Ionized hypocalcemia in critically ill dogs

Journal of Veterinary Internal Medicine

Volumn 23, Issue 3, 2009, Pages 509-513

  Holowaychuk, M K ^a   Hansen, B D ^a   DeFrancesco, T C ^a   Marks, S L ^a  

^a NORTH CAROLINA STATE UNIVERSITY   (United States)

Author keywords

Canine; Critical care; Intensive care medicine; Sepsis; Systemic inflammatory response syndrome; Trauma

Indexed keywords

CALCIUM;

ANIMAL; ANIMAL DISEASE; ARTICLE; BLOOD; CHEMISTRY; CRITICAL ILLNESS; DOG; DOG DISEASE; HYPOCALCEMIA; MORTALITY; PROSPECTIVE STUDY; RISK FACTOR; SEPSIS;

ANIMALS; CALCIUM; CRITICAL ILLNESS; DOG DISEASES; DOGS; HYPOCALCEMIA; PROSPECTIVE STUDIES; RISK FACTORS; SEPSIS;

ANIMALIA; CANIS FAMILIARIS;

EID: 67449084309     PISSN: 08916640     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1939-1676.2009.0280.x     Document Type: Article

References (33)

1. Zivin JR, Gooley T, Zager RA, Ryan MJ. Hypocalcemia: A pervasive abnormality in the critically ill. Am J Kidney Dis 2001; 37:689-698.
2. Burchard KW, Gann DS, Colliton J, Forster J. Ionized calcium, parathormone, and mortality in critically ill surgical patients. Ann Surg 1990;212:543-550.
3. Hauser CJ, Kamrath RO, Sparks J, Shoemaker WC. Calcium homeostasis in patients with pancreatitis. Surgery 1983;94: 830-835.
4. Vivien B, Langeron O, Morell E, et al. Early hypocalcemia in severe trauma. Crit Care Med 2005;33:1946-1952.
5. Cherry RA, Bradburn E, Carney DE, et al. Do early ionized calcium levels really matter in trauma patients? J Trauma 2006;61: 774-779.
6. Ward RT, Colton DM, Meade PC, et al. Serum levels of calcium and albumin in survivors versus nonsurvivors after critical injury. J Crit Care 2004;19:54-64.
7. Szyfelbein SK, Drop LJ, Martyn JA. Persistent ionized hypocalcemia in patients during resuscitation and recovery phases of body burns. Crit Care Med 1981;9:454-458.
8. Lind L, Carlstedt F, Rastad J, et al. Hypocalcemia and parathyroid hormone secretion in critically ill patients. Crit Care Med 2000;28:93-99.
9. Desai TK, Carlson RW, Geheb MA. Prevalence and clinical implications of hypocalcemia in acutely ill patients in a medical intensive care setting. Am J Med 1988;84:209-214.
10. Zaloga GP. Hypocalcemia in critically ill patients. Crit Care Med 1992;20:251-262.
11. Chernow B, Zaloga G, McFadden E, et al. Hypocalcemia in critically ill patients. Crit Care Med 1982;10:848-851.
12. Zaloga GP, Chernow B. The multifactorial basis for hypocalcemia during sepsis: Studies of the parathyroid hormone-vitamin D axis. Ann Int Med 1987;107:36-41.
13. Aderka D, Schwartz D, Dan M, Levo Y. Bacteremic hypocalcemia: A comparison between the calcium levels of bacteremic and nonbacteremic patients with infection. Arch Int Med 1987; 147:232-236.
14. Zaloga GP. Ionized hypocalcemia during sepsis. Crit Care Med 2000;28:266-268.
15. Rude RK, Oldham SB, Sharp CF, Singer FR. Parathyroid hormone secretion in magnesium deficiency. Clin Endocrinol Metab 1978;47:800-806.
16. Rude RK, Oldham SB, Singer FR. Functional hypoparathyroidism and parathyroid hormone end-organ resistance in human magnesium deficiency. Clin Endocrinol (Oxford) 1976;5: 209-224.
17. Anast CS, Winnacker JL, Forte LR, Burns TW. Impaired release of parathyroid hormone in magnesium deficiency. J Clin Endocrinol Metab 1976;42:707-717.
18. 3. Magnes Res 1992;5:5-14.
19. Cooper DJ, Walley KR, Dodek PM, et al. Plasma ionized calcium and blood lactate concentrations are inversely correlated in human lactic acidosis. Intensive Care Med 1992;18:286-289.
20. Lopez I, Rodriguez M, Felsenfeld AJ, et al. Direct suppressive effect of acute metabolic and respiratory alkalosis on parathyroid hormone secretion in the dog. J Bone Miner Res 2003; 18:1478-1485.
21. Sayeed MM. Alterations in calcium signaling and cellular responses in septic injury. New Horiz 1996;4:72-86.
22. 2+ regulation in the liver in endotoxic shock. Am J Physiol 1986;250:R884-R891.
23. Carlstedt F, Erickson M, Kiiski R, et al. Hypocalcemia during porcine endotoxemic shock: Effects of calcium administration. Crit Care Med 2000;28:2909-2914.
24. Whang KT, Steinwald PM, White JC, et al. Serum calcitonin precursors in sepsis and systemic inflammation. J Clin Endocrinol Metab 1998;83:3296-3301.
25. Muller B, Becker KL, Kranzlin M, et al. Disordered calcium homeostasis of sepsis: Association with calcitonin precursors. Eur J Clin Invest 2000;30:823-831.
26. Wanner GA, Keel M, Steckholzer U, et al. Relationship between procalcitonin plasma levels and severity of injury, sepsis, organ failure, and mortality in injured patients. Crit Care Med 2000; 28:950-957.
27. Muller B, Becker KL, Schachinger H, et al. Calcitonin precursors are reliable markers of sepsis in a medical intensive care unit. Crit Care Med 2000;28:977-983.
28. Hopper K, Rezende ML, Haskins SC. Assessment of the effect of dilution of blood samples with sodium heparin on blood gas, electrolyte, and lactate measurements in dogs. Am J Vet Res 2005;66:656-660.
29. Hauptman JG, Walshaw R, Olivier NB. Evaluation of the sensitivity and specificity of diagnostic criteria for sepsis in dogs. Vet Surg 1997;26:393-397.
30. Brainard BM, Campbell VL, Drobatz KJ, et al. The effects of surgery and anesthesia on blood magnesium and calcium concentrations in canine and feline patients. Vet Anaesth Analg 2007; 34:89-98.
31. Vaden SL, Levine J, Breitschwerdt EB. Retrospective casecontrol of acute renal failure in 99 dogs. J Vet Intern Med 1997; 11:58-64.
32. Hume DZ, Drobatz KJ, Hess RS. Outcome of dogs with diabetic ketoacidosis: 127 dogs (1993-2003). J Vet Intern Med 2006; 20:547-555.
33. Bhattacharya SK, Luther RW, Pate JW, et al. Soft tissue calcium and magnesium content in acute pancreatitis in the dog: Calcium accumulation, a mechanism for hypocalcemia in acute pancreatitis. J Lab Clin Med 1985;105:422-427.