Can n-acetylcysteine preserve peritoneal function and morphology in encapsulating peritoneal sclerosis?

Peritoneal Dialysis International

Volumn 29, Issue SUPPL. 2, 2009, Pages

  Bozkurt, Devrim ^a   Hur, Ender ^a   Ulkuden, Burcu ^a   Sezak, Murat ^a   Nar, Hasim ^a   Purclutepe, Ozlem ^a   Sen, Sait ^a   Duman, Soner ^a  

^a EGE UNIVERSITY   (Turkey)

Author keywords

Encapsulating peritoneal sclerosis; Membrane protection; NAC

Indexed keywords

ACETYLCYSTEINE; ALCOHOL; CHLORHEXIDINE GLUCONATE; SODIUM CHLORIDE; UREA; SCAVENGER;

ANIMAL EXPERIMENT; ANIMAL MODEL; CONFERENCE PAPER; CONTROLLED STUDY; DIALYSATE; DRUG EFFICACY; DRUG MECHANISM; DRUG RESPONSE; ENCAPSULATING PERITONEAL SCLEROSIS; FEMALE; LEUKOCYTE COUNT; NONHUMAN; PERITONEAL DIALYSIS; PERITONEAL DISEASE; PERITONEAL FIBROSIS; PRIORITY JOURNAL; RAT; ULTRAFILTRATION; UREA BLOOD LEVEL; VASCULARIZATION; ANIMAL; ARTICLE; COMPARATIVE STUDY; DISEASE MODEL; DRUG EFFECT; ENDOTHELIUM CELL; INTRAPERITONEAL DRUG ADMINISTRATION; METABOLISM; OXIDATIVE STRESS; PATHOLOGY; PERITONEUM; SCLEROSIS; TREATMENT OUTCOME; WISTAR RAT;

ACETYLCYSTEINE; ANIMALS; DISEASE MODELS, ANIMAL; ENDOTHELIAL CELLS; FEMALE; FREE RADICAL SCAVENGERS; INJECTIONS, INTRAPERITONEAL; OXIDATIVE STRESS; PERITONEAL DIALYSIS; PERITONEAL DISEASES; PERITONEUM; RATS; RATS, WISTAR; SCLEROSIS; TREATMENT OUTCOME;

EID: 67449107457     PISSN: 08968608     EISSN: None     Source Type: Journal    
DOI: 10.1177/089686080902902s41     Document Type: Conference Paper

References (8)

1. Ha H, Lee HB. Effect of high glucose on peritoneal mesothelial cell biology. Perit Dial Int 2000; 20(Suppl 2): S15-18.
2. Noh H, Kim JS, Han KH, Lee GT, Song JS, Chung SH, et al. Oxidative stress during peritoneal dialysis: implications in functional and structural changes in the membrane. Kidney Int 2006; 69:2022-8.
3. Maksimchik YZ, Lapshina EA, Sudnikovich EY, Zabrodskaya SV, Zavodnik IB. Protective effects of N-acetyl-L-cysteine against acute carbon tetrachloride hepatotoxicity in rats. Cell Biochem Funct 2008; 26:11-18.
4. Pereira-Filho G, Ferreira C, Schwengber A, Marroni C, Zettler C, Marroni N. Role of N-acetylcysteine on fibrosis and oxidative stress in cirrhotic rats. Arq Gastroenterol 2008; 45:156-62.
5. Ishii Y, Sawada T, Shimizu A, Tojimbara T, Nakajima I, Fuchinoue S, et al. An experimental sclerosing encapsulating peritonitis model in mice. Nephrol Dial Transplant 2001; 16:1262-6.
6. Selgas R, Bajo A, Jiménez-Heffernan JA, Sánchez-Tomero JA, Del Peso G, Aguilera A, et al. Epithelial-to-mesenchymal transition of the mesothelial cell - its role in the response of the peritoneum to dialysis. Nephrol Dial Transplant 2006; 21(Suppl 2):ii2-7.
7. de Alvaro F, Castro MJ, Dapena F, Bajo MA, Fernandez-Reyes MJ, Romero JR, et al. Peritoneal resting is beneficial in peritoneal hyperpermeability and ultrafiltration failure. Adv Perit Dial 1993; 9:56-61.
8. Kawanishi H, Kawaguchi Y, Fukui H, Hara S, Imada A, Kubo H, et al. Encapsulating peritoneal sclerosis in Japan: a prospective, controlled, multicenter study. Am J Kidney Dis 2004; 44:729-37.