Horizontal head impulse test detects gentamicin vestibulotoxicity

Neurology

Volumn 72, Issue 16, 2009, Pages 1417-1424

  Weber, K P ^a   Aw, S T ^a,b   Todd, M J ^a   McGarvie, L A ^a   Curthoys, I S ^c   Halmagyi, G M ^a  

^a ROYAL PRINCE ALFRED HOSPITAL   (Australia)

^b Faculty of Medicine   (Australia)

^c UNIVERSITY OF SYDNEY   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

GENTAMICIN; PROTEIN SYNTHESIS INHIBITOR;

ADULT; AGED; ANTIBIOTIC THERAPY; ARTICLE; BILATERAL VESTIBULAR LOSS; CALORIC VESTIBULAR TEST; CLINICAL ARTICLE; CONTROLLED STUDY; DIAGNOSTIC VALUE; EARLY DIAGNOSIS; HAIR CELL; HORIZONTAL HEAD IMPULSE TEST; HUMAN; INTERMETHOD COMPARISON; POINT OF CARE TESTING; PRIORITY JOURNAL; ROTATIONAL TESTING; SACCADIC EYE MOVEMENT; TOXICITY TESTING; VESTIBULAR DISORDER; VESTIBULOOCULAR REFLEX; CHEMICALLY INDUCED DISORDER; DRUG EFFECT; EXTRAOCULAR MUSCLE; EYE MOVEMENT; EYE MOVEMENT DISORDER; FEMALE; HEAD MOVEMENT; HOSPITAL INFORMATION SYSTEM; MALE; METHODOLOGY; MIDDLE AGED; NERVE TRACT; PATHOPHYSIOLOGY; PHYSIOLOGY; PREDICTION AND FORECASTING; SEMICIRCULAR CANAL; VESTIBULAR TEST; VESTIBULE;

ADULT; AGED; EYE MOVEMENTS; FEMALE; GENTAMICINS; HEAD MOVEMENTS; HUMANS; MALE; MIDDLE AGED; NEURAL PATHWAYS; OCULAR MOTILITY DISORDERS; OCULOMOTOR MUSCLES; POINT-OF-CARE SYSTEMS; PREDICTIVE VALUE OF TESTS; PROTEIN SYNTHESIS INHIBITORS; REFLEX, VESTIBULO-OCULAR; SACCADES; SEMICIRCULAR CANALS; VESTIBULAR DISEASES; VESTIBULAR FUNCTION TESTS; VESTIBULE, LABYRINTH;

EID: 67449113714     PISSN: 00283878     EISSN: 1526632X     Source Type: Journal    
DOI: 10.1212/WNL.0b013e3181a18652     Document Type: Article

References (39)

