustard in mycosis fungoides, Dermatol Ther, 16 (2003) 288.
    • (2003) Dermatol Ther , vol.16 , pp. 288
    • Kim, Y.H.1
  • 3
    • 0029059542 scopus 로고
    • Nitrogen mustard inhibits transcription and translation in a cell free system
    • Masta A, Gray P J & Phillips D R, Nitrogen mustard inhibits transcription and translation in a cell free system. Nucleic Acids Res, 23 (1995) 3508.
    • (1995) Nucleic Acids Res , vol.23 , pp. 3508
    • Masta, A.1    Gray, P.J.2    Phillips, D.R.3
  • 4
    • 0000904604 scopus 로고
    • Studies related to the mechanism of action of cytotoxic alkylating agents: A review
    • Wheeler G P, Studies related to the mechanism of action of cytotoxic alkylating agents: a review. Cancer Res, 22 (1962) 651.
    • (1962) Cancer Res , vol.22 , pp. 651
    • Wheeler, G.P.1
  • 5
    • 0000130061 scopus 로고
    • The reaction of mustard gas with nucleic acids in vitro and in vivo
    • Brookes P & Lawley P D, The reaction of mustard gas with nucleic acids in vitro and in vivo. Biochemical J, 77 (1960) 478.
    • (1960) Biochemical J , vol.77 , pp. 478
    • Brookes, P.1    Lawley, P.D.2
  • 6
    • 0005942065 scopus 로고
    • DNA damage and mutagenesis induced by nitrogen mustards
    • Povirk L F & Shuker D E, DNA damage and mutagenesis induced by nitrogen mustards. Mutat Res, 318 (1994) 205.
    • (1994) Mutat Res , vol.318 , pp. 205
    • Povirk, L.F.1    Shuker, D.E.2
  • 7
    • 0028943798 scopus 로고
    • Alkylation of DNA by the nitrogen mustard bis (2-chloroethyl) methylamine
    • Osborne M R, Wilman D E & Lawley P D, Alkylation of DNA by the nitrogen mustard bis (2-chloroethyl) methylamine. Chem Res Toxicol, 8 (1995) 316.
    • (1995) Chem Res Toxicol , vol.8 , pp. 316
    • Osborne, M.R.1    Wilman, D.E.2    Lawley, P.D.3
  • 8
    • 0022616154 scopus 로고
    • DNA sequence selectivity of guanine-N7 alkylation by nitrogen mustards
    • Mattes W B, Hartley J A & Kohn K W, DNA sequence selectivity of guanine-N7 alkylation by nitrogen mustards. Nucleic Acids Res, 14 (1986) 2971.
    • (1986) Nucleic Acids Res , vol.14 , pp. 2971
    • Mattes, W.B.1    Hartley, J.A.2    Kohn, K.W.3
  • 9
    • 0022827320 scopus 로고    scopus 로고
    • Reactions of nitrogen mustards with DNA
    • 1986
    • Hemminki K & Kallama S, (1986). Reactions of nitrogen mustards with DNA. IARC Sci Publ, 78 (1986) 55.
    • IARC Sci Publ , vol.78 , Issue.1986 , pp. 55
    • Hemminki, K.1    Kallama, S.2
  • 10
    • 0026326721 scopus 로고
    • Thermolabile adenine adducts and A T base pair substitutions induced by nitrogen mustard analogues in an SV40- based shuttle vector
    • Wang P, Bauer G B, Bennett R A O & Powrk L F, Thermolabile adenine adducts and A T base pair substitutions induced by nitrogen mustard analogues in an SV40- based shuttle vector, Biochemistry, 30 (1991) 11515.
    • (1991) Biochemistry , vol.30 , pp. 11515
    • Wang, P.1    Bauer, G.B.2    Bennett, R.A.O.3    Powrk, L.F.4
  • 14
    • 0037710325 scopus 로고    scopus 로고
    • Prophylactic protection by N-acetyl cysteine against the pulmonary injury induced by 2-chloroethyl ethyl sulphide, a mustard analogue
    • Das S K, Mukherjee S, Smith M G & Chatterjee D, Prophylactic protection by N-acetyl cysteine against the pulmonary injury induced by 2-chloroethyl ethyl sulphide, a mustard analogue. J Biochem Mol Toxicol, 17 (2003) 177.
    • (2003) J Biochem Mol Toxicol , vol.17 , pp. 177
    • Das, S.K.1    Mukherjee, S.2    Smith, M.G.3    Chatterjee, D.4
  • 15
    • 1842559783 scopus 로고    scopus 로고
    • Protection by antioxidants aganist toxicity and apoptosis induced by the sulphur mustard analog 2- chloro ethy sulphide (CEES) in Jurkat T Cells and normal human lymphocytes
    • Han S, Espinoza L A, Liao H, Boulares A H & Samulson M E, Protection by antioxidants aganist toxicity and apoptosis induced by the sulphur mustard analog 2- chloro ethy sulphide (CEES) in Jurkat T Cells and normal human lymphocytes. Br J Pharmacol, 141 (2004) 795.
