Human cytomegalovirus and Epstein-Barr virus inhibit oral bacteria-induced macrophage activation and phagocytosis

Oral Microbiology and Immunology

Volumn 24, Issue 3, 2009, Pages 243-248

  Lin, Y L ^a   Li, M ^a  

^a UNIVERSITY OF KENTUCKY COLLEGE OF DENTISTRY   (United States)

Author keywords

Cytomegalovirus; Epstein Barr virus; Macrophages; Phagocytosis

Indexed keywords

FLUORESCEIN ISOTHIOCYANATE; TOLL LIKE RECEPTOR 9; TUMOR NECROSIS FACTOR ALPHA;

ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOMEGALOVIRUS; DOWN REGULATION; EPSTEIN BARR VIRUS; HUMAN; HUMAN CELL; MACROPHAGE ACTIVATION; MOUTH FLORA; NONHUMAN; PERIODONTAL DISEASE; PHAGOCYTOSIS; POLYMERASE CHAIN REACTION; PROTEIN EXPRESSION;

ACTINOBACILLUS ACTINOMYCETEMCOMITANS; CELL LINE; CELLS, CULTURED; CYTOMEGALOVIRUS; DOWN-REGULATION; FLUORESCEIN-5-ISOTHIOCYANATE; FLUORESCENT DYES; FUSOBACTERIUM NUCLEATUM; GRAM-NEGATIVE BACTERIA; HERPESVIRUS 4, HUMAN; HUMANS; MACROPHAGE ACTIVATION; MACROPHAGES; MOUTH; PHAGOCYTOSIS; POLYMERASE CHAIN REACTION; PORPHYROMONAS GINGIVALIS; STREPTOCOCCUS GORDONII; TOLL-LIKE RECEPTOR 9; TUMOR NECROSIS FACTOR-ALPHA;

EID: 67449149015     PISSN: 09020055     EISSN: 1399302X     Source Type: Journal    
DOI: 10.1111/j.1399-302X.2009.00504.x     Document Type: Article

References (28)

