Epigenomic derangement of hepatic glucose metabolism by feeding of high fructose diet and its prevention by Rosiglitazone in rats

Digestive and Liver Disease

Volumn 41, Issue 7, 2009, Pages 500-508

  Yadav, H ^a   Jain, S ^a   Yadav, M ^b   Sinha, P R ^a   Prasad, G B K S ^b   Marotta, F ^c  

^a NATIONAL DAIRY RESEARCH INSTITUTE   (India)

^b JIWAJI UNIVERSITY   (India)

^c UNIVERSITY OF MILAN   (Italy)

Author keywords

Gluconeogenesis; Hepatic steatosis; High fructose diet; Insulin resistance; NAFLD; Rosiglitazone; Type 2 diabetes

Indexed keywords

ENZYME; FATTY ACID; FATTY ACID SYNTHASE; FRUCTOSE; GLUCOSE; GLUCOSE 6 PHOSPHATASE; HEMOGLOBIN A1C; INSULIN; PHOSPHOENOLPYRUVATE CARBOXYKINASE (GTP); PYRUVIC ACID; ROSIGLITAZONE; STEROL REGULATORY ELEMENT BINDING PROTEIN 1; TRANSCRIPTION FACTOR;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CARBOHYDRATE DIET; CARBOHYDRATE INTAKE; CONTROLLED STUDY; GENE EXPRESSION; GENETIC TRANSCRIPTION; GENOMICS; GLUCONEOGENESIS; GLUCOSE INTOLERANCE; GLUCOSE METABOLISM; GLUCOSE TOLERANCE TEST; GLYCOGEN SYNTHESIS; GLYCOGENOLYSIS; HEXOSE TRANSPORT; HYPERGLYCEMIA; INSULIN RESISTANCE; INSULIN TOLERANCE TEST; MALE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; RAT;

ANIMALS; EPIGENESIS, GENETIC; FATTY LIVER; FRUCTOSE; GLUCONEOGENESIS; GLUCOSE METABOLISM DISORDERS; GLYCOGEN; HYPOGLYCEMIC AGENTS; MALE; RATS; SWEETENING AGENTS; THIAZOLIDINEDIONES;

EID: 67349272292     PISSN: 15908658     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.dld.2008.11.012     Document Type: Article

References (36)