    • (2004) Br J Pharmacol , vol.141 , pp. 795
    • Han, S.1    Espinoza, L.A.2    Liao, H.3    Boulares, A.H.4    Samulson, M.E.5
  • 16
    • 33846840772 scopus 로고    scopus 로고
    • Dose and time dependent effects of sulphur mustard on antioxidant system in liver and brain of rat
    • Jafari M, Dose and time dependent effects of sulphur mustard on antioxidant system in liver and brain of rat. Toxicology, 231 (2007) 30.
    • (2007) Toxicology , vol.231 , pp. 30
    • Jafari, M.1
  • 17
    • 33846249767 scopus 로고    scopus 로고
    • Comparative toxicity studies of sulphur mustard (2,2' dichloro diethyl sulphide) and monofunctional sulphur mustard (2-chloro ethyl sulphide) administered through various routes
    • Gautam A, Vijayaraghavan R, Sharma M & Ganesan K, Comparative toxicity studies of sulphur mustard (2,2' dichloro diethyl sulphide) and monofunctional sulphur mustard (2-chloro ethyl sulphide) administered through various routes. J Med CBRN Def, 4 (2006) e1.
    • (2006) J Med CBRN Def , vol.4
    • Gautam, A.1    Vijayaraghavan, R.2    Sharma, M.3    Ganesan, K.4
  • 19
    • 0017064979 scopus 로고
    • A fluorometric method for determination of oxidised and reduced glutathione in tissues
    • Hisin P J & Hilf R, A fluorometric method for determination of oxidised and reduced glutathione in tissues. Anal Biochem, 74 (1976) 214.
    • (1976) Anal Biochem , vol.74 , pp. 214
    • Hisin, P.J.1    Hilf, R.2
  • 20
    • 0017872475 scopus 로고
    • Microsomal lipid peroxidation
    • Buege J A & Aust S D, Microsomal lipid peroxidation. Method Enzymol, 52 (1978) 303.
    • (1978) Method Enzymol , vol.52 , pp. 303
    • Buege, J.A.1    Aust, S.D.2
  • 21
    • 0032697199 scopus 로고    scopus 로고
    • Sulphur mustard induced DNA damage in mice after dermal and inhalation exposure
    • Rao P V L, Vijayaraghavan R & Bhaskar A S B, Sulphur mustard induced DNA damage in mice after dermal and inhalation exposure. Toxicology, 139 (1999) 39.
    • (1999) Toxicology , vol.139 , pp. 39
    • Rao, P.V.L.1    Vijayaraghavan, R.2    Bhaskar, A.S.B.3
  • 22
    • 0018830636 scopus 로고
    • Glucocorticoid induced thymocyte apoptosis is associated with endonulease activation
    • Wyllie A H, Glucocorticoid induced thymocyte apoptosis is associated with endonulease activation. Nature, 284 (1980) 555.
    • (1980) Nature , vol.284 , pp. 555
    • Wyllie, A.H.1
  • 23
    • 0026010094 scopus 로고
    • Dermal intoxication of mice with bis(2cloroethyl) sulphide and the protective effects of flavonoids
    • Vijayaraghavan R, Sugendran K, Pant S C, Hussain K & Malhotra R C, Dermal intoxication of mice with bis(2cloroethyl) sulphide and the protective effects of flavonoids. Toxicology, 69 (1991) 35.
    • (1991) Toxicology , vol.69 , pp. 35
    • Vijayaraghavan, R.1    Sugendran, K.2    Pant, S.C.3    Hussain, K.4    Malhotra, R.C.5
  • 25
    • 0027420576 scopus 로고
    • Biochemical manipulation of intracellular glutathione levels influences cytotoxicity to isolated human lymphocytes by sulfur mustard
    • Gross C L, Innace J K, Hovatter R C, Meier H L & Smith W J, Biochemical manipulation of intracellular glutathione levels influences cytotoxicity to isolated human lymphocytes by sulfur mustard. Cell Biol Toxicol, 9 (1993) 259.
    • (1993) Cell Biol Toxicol , vol.9 , pp. 259
    • Gross, C.L.1    Innace, J.K.2    Hovatter, R.C.3    Meier, H.L.4    Smith, W.J.5
  • 26
    • 0035857792 scopus 로고    scopus 로고
    • Protective effect of various antioxidants on the toxicity of sulphur mustard administered to mice by inhalation or percutaneous route
    • Kumar O, Sugendran K & Vijayaraghavan R, Protective effect of various antioxidants on the toxicity of sulphur mustard administered to mice by inhalation or percutaneous route. Chem Biol Interact, 134 (2001) 1.
    • (2001) Chem Biol Interact , vol.134 , pp. 1
    • Kumar, O.1    Sugendran, K.2    Vijayaraghavan, R.3
  • 28
    • 0029049590 scopus 로고
    • Assessment of sulfur mustard interaction with basement membrane components
    • Zhang Z, Peters B P & Monteiro-Riviere N A, Assessment of sulfur mustard interaction with basement membrane components. Cell Biol Toxicol, 11 (1995) 89.
