Evaluation of postmortem S100B levels in the cerebrospinal fluid with regard to the cause of death in medicolegal autopsy

Legal Medicine

Volumn 11, Issue SUPPL. 1, 2009, Pages

  Li, Dong Ri ^a,b   Michiue, Tomomi ^a   Zhu, Bao Li ^a,c   Ishikawa, Takaki ^a   Quan, Li ^a   Zhao, Dong ^a   Yoshida, Chiemi ^a   Chen, Jian Hua ^a   Wang, Qi ^a   Komatsu, Ayumi ^a   Azuma, Yoko ^a   Maeda, Hitoshi ^a  

^a OSAKA CITY UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b SICHUAN UNIVERSITY   (China)

^c CHINA MEDICAL UNIVERSITY   (China)

Author keywords

Brain damage; Cerebrospinal fluid; Forensic pathophysiology; Postmortem biochemistry; S100B

Indexed keywords

PROTEIN S100B;

ADOLESCENT; ADULT; AGED; ARTICLE; ASPHYXIA; AUTOPSY; BLUNT TRAUMA; CAUSE OF DEATH; CHILD; COLD EXPOSURE; DROWNING; EVALUATION; FATALITY; FEMALE; FORENSIC PATHOLOGY; HEAD INJURY; HEART DEATH; HEAT STROKE; HUMAN; HYPERTHERMIA; HYPOTHERMIA; INFANT; INTOXICATION; MALE; PNEUMONIA; PRESCHOOL CHILD; PROTEIN CEREBROSPINAL FLUID LEVEL; SCHOOL CHILD; SURVIVAL TIME;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; BIOLOGICAL MARKERS; CHILD; CHILD, PRESCHOOL; FEMALE; FIRES; FORENSIC PATHOLOGY; HUMANS; HYPOTHERMIA; INFANT; INFANT, NEWBORN; INJURY SEVERITY SCORE; MALE; MIDDLE AGED; MYOCARDIAL INFARCTION; NERVE GROWTH FACTORS; PNEUMONIA; POSTMORTEM CHANGES; S100 PROTEINS; WOUNDS AND INJURIES; YOUNG ADULT;

EID: 67349283040     PISSN: 13446223     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.legalmed.2009.02.042     Document Type: Article

References (12)

1. Donato R. S100: a multigenic family of calcium-modulated proteins of the EF-hand type with intracellular and extracellular functional roles. Int J Biochem Cell Biol 33 (2001) 637-668
2. Isobe T., Takahashi K., and Okuyama T. S100aa (alpha alpha) protein is present in neurons of the central and peripheral nervous system. J Neurochem 43 (1984) 1494-1496
3. Raabe A., Grolms C., Sorge O., Zimmermann M., and Seifert V. Serum S-100B protein in severe head injury. Neurosurgery 45 (1999) 477-483
4. Stroick M., Fatar M., Ragoschke-Schumm A., Fassbender K., Bertsch T., and Hennerici M.G. Protein S-100B - a prognostic marker for cerebral damage. Curr Med Chem 13 (2006) 3053-3060
5. Shore P.M., Berger R.P., Varma S., Janesko K.L., Wisniewski S.R., Clark R.S., et al. Cerebrospinal fluid biomarkers versus glasgow coma scale and glasgow outcome scale in pediatric traumatic brain injury: the role of young age and inflicted injury. J Neurotrauma 24 (2007) 75-86
6. Persson L., Hårdemark H.G., Gustafsson J., Rundström G., Mendel-Hartvig I., Esscher T., et al. S-100 protein and neuron-specific enolase in cerebrospinal fluid and serum: markers of cell damage in human central nervous system. Stroke 18 (1987) 911-918
7. Berger R.P., Pierce M.C., Wisniewski S.R., Adelson P.D., Clark R.S., Ruppel R.A., et al. Neuron-specific enolase and S100B in cerebrospinal fluid after severe traumatic brain injury in infants and children. Pediatrics 109 (2002) E31
8. Li D.R., Zhu B.L., Ishikawa T., Zhao D., Michiue T., and Maeda H. Postmortem serum protein S100B levels with regard to the cause of death involving brain damage in medicolegal autopsy cases. Leg Med 8 (2006) 71-77
9. Beaudeux J.L., Léger P., Dequen L., Gandjbakhch I., Coriat P., and Foglietti M.J. Influence of hemolysis on the measurement of S-100beta protein and neuron-specific enolase plasma concentrations during coronary artery bypass grafting. Clin Chem 46 (2000) 989-990
10. Hanley J.A., and McNeil B.J. A method of comparing the areas under receiver operating characteristic curves derived from the same cases. Radiology 148 (1983) 839-843
11. Ruokonen E., Ilkka L., Niskanen M., and Takala J. Procalcitonin and neopterin as indicators of infection in critically ill patients. Acta Anaesthesiol Scand 46 (2002) 398-404
12. Li D.R., Zhu B.L., Ishikawa T., Zhao D., Michiue T., and Maeda H. Immunohistochemical distribution of S-100 protein in the cerebral cortex with regard to the cause of death in forensic autopsy. Leg Med 8 (2005) 75-85