Structural stability of vault particles

Journal of Pharmaceutical Sciences

Volumn 98, Issue 4, 2009, Pages 1376-1386

  Esfandiary, Reza ^a   Kickhoefer, Valerie A ^b   Rome, Leonard H ^b   Joshi, Sangeeta B ^a   Middaugh, C Russell ^a  

^a UNIVERSITY OF KANSAS   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

NANOCAPSULE; RIBONUCLEOPROTEIN;

ACIDITY; ARTICLE; CIRCULAR DICHROISM; DRUG DELIVERY SYSTEM; ELECTRON MICROSCOPY; FLUORESCENCE SPECTROSCOPY; IN VITRO STUDY; LIGHT SCATTERING; NONHUMAN; PH; PROTEIN EXPRESSION; PROTEIN STRUCTURE; SPECTROSCOPY; STRUCTURE ANALYSIS; TEMPERATURE;

EID: 67449149643     PISSN: 00223549     EISSN: 15206017     Source Type: Journal    
DOI: 10.1002/jps.21508     Document Type: Article

References (22)

1. Kedersha NL, Rome LH. 1986. Isolation and characterization of a novel ribonucleoprotein particle: Large structures contain a single species of small RNA. J Cell Biol 103:699-709.
2. Suprenant KA. 2002. Vault ribonucleoprotein particles: Sarcophagi, gondolas, or safety deposit boxes? Biochemistry 41:14447-14454.
3. Kickhoefer VA, Garcia Y, Mikyas Y, Johansson E, Zhou JC, Raval-Fernandes S, Minoofar P, Zink JI, Dunn B, Stewart PL, Rome LH. 2005. Engineering of vault nanocapsules with enzymatic and fluorescent properties. Proc Natl Acad Sei USA 102:4348-4352.
4. Anderson DH, Kickhoefer VA, Sievers SA, Rome LH, Eisenberg D. 2007. Draft crystal structure of the vault shell at 9-Á resolution. PLoS Biol 5:e318.
5. Stephen AG, Raval-Fernandes S, Huynh T, Torres M, Kickhoefer VA, Rome LH. 2001. Assembly of vault-like particles in insect cells expressing only the major vault protein. J Biol Chem 276:23217-23220.
6. Van Zon A, Mossink MH, Schoester M, Scheffer GL, Seheper RJ, Sonneveld P, Wiemer EAC. 2002. Structural domains of vault proteins: A role for the coiled coil domain in vault assembly. Biochem Biophys Res Commun 291:535-541.
7. Dalton WS, Seheper RJ. 1999. Lung resistance-related protein: Determining its role in multidrug resistance. J Natl Cancer Inst 91:1604-1605.
8. Kickhoefer VA, Rajavel KS, Scheffer GL, Dalton WS, Seheper RJ, Rome LH. 1998. Vaults are upregulated in multidrug-resistant cancer cell lines. J Biol Chem 273:8971-8974.
9. Mossink MH, Van Zon A, Seheper RJ, Sonneveld P, Wiemer EAC. 2003. Vaults: A ribonucleoprotein particle involved in drug resistance? Oncogene 22:7458-7467.
10. Steiner E, Holzmann K, Elbling L, Micksche M, Berger W. 2006. Cellular functions of vaults and their involvement in multidrug resistance. Curr Drug Targets 7:923-934.
11. Kozlov G, Vavelyuk O, Minailiuc O, Banville D, Gehring K, Ekiel I. 2006. Solution structure of a two-repeat fragment of major vault protein. J MoI Biol 356:444-452.
12. Kowalski MP, Dubouix-Bourandy A, Bajmoczi M, Golan DE, Zaidi T, Coutinho-Sledge YS, Gygi MP, Gygi SP, Wiemer EAC, Pier GB. 2007. Host resistance to lung infection mediated by major vault protein in epithelial cells. Science 317:130-132.
13. Mikyas Y, Makabi M, Raval-Fernandes S, Harrington L, Kickhoefer VA, Rome LH, Stewart PL. 2004. Cryoelectron microscopy imaging of recombinant and tissue derived vaults: localization of the MVP N termini and VPARP. J MoI Biol 344:91-105.
14. Goldsmith LE, Yu M, Rome LH, Monbouquette HG. 2007. Vault nanocapsule dissociation into halves triggered at low pH. Biochemistry 46:2865-2875.
15. Poderycki MJ, Kickhoefer VA, Kaddis CS, Raval- Fernandes S, Johansson E, Zink JI, Loo JA, Rome LH. 2006. The vault exterior shell is a dynamic structure that allows incorporation of vault-associated proteins into its interior. Biochemistry 45:12184-12193.
16. Ausar SF, Foubert TR, Hudson MH, Vedvick TS, Middaugh C. 2006. Conformational stability and disassembly of Norwalk virus-like particles: Effect of pH and temperature. J Biol Chem 281:19478-19488.
17. Kueltzo LA, Ersoy B, Ralston JP, Middaugh C. 2003. Derivative absorbance spectroscopy and protein phase diagrams as tools for comprehensive protein characterization: A bGCSF case study. J Pharm Sei 92:1805-1820.
18. Fan H, Li H, Zhang M, Middaugh CR. 2007. Effects of solutes on empirical phase diagrams of human fibroblast growth factor 1. J Pharm Sei 96:1490-1503.
19. Kickhoefer VA, Rome LH. 1994. The sequence of a eDNA encoding the major vault protein from Rattus Norvegicus. Gene 151:257-260.
20. Matulis D, Baumann CG, Bloomfield VA, Lovrien RE. 1999. l-Anilino-8-naphthalene sulfonate as a protein conformational tightening agent. Biopolymers 49:451-458.
21. Matulis D, Lovrien R. 1998. l-Anilmo-8-naphthalene sulfonate anion-protein binding depends primarily on ion pair formation. Biophys J 74:422-429.
22. Kuwajima K. 1989. The molten globule state as a clue for understanding the folding and cooperativity of globular-protein structure. Proteins 6:87-103.