    • (1995) Cell Biol Toxicol , vol.11 , pp. 89
    • Zhang, Z.1    Peters, B.P.2    Monteiro-Riviere, N.A.3
  • 29
    • 0030579099 scopus 로고    scopus 로고
    • Effects of calmodulin antagonists and anaesthetics on the skin lesions induced by 2-chloroethyl sulfide
    • Kim Y B, Hur G H, Choi D S, Shin S, Han B G, Lee Y S & Sok D E, Effects of calmodulin antagonists and anaesthetics on the skin lesions induced by 2-chloroethyl sulfide. Eur J Pharmacol, 313 (1996) 107.
    • (1996) Eur J Pharmacol , vol.313 , pp. 107
    • Kim, Y.B.1    Hur, G.H.2    Choi, D.S.3    Shin, S.4    Han, B.G.5    Lee, Y.S.6    Sok, D.E.7
  • 30
    • 0345183619 scopus 로고    scopus 로고
    • Factors affecting percutaneous absorption
    • V A Drill, P Lazar, edited by (Academic Press, New York)
    • Malkinson F D & Gehlmann L, Factors affecting percutaneous absorption. in: V A Drill, P Lazar, Cutaneous coxicity, edited by (Academic Press, New York), (1997) pp. 63.
    • (1997) Cutaneous Coxicity , pp. 63
    • Malkinson, F.D.1    Gehlmann, L.2
  • 31
    • 0003112577 scopus 로고
    • Histochemical localisation of three basement membrane epitopes with sulphur mustard induced toxicity in porcine skin
    • Monteiro-Riviere N A & Inman A O, Histochemical localisation of three basement membrane epitopes with sulphur mustard induced toxicity in porcine skin. Toxicologist, 13 (1993) 58.
    • (1993) Toxicologist , vol.13 , pp. 58
    • Monteiro-Riviere, N.A.1    Inman, A.O.2
  • 32
    • 0029063209 scopus 로고
    • Evaluation of protective effects of sodium thiosulfate, cysteine, niacinamide and indomethacin on sulfur mustard-treated isolated perfused porcine skin
    • Zhang Z, Riviere J E & Monteiro-Riviere N A, Evaluation of protective effects of sodium thiosulfate, cysteine, niacinamide and indomethacin on sulfur mustard-treated isolated perfused porcine skin. Chem Biol Interact, 96 (1995) 249.
    • (1995) Chem Biol Interact , vol.96 , pp. 249
    • Zhang, Z.1    Riviere, J.E.2    Monteiro-Riviere, N.A.3
  • 33
    • 0027225506 scopus 로고
    • Biological fate of sulphur mustard (1,1V-thiobis(2-chloroethane)): Uptake, distribution and retention of 35S in skin and in blood after cutaneous application of 35S mustard in rat and comparison with human blood in vitro
    • Hambrook J L, Howells D J & Schock C, Biological fate of sulphur mustard (1,1V-thiobis(2-chloroethane)): uptake, distribution and retention of 35S in skin and in blood after cutaneous application of 35S mustard in rat and comparison with human blood in vitro. Xenobiotica, 23 (1993) 537.
    • (1993) Xenobiotica , vol.23 , pp. 537
    • Hambrook, J.L.1    Howells, D.J.2    Schock, C.3
  • 34
    • 0034277945 scopus 로고    scopus 로고
    • Human skin absorption of Bis-2-(chloroethyl)sulphide (sulphur mustard) in vitro
    • Chilcott R P, Jenner J, Carrick W, Hotchkiss S A & Rice P, Human skin absorption of Bis-2-(chloroethyl)sulphide (sulphur mustard) in vitro. J Appl Toxicol, 20 (2000) 349.
    • (2000) J Appl Toxicol , vol.20 , pp. 349
    • Chilcott, R.P.1    Jenner, J.2    Carrick, W.3    Hotchkiss, S.A.4    Rice, P.5
  • 36
    • 34547906433 scopus 로고    scopus 로고
    • The prophylactic effect of gossypin against percutaneously administered sulfur mustard
    • 2007
    • Gautam A & Vijayaraghavan R (2007). The prophylactic effect of gossypin against percutaneously administered sulfur mustard. Biomed Environ Sci, 20 (2007) 250.
    • (2007) Biomed Environ Sci , vol.20 , pp. 250
    • Gautam, A.1    Vijayaraghavan, R.2
  • 37
    • 0004238939 scopus 로고
    • Butterworth and Co. (Publishers) Ltd., London England
    • Ross W C J, Biological Alkylating Agents. Butterworth and Co. (Publishers) Ltd., London, England, (1962).
    • (1962) Biological Alkylating Agents
    • Ross, W.C.J.1
  • 38
    • 50549181939 scopus 로고
    • Metabolism of bisbetachloroethylsulfide (sulfur mustard gas)
    • Davison C, Rozman R S & Smith P K, Metabolism of bisbetachloroethylsulfide (sulfur mustard gas). Biochem Pharmacol, 7 (1961) 65.
    • (1961) Biochem Pharmacol , vol.7 , pp. 65
    • Davison, C.1    Rozman, R.S.2    Smith, P.K.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.