Effect of high glucose on peritoneal mesothelial cell biology

Peritoneal Dialysis International

Volumn 20, Issue SUPPL. 2, 2000, Pages

  Ha, Hunjoo ^a   Lee, Hi Bahl ^a,b  

^a Soonchunhyang University   (South Korea)

^b Yonsei University College of Medicine   (South Korea)

Author keywords

Fibronectin; High glucose; Human peritoneal mesothelial cell; MCP 1; Peritoneal fibrosis; PKC; Reactive oxygen species; TGF 1

Indexed keywords

ANTIOXIDANT; DIACYLGLYCEROL; FIBRONECTIN; GLUCOSE; MESSENGER RNA; MONOCYTE CHEMOTACTIC PROTEIN 1; PROTEIN; PROTEIN KINASE C; REACTIVE OXYGEN METABOLITE; TRANSFORMING GROWTH FACTOR BETA1;

ANIMAL CELL; ARTICLE; CELL CULTURE; CONTROLLED STUDY; CYTOLOGY; DRUG MEGADOSE; ENZYME INHIBITION; EXTRACELLULAR MATRIX; FIBROSIS; GENE EXPRESSION; GLUCOSE METABOLISM; HUMAN; HUMAN CELL; LONG TERM CARE; MESOTHELIUM CELL; NONHUMAN; PATHOGENESIS; PERITONEUM; PRIORITY JOURNAL; PROTEIN SYNTHESIS; RAT; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; TISSUE INJURY;

EID: 0034047146     PISSN: 08968608     EISSN: None     Source Type: Journal    
DOI: 10.1177/089686080002002s04     Document Type: Article

References (15)

1. The Diabetes Control and Complications Trial Research Group. The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus. N Engl J Med 1993; 329:977-86.
2. Lee HB, Ha H. Development and progression of diabetic nephropathy: Future of interventions. In: Wankowicz Z, ed. Proceedings of the 5th Diabetes and Nephrology Conference; 24 September 1999; Plock, Poland. Plock: Polish Association of Nephrology; 1999: 22-37.
3. Stylianou E, Jenner LA, Davies M, Coles GA, Williams JD. Isolation, culture and characterization of human peritoneal mesothelial cells. Kidney Int 1990; 37: 1563-70.
4. Kumano K, Shimoda M, Hyodo T, Sakai T. The role of TGF-β in growth inhibition of peritoneal mesothelial cells in high glucose dialysate. Perit Dial Int 1995; 15(Suppl 7):S93-5.
5. Kumano K, Schiller B, Hjelle JT, Moran J. Effects of osmotic solutes on fibronectin mRNA expression in rat peritoneal mesothelial cells. Blood Purif 1996; 14:165-9.
6. Kang DH, Hong YS, Lim HJ, Choi JH, Han DS, Yoon KI. High glucose solution and spent dialysate stimulate the synthesis of transforming growth factor-β1 of human peritoneal mesothelial cells: Effects of cytokine costimulation. Perit Dial Int 1999; 19:221-30.
7. Ha H, Yu MR, Park MS, Lee HB. High glucose-induced TGFβ1 and fibronectin synthesis by human peritoneal mesothelial cells: Involvement of PKC [Abstract]. Perit Dial Int 1998; 18:111.
8. Ziyadeh FN, Han DC. Involvement of transforming growth factor-β and its receptors in the pathogenesis of diabetic nephropathy. Kidney Int 1997; 52(Suppl 60):S7-11.
9. Hogaboan CM, Steinhauser ML, Chensue SW, Kunkel SL. Novel role for chemokines and fibroblasts in interstitial fibrosis. Kidney Int 1998; 54:2152-9.
10. Ha H, Yu MR, Park MS, Lee HB. High glucose-induced human peritoneal mesothelial cell synthesis of monocyte chemotactic protein-1 is mediated by protein kinase C [Abstract]. Perit Dial Int 1998; 18(Suppl 1): S30.
11. King GL, Ishii H, Koya D. Diabetic vascular dysfunctions: A model of excessive activation of protein kinase C. Kidney Int 1997; 52(Suppl 60):S77-85.
12. Kim SJ, Angel P, Lafyatis R, Hattori K, Kim KY, Sporn MB, et al. Autoinduction of transforming growth factor-β1 is mediated by the AP-1 complex. Mol Cell Biol 1990; 10:1492-7.
13. Dean DC. Expression of the fibronectin gene. Am J Respir Cell Mol Biol 1989; 1:5-10.
14. Chakaraborti S, Chakaraborti T. Oxidant-mediated activation of mitogen-activated protein kinases and nuclear transcription factors in the cardiovascular system: A brief overview. Cell Signal 1998; 10:675-83.
15. Ha H, Yu MR, Ahn YS, Lee HB. Activation of nuclear factor-κB in mesangial cells cultured under high glucose [Abstract]. J Am Soc Nephrol 1998; 9:631A.