1. Forge A, Schacht J. Aminoglycoside antibiotics. Audiol Neurootol 2000;5:3-22.
2. Black FO, Pesznecker S, Stallings V. Permanent gentami-cin vestibulotoxicity. Otol Neurotol 2004;25:559-569.
3. Ishiyama G, Ishiyama A, Kerber K, Baloh RW. Gentami-cin ototoxicity: clinical features and the effect on the human vestibulo-ocular reflex. Acta Otolaryngol 2006; 126: 1057-1061.
4. Leigh RJ, Thurtell M. Vestibular areflexia: under the radar. Ann Neurol 2007;61:499-500.
5. Dandy WE. The surgical treatment of Meniere's disease. Surg Gynecol Obstet 1941;72:421-425.
6. J.C. Living without a balancing mechanism. N Engl J Med 1952;246:458-460.
7. Ariano RE, Zelenksky SA, Kassum DA. Aminoglycosideinduced vestibular injury: maintaining a sense of balance. Ann Pharmacother 2008;42:1282-1289.
8. Halmagyi GM, Curthoys IS. A clinical sign of canal paresis. Arch Neurol 1988;45:737-739.
9. Weber KP, Aw ST, Todd MJ, McGarvie LA, Curthoys IS, Halmagyi GM. Head impulse test in unilateral vestibular loss: vestibulo-ocular reflex and catch-up saccades. Neurology 2008;70:454-463.
10. Halmagyi GM, Yavor RA, McGarvie LA. Testing the vestlbulo-ocular reflex. In: Alford BR, Jerger J, Jenkins HA, eds. Electrophysiologic Evaluation in Otolaryngology. Basel: Karger; 1997:132-154.
11. Demer JL, Honrubia V, Baloh RW. Dynamic visual acuity: a test for oscillopsia and vestibulo-ocular reflex function. Am J Otol 1994;15:340-347.
12. Halmagyi GM, Fattore CM, Curthoys IS, Wade S. Genta-micin vestibulotoxichy. Otolaryngol Head Neck Surg 1994;111:571-574.
13. Robinson DA. A method of measuring eye movement using a scleral search coil in a magnetic field. IEEE Trans Biomed Eng 1963;10:137-145.
14. Aw ST, Fetter M, Cremer PD, Karlberg M, Halmagyi GM. Individual semicircular canal function in superior and inferior vestibular neuritis. Neurology 2001;57:768-774.
15. Black RA, Halmagyi GM, Thurtell MJ, Todd MJ, Curthoys IS. The active head-impulse test in unilateral peripheral vestibulopathy. Arch Neurol 2005;62:290-293.
16. Haslwanter T. Mathematics of three-dimensional eye rotations. Vision Res 1995;35:1727-1739.
17. Collewijn H, Smeets JB. Early components of the human vestibulo-ocular response to head rotation: latency and gain. J Neurophysiol 2000;84:376-389.
18. Lehnen N, Aw ST, Todd MJ, Halmagyi GM. Head impulse test reveals residual semicircular canal function after vestibular neurectomy. Neurology 2004;62:2294-2296.
19. Weber KP, Aw ST, Todd MJ, et al. Inter-ocular differences of the horizontal vestibulo-ocular reflex during impulsive testing. Prog Brain Res 2008;171:195-198.
20. Cleveland WS. Robust locally weighted regression and smoothing scatterplots. J Am Statist Assoc 1979;74:829-836.
21. D'Errico J. Model 2-D surfaces from scattered data: gridfitm [MATLAB computer program]. Version 2.0. In: MAT-LAB central file exchange. Available at: www.mathworks.com/matlabcentral/fileexchange/. 2006.
22. Palla A, Straumann D. Recovery of the high-acceleration vestibulo-ocular reflex after vestibular neuritis. J Assoc Res Otolaryngol 2004;5:427-435.
23. Myers JL, Well AD. Research Design and Statistical Analysis, 2nd ed. Mahwah, NJ: Lawrence Erlbaum Associates; 2003.
24. Jorns-Haderli M, Straumann D, Palla A. Accuracy of the bedside head impulse test in detecting vestibular hypofunction. J Neurol Neurosurg Psychiatry 2007;78:1113-1118.
25. Rinne T, Bronstein AM, Rudge P, Gresty MA, Luxon LM. Bilateral loss of vestibular function. Acta Otolaryngol Suppl 1995;520(pt 2):247-250.
26. Vibert D, Liard P, Hausler R. Bilateral idiopathic loss of peripheral vestibular function with normal hearing. Acta Otolaryngol 1995;115:611-615.
27. Zingler VC, Cnyrim C, Jahn K, et al. Causative factors and epidemiology of bilateral vestibulopathy in 255 patients. Ann Neurol 2007;61:524-532.
28. Carey JP, Minor LB, Peng GC, la Santina CC, Cremer PD, Haslwanter T. Changes in the three-dimensional angular vestibulo-ocular reflex following intratympanic gen-tamicin for Meniere's disease. J Assoc Res Otolaryngol 2002;3:430-443.
29. Taura A, Kojima K, Ito J, Ohmori H. Recovery of hair cell function after damage induced by gentamicin in organ culture of rat vestibular maculae. Brain Res 2006; 1098:33-48.
30. Ewald EJ. Physiologische Untersuchungen über das En-dorgan des Nervus Octavus. Wiesbaden: Bergmann; 1892.
31. Mangiardi DA, Laughlin-Williamson K, May KE, Mes-sana EP, Mountain DC, Cotanche DA. Progression of hair cell ejection and molecular markers of apoptosis in the avian cochlea following gentamicin treatment. J Comp Neurol 2004;475:1-18.
32. Dobie RA, Black FO, Pezsnecker SC, Stallings VL. Hearing loss in patients with vestibulotoxic reactions to gentamicin therapy. Arch Otolaryngol Head Neck Surg 2006; 132:253-257.
33. Rey-Martinez J, Rama-Lopez J, Soledad BM, Perez N, Artieda J. A report of two cases of unilateral vestibulopa-thie after systemic ototoxic treatment. Rev Laryngol Otol Rhinol (Bord) 2005;126:159-163.
34. Waterston JA, Halmagyi GM. Unilateral vestibulotoxicity due to systemic gentamicin therapy. Acta Otolaryngol 1998;118:474-478.
35. Baloh RW, Honrubia V, Yee RD, Hess K. Changes in the human vestibulo-ocular reflex after loss of peripheral sensitivity. Ann Neurol 1984;16:222-228.
36. Furman JM, Kamerer DB. Rotational responses in patients with bilateral caloric reduction. Acta Otolaryngol 1989; 108:355-361.
37. Myers SF. Patterns of low-frequency rotational responses in bilateral caloric weakness patients. J Vestib Res 1992;2: 123-131.
38. Ludvigh E. Amount of eye movement objectively perceptible to the unaided eye. Am J Ophthalmol 1949;32:649-650.
39. Weber KP, MacDougall HG, Halmagyi GM, Curthoys IS. Impulsive testing of semicircular canal function using video-oculography. In: Basic and Clinical Aspects of Vertigo and Dizziness, vol 1163. Ann NY Acad Sci (in press 2009).