1. Biggs BA, Hewish M, Kent S, Hayes K, Crowe SM. HIV-1 infection of human macrophages impairs phagocytosis and killing of Toxoplasma gondii. J Immunol 1995 : 154 : 6132 6139.
2. Cappuyns I, Gugerli P, Mombelli A. Viruses in periodontal disease - a review. Oral Dis 2005 : 11 : 219 229. (Pubitemid 40992540)
3. Contreras A, Slots J. Herpesviruses in human periodontal disease. J Periodontal Res 2000 : 35 : 3 16.
4. Contreras A, Umeda M, Chen C, Bakker I, Morrison JL, Slots J. Relationship between herpesviruses and adult periodontitis and periodontopathic bacteria. J Periodontol 1999 : 70 : 478 484.
5. Contreras A, Zadeh HH, Nowzari H, Slots J. Herpesvirus infection of inflammatory cells in human periodontitis. Oral Microbiol Immunol 1999 : 14 : 206 212. (Pubitemid 29351035)
6. Crowe SM, Vardaxis NJ, Kent SJ et al. HIV infection of monocyte-derived macrophages in vitro reduces phagocytosis of Candida albicans. J Leukoc Biol 1994 : 56 : 318 327. (Pubitemid 24295800)
7. Ding F, Feng XH, Meng HX et al. Relationship between herpesviruses and periodontal pathogenic bacteria in subgingival plaque. Beijing Da Xue Xue Bao 2008 : 40 : 318 322.
8. Doyle SE, O'Connell RM, Miranda GA et al. Toll-like receptors induce a phagocytic gene program through p38. J Exp Med 2004 : 199 : 81 90. (Pubitemid 38076480)
9. Franke-Ullmann G, Pfortner C, Walter P et al. Alteration of pulmonary macrophage function by respiratory syncytial virus infection in vitro. J Immunol 1995 : 154 : 268 280.
10. Gafa V, Manches O, Pastor A et al. Human cytomegalovirus downregulates complement receptors (CR3, CR4) and decreases phagocytosis by macrophages. J Med Virol 2005 : 76 : 361 366. (Pubitemid 40770892)
11. Gosselin J, Menezes J, D'Addario M et al. Inhibition of tumor necrosis factor-alpha transcription by Epstein-Barr virus. Eur J Immunol 1991 : 21 : 203 208.
12. Gredmark S, Tilburgs T, Soderberg-Naucler C. Human cytomegalovirus inhibits cytokine-induced macrophage differentiation. J Virol 2004 : 78 : 10378 10389. (Pubitemid 39258363)
13. Jenkins C, Garcia W, Godwin MJ et al. Immunomodulatory properties of a viral homolog of human interleukin-10 expressed by human cytomegalovirus during the latent phase of infection. J Virol 2008 : 82 : 3736 3750.
14. Kondo K. Persistent/latent infection of human beta-herpesvirus. Nippon Rinsho 1998 : 56 : 83 89.
15. Konstantinidis A, Sakellari D, Papa A, Antoniadis A. Real-time polymerase chain reaction quantification of Epstein-Barr virus in chronic periodontitis patients. J Periodontal Res 2005 : 40 : 294 298. (Pubitemid 40977303)
16. Kubar A, Saygun I, Ozdemir A, Yapar M, Slots J. Real-time polymerase chain reaction quantification of human cytomegalovirus and Epstein-Barr virus in periodontal pockets and the adjacent gingiva of periodontitis lesions. J Periodontal Res 2005 : 40 : 97 104. (Pubitemid 40417307)
17. Lin YL, Chang PC, Wang Y, Li M. Identification of novel viral interleukin-10 isoforms of human cytomegalovirus AD169. Virus Res 2008 : 131 : 213 223.
18. Michalowicz BS, Ronderos M, Camara-Silva R, Contreras A, Slots J. Human herpesviruses and Porphyromonas gingivalis are associated with juvenile periodontitis. J Periodontol 2000 : 71 : 981 988.
19. Savard M, Belanger C, Tardif M, Gourde P, Flamand L, Gosselin J. Infection of primary human monocytes by Epstein-Barr virus. J Virol 2000 : 74 : 2612 2619. (Pubitemid 30117570)
20. Savard M, Belanger C, Tremblay MJ et al. EBV suppresses prostaglandin E2 biosynthesis in human monocytes. J Immunol 2000 : 164 : 6467 6473. (Pubitemid 30408830)
21. Slots J. Update on human cytomegalovirus in destructive periodontal disease. Oral Microbiol Immunol 2004 : 19 : 217 223. (Pubitemid 38931703)
22. Slots J, Saygun I, Sabeti M, Kubar A. Epstein-Barr virus in oral diseases. J Periodontal Res 2006 : 41 : 235 244.
23. Sunde PT, Olsen I, Enersen M, Beiske K, Grinde B. Human cytomegalovirus and Epstein-Barr virus in apical and marginal periodontitis: a role in pathology? J Med Virol 2008 : 80 : 1007 1011.
24. Sunde PT, Olsen I, Enersen M, Grinde B. Patient with severe periodontitis and subgingival Epstein-Barr virus treated with antiviral therapy. J Clin Virol 2008 : 42 : 176 178.
25. Tardif M, Savard M, Flamand L, Gosselin J. Impaired protein kinase C activation/translocation in Epstein-Barr virus-infected monocytes. J Biol Chem 2002 : 277 : 24148 24154.
26. Teughels W, Sliepen I, Quirynen M et al. Human cytomegalovirus enhances A. actinomycetemcomitans adherence to cells. J Dent Res 2007 : 86 : 175 180.
27. Tugizov S, Herrera R, Veluppillai P, Greenspan J, Greenspan D, Palefsky JM. Epstein-Barr virus (EBV)-infected monocytes facilitate dissemination of EBV within the oral mucosal epithelium. J Virol 2007 : 81 : 5484 5496. (Pubitemid 46846989)
28. Zedtwitz-Liebenstein K, Jaksch P, Wulkersdorfer B et al. Usefulness of interleukin-10 detection in lung transplant patients with human cytomegalovirus infection with respect to virus persistence. Transplantation 2007 : 84 : 268 271. (Pubitemid 47205763)