Emodin augments calcium activated chloride channel in colonic smooth muscle cells by Gi/Go protein

European Journal of Pharmacology

Volumn 615, Issue 1-3, 2009, Pages 171-176

  Xu, Long ^a   Ting Lou, ^a   Lv, Nonghua ^a   Zhu, Xuan ^a   Chen, Youxiang ^a   Yang, Jing ^b  

^a NANCHANG UNIVERSITY   (China)

^b WUHAN UNIVERSITY   (China)

Author keywords

ClCA channel; Contraction; Emodin; Gi Go protein; Patch clamp; Smooth muscle cell

Indexed keywords

CALCIUM ACTIVATED CHLORIDE CHANNEL; CHLORIDE CHANNEL; CYCLIC AMP DEPENDENT PROTEIN KINASE; EMODIN; GUANINE NUCLEOTIDE BINDING PROTEIN; INHIBITORY GUANINE NUCLEOTIDE BINDING PROTEIN; PROTEIN KINASE C; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CHLORIDE CURRENT; COLON MUCOSA; CONTROLLED STUDY; DRUG MECHANISM; FEMALE; IN VITRO STUDY; INTESTINE CELL; INTESTINE CONTRACTION; MALE; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

4,4'-DIISOTHIOCYANOSTILBENE-2,2'-DISULFONIC ACID; 8-BROMO CYCLIC ADENOSINE MONOPHOSPHATE; ADENOSINE; ANIMALS; CALCIUM; CHLORIDE CHANNELS; COLON; CYCLIC AMP-DEPENDENT PROTEIN KINASES; EMODIN; FEMALE; GASTROINTESTINAL MOTILITY; GTP-BINDING PROTEIN ALPHA SUBUNITS, GI-GO; GUINEA PIGS; MALE; MYOCYTES, SMOOTH MUSCLE; NIFLUMIC ACID; PATCH-CLAMP TECHNIQUES; PERTUSSIS TOXIN; PROTEIN KINASE C; SIGNAL TRANSDUCTION; TETRADECANOYLPHORBOL ACETATE;

EID: 67449161540     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2009.04.045     Document Type: Article

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