Preparation of ergoloid mesylate submicron emulsions for enhancing nasal absorption and reducing nasal ciliotoxicity

International Journal of Pharmaceutics

Volumn 375, Issue 1-2, 2009, Pages 16-21

  Yu, Chaoqun ^a   Meng, Jia ^a   Chen, Jian ^a   Tang, Xing ^a  

^a SHENYANG PHARMACEUTICAL UNIVERSITY   (China)

Author keywords

Brain targeting; Ciliotoxicity; Ergoloid mesylate; Microdialysis; Nasal absorption; Submicron emulsions

Indexed keywords

DIHYDROERGOTOXINE MESILATE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; AREA UNDER THE CURVE; ARTICLE; CONTROLLED STUDY; CYTOTOXICITY; DRUG ABSORPTION; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; DRUG CEREBROSPINAL FLUID LEVEL; DRUG TRANSPORT; EMULSION; MALE; MICRODIALYSIS; NONHUMAN; PALATE; PRIORITY JOURNAL; RAT; STEREOCILIUM; TOAD;

ADMINISTRATION, INTRANASAL; ANIMALS; ANURA; AREA UNDER CURVE; BIOLOGICAL AVAILABILITY; BIOLOGICAL TRANSPORT; BRAIN; CILIA; DRUG DELIVERY SYSTEMS; EMULSIONS; ERGOLOID MESYLATES; MALE; MICRODIALYSIS; NASAL MUCOSA; PALATE; RATS; RATS, SPRAGUE-DAWLEY; TOXICITY TESTS;

EID: 67349280192     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2009.03.006     Document Type: Article

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