More than 45% of A549 and H446 cells are cancer initiating cells: Evidence from cloning and tumorigenic analyses

Oncology Reports

Volumn 21, Issue 4, 2009, Pages 995-1000

  Meng, Xiangjiao ^a   Wang, Xiuwen ^a   Wang, Yawei ^a  

^a SHANDONG UNIVERSITY   (China)

Author keywords

Cancer initiating cells; CD133; Clone and tumorigenic analyses; Hoechst 33342; Lung cancer cell line

Indexed keywords

CD133 ANTIGEN; HOE 33342; BENZIMIDAZOLE DERIVATIVE; GLYCOPROTEIN; LEUKOCYTE ANTIGEN; OCTAMER TRANSCRIPTION FACTOR 4; PEPTIDE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BAGG ALBINO MOUSE; CANCER CELL CULTURE; CANCER STEM CELL; CARCINOGENESIS; CELL CLONE; CELL CLONING; CELL CYCLE PHASE; CONTROLLED STUDY; GROWTH CURVE; HUMAN; HUMAN CELL; LUNG CANCER; MOLECULAR CLONING; MOUSE; NONHUMAN; NUDE MOUSE; PRIORITY JOURNAL; TUMOR GROWTH; TUMOR XENOGRAFT; ANIMAL; CELL CYCLE; CELL PROLIFERATION; LUNG TUMOR; PATHOLOGY; TUMOR CELL LINE;

ANIMALS; ANTIGENS, CD; BENZIMIDAZOLES; CELL CYCLE; CELL LINE, TUMOR; CELL PROLIFERATION; GLYCOPROTEINS; HUMANS; LUNG NEOPLASMS; MICE; MICE, INBRED BALB C; NEOPLASTIC STEM CELLS; OCTAMER TRANSCRIPTION FACTOR-3; PEPTIDES;

EID: 67449095062     PISSN: 1021335X     EISSN: 17912431     Source Type: Journal    
DOI: 10.3892/or_00000314     Document Type: Article

References (24)

1. Singh SK, Clarke ID, Terasaki M, et al: Identification of a cancer stem cell in human brain tumors. Cancer Res 63: 5821-5828, 2003.
2. Singh SK, Hawkins C, Clarke D, et al: Identification of human brain tumor initiating cells. Nature 432: 396-401, 2004.
3. Kondo T, Setoguchi T and Taga T: Persistence of a small subpopulation of cancer stem-like cells in the C6 glioma cell line. Proc Natl Acad Sci USA 101: 781-786, 2004.
4. Al-Hajj M, Wicha MS, Benito-Hernandez A, Morrison SJ and Clarke MF: Prospective identification of tumorigenic breast cancer cells. Proc Natl Acad Sci USA 100: 3983-3988, 2003.
5. Collins AT, Berry PA, Hyde C, Stower MJ and Maitland NJ: Prospective identification of tumorigenic prostate cancer stem cells. Cancer Res 65: 10946-10951, 2005.
6. + hepatocellular carcinoma cells as cancer stem/progenitor cells. Biochem Biophys Res Commun 351: 820-824, 2006.
7. Yin S, Li J, Hu C, et al: CD133 positive hepatocellular carcinoma cells possess high capacity for tumorigenicity. Int J Cancer 120: 1444-1450, 2007.
8. Hermann PC, Huber SL, Herrler T, et al: Distinct populations of cancer stem cells determine tumor growth and metastatic activity in human pancreatic cancer. Cell Stem Cell 1: 313-323, 2007.
9. Eramo A, Lotti F, Sette G, et al: Identification and expansion of the tumorigenic lung cancer stem cell population. Cell Death Differ 15: 504-514, 2008.
10. Ho MM, Ng AV, Lams S and Hung JY: Side population in human lung cancer cell lines and tumors is enriched with stem-like cancer cells. Cancer Res 67: 4827-4833, 2007.
11. O'Brien CA, Pollett A, Gallinger S and Dick JE: A human colon cancer cell capable of initiating tumour growth in immunodeficient mice. Nature 445: 106-110, 2007.
12. Ricci-Vitiani L, Lombardi DG, Pilozzi E et al: Identification and expansion of human colon-cancer-initiating cells. Nature 445: 111-115, 2007.
13. Jodan CT: Cancer stem cell biology: from leukemia to solid tumors. Curr Opin Cell Biol 16: 708-712, 2004.
14. + cancer stem cells in glioblastoma. Mol Cancer 2;5:67, 2006.
15. Bao S, Wu Q, McLendon RE, et al: Glioma stem cells promote radioresistance by preferential activation of the DNA damage response. Nature 444: 756-760, 2006.
16. -) glioblastoma-derived cancer stem cells show differential growth characteristics and molecular profiles. Cancer Res 67: 4010-4015, 2007.
17. - metastatic colon cancer cells initiate tumors. J Clin Invest 118: 2111-2120, 2008.
18. Zheng X, Shen G, Yang X and Liu W: Most C6 cells are cancer stem cells: evidence from clonal and population analyses. Cancer Res 67: 3691-3697, 2007. Erratum in: Cancer Res 67: 10097, 2007.
19. Singh S, Dwarakanath BS and Mathew TL: DNA ligand Hoechst-33342 enhances UV induced cytotoxicity in human glioma cell lines. J Photochem Photobiol B 77: 45-54, 2004.
20. Singh S, Dwarakanath BS and Mathew TL: Role of topoisomerases in cytotoxicity induced by DNA ligand Hoechst 33342 and UV-C in a glioma cell line. Indian J Exp Biol 43: 313-323, 2005.
21. Atlasi Y, Mowla SJ, Ziaee SA and Bahrami AR: OCT-4, an embryonic stem cell marker, is highly expressed in bladder cancer. Int J Cancer 120: 1598-1602, 2007.
22. Hochedlinger K, Yamada Y, Beard C and Jaenisch R: Ectopic expression of Oct-4 blocks progenitor-cell differentiation and causes dysplasia in epithelial tissues. Cell 121: 465-477, 2005.
23. Setoguchi T, Taga T and Kondo T: Cancer stem cells persist in many cancer cell lines. Cell Cycle 3: 414-415, 2004.
24. Al-Hajj M, Becker MW, Wicha M, Weissman I and Clarke MF: Therapeutic implications of cancer stem cells. Curr Opin Genet Dev 14: 43-47, 2004.