1. Amarapurkar D., Kamani P., Patel N., Gupte P., Kumar P., Agal S., et al. Prevalence of non-alcoholic fatty liver disease: population based study. Ann Hepatol 6 (2007) 161-163
2. Angulo P. NAFLD, obesity, and bariatric surgery. Gastroenterology 130 (2006) 1848-1852
3. Zimmer P., Albert K.G., and Shaw J. Global and societal implications of the diabetes epidemic. Nature 414 (2001) 782-787
4. Bellentani S., Dalle Grave R., Suppini A., Marchesini G., and Fatty Liver Italian Network. Behavior therapy for nonalcoholic fatty liver disease: the need for a multidisciplinary approach. Hepatology 47 (2008) 746-754
5. Gross L.S., Li L., Ford E.S., and Lui S. Increased consumption of refined carbohydrates and the epidemic of type 2 diabetes in the United States: an ecological assessment. Am J Clin Nutr 79 (2004) 774-779
6. Ouyang X., Cirillo P., Sautin Y., McCall S., Bruchette J.L., Diehl A.M., et al. Fructose consumption as a risk factor for non-alcoholic fatty liver disease. J Hepatol 48 (2008) 993-999
7. Braciano H., Lisa F., and Adeli K. Fructose, insulin resistance and metabolic dyslipidemia. Nutr Metab 2 (2005) 1-14
8. Pilkis S.J., and Granner D.K. Molecular physiology of the regulation of hepatic gluconeogenesis and glycolysis. Annu Rev Physiol 54 (1992) 885-909
9. Yoon J.C., Puigserver P., Chen G., Donovan J., Wu Z., Rhee J., et al. Control of hepatic gluconeogenesis through the transcriptional co-activator PGC-1. Nature 413 (2001) 131-138
10. Oakes N.D., Cooney G.J., Cammilleri S., Chisholm D.J., and Kraegen E.W. Mechanisms of liver and muscle insulin resistance induced by chronic high fat feeding. Diabetes 46 (1997) 1768-1774
11. Kao P.C., Wu T.J., Ho L.L.T., and Li X.J. Review: current and new approaches in the management of diabetes mellitus. Ann Clin Lab Sci 30 (2000) 339-345
12. Pereira S., Veeraraghavan P., Ghosh S., and Gandhi M. Animal experimentation and ethics in India: the CPCSEA makes a difference. ATLA (Fourth World Cong) 32 (2004) 411-415
13. Vander-Vries J. Two methods for the determination of glycogen in liver. Biochem J 57 (1954) 410-416
14. Itaya K., and Ui M. Colorimetric determination of free fatty acids in biological fluids. J Lipid Res 6 (1965) 16-20
15. Folch J., Lees M., and Sloane-Stanley G.H. A simple method for the isolation and purification of total lipids from animal tissues. J Biol Chem 226 (1957) 497-506
16. Marone M., Mozzetti S., De Ritis D., Pierelli L., and Scambia G. Semiquantitative RT-PCR analysis to assess the expression levels of multiple transcripts from the same sample. Biol Proc Online 3 (2001) 19-25
17. Lowry O.H., Rosebrough N.J., Forry A.L., and Randall R.J. Protein measurement with folin phenol reagent. J Biol Chem 193 (1951) 265-275
18. Gerhardt C.M., and Klingensmith G.J. New-onset diabetes in an obese adolescent: diagnostic dilemmas. Nat Clin Pract Endocrinol Metab 4 (2008) 578-583
19. Rhodes C.J., and White M.F. Molecular insight into insulin action and secretion. Eur J Clin Invest 32 (2002) 3-13
20. Wahren J., and Ekberg K. Splanchnic regulation of glucose production. Annu Rev Nutr 27 (2007) 329-345
21. Hundal R.S., Krassak M., Dufour S., Laurent D., Lebon V., Chandramouli V., et al. Mechanism by which metformin reduces glucose production in type 2 diabetes. Diabetes 49 (2000) 2063-2069
22. Paquot N., Schneiter P., Jequier E., Gaillard R., Lefebvre P.J., Scheen A., et al. Effects of ingested fructose and infused glucagon on endogenous glucose production in obese NIDDM patients, obese non-diabetic subjects, and healthy subjects. Diabetologia 39 (1996) 580-586
23. Rajasekar P., and Anuradha C.V. Fructose induced gluconeogenesis: effect of l-carnitine. Life Sci 80 (2007) 1176-1183
24. Koo H.Y., Walling M.A., Chung B.H., Nara T.Y., Cho B.H.S., and Nakamura M.T. Dietary fructose induces a wide range of genes with distinct shift in carbohydrate and lipid metabolism in fed and fated rats. Biochem Biophys Acta 1782 (2008) 341-348
25. Youn J.H., Kaslow H.R., and Bergman R.N. Fructose effect to suppress hepatic glycogen degradation. J Biol Chem 262 (1987) 11470-11477
26. Mayes P.A. Intermediary metabolism of fructose. Am J Clin Nutr 58 (1993) 754S-765S
27. Comert B., Mas M.R., Erdem H., Dinc A., Saglamkaya U., Cigerim M., et al. Insulin resistance in non-alcoholic steatohepatitis. Dig Liver Dis 33 (2001) 353-358
28. Puigserver P., and Speigelmen B.M. Peroxisome proliferators-activated receptor-γ co-activator 1α (PGC-1α): transcriptional coactivator and metabolic regulator. Endocrin Rev 24 (2003) 78-90
29. Chawla A., Schwarz E.J., Dimaculangan D.D., and Lazar M.A. Peroxisome proliferator-activated receptor (PPAR) gamma: adipose predominant expression and induction in early adipocyte differentiation. Endocrinology 135 (1994) 798-800
30. Hauner H. The mode of action of thiazolidiaediones. Diabetes Metab Res Rev 18 (2002) S10-S15
31. Yadav H., Jain S., Prasad G.B.K.S., and Yadav M. Preventive effect of Diabegon; a polyherbal preparation during progression of diabetes induced in high fructose fed rats. J Pharmacol Sci 105 (2007) 12-21
32. Herzig S., Long F., Jhala U.S., Hedrick S., Quinn R., Baur A., et al. CREB regulates hepatic gluconeogenesis through the co-activator PGC-1. Nature 413 (2001) 179-183
33. Puigserver P., Adelmant G., Wu Z., Fan M., Xu J., O'Malley B., et al. Activation of PPAR co-activator-1 through transcription factor docking. Science 286 (1999) 1368-1371
34. Daitoku H., Yamagata K., Matsuzaki H., Hatta M., and Fukamizu A. Regulation of PGC-1 promoter activity by protein kinase B and the forkhead transcription factor FKHR. Diabetes 52 (2003) 642-649
35. AOAC. Official methods of analysis. 11th ed. (1970), Association of Official Analytical Chemists, AOAC Washington, DC pp. 536, 858
36. Gopalan C., Rama Shastri B.V., and Balasubramaniam S.C. Nutritive value of Indian foods (1971), National Institute of Nutrition (ICMR), Hyderabad, India