Derivative absorbance spectroscopy and protein phase diagrams as tools for comprehensive protein characterization: A bGCSF case study

Journal of Pharmaceutical Sciences

Volumn 92, Issue 9, 2003, Pages 1805-1820

  Kueltzo, Lisa A ^a,b   Ersoy, Baran ^a   Ralston, John P ^a   Middaugh, C Russell ^a  

^a UNIVERSITY OF KANSAS   (United States)

^b UNIVERSITY OF COLORADO   (United States)

Author keywords

Absorption spectroscopy; Biophysical models; Calorimetry (DSC); Circular; Dichroism; Fluorescence spectroscopy; Infrared spectroscopy; Protein aggregation; Protein formulation; Protein structure; UV Vis spectroscopy

Indexed keywords

RECOMBINANT GRANULOCYTE COLONY STIMULATING FACTOR;

ABSORPTION SPECTROSCOPY; ARTICLE; BIOPHYSICS; CATTLE; DERIVATIVE ABSORBANCE SPECTROSCOPY; DIAGNOSTIC APPROACH ROUTE; DRUG FORMULATION; MACROMOLECULE; MATHEMATICAL ANALYSIS; NONHUMAN; PH MEASUREMENT; PHYSICAL CHEMISTRY; PROTEIN ANALYSIS; PROTEIN PHASE DIAGRAM; STRUCTURE ANALYSIS; ULTRAVIOLET RADIATION;

EID: 0041336626     PISSN: 00223549     EISSN: None     Source Type: Journal    
DOI: 10.1002/jps.10439     Document Type: Article

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