Exploring the wound healing activity of Arnebia densiflora (Nordm.) Ledeb. by in vivo models

Journal of Ethnopharmacology

Volumn 124, Issue 1, 2009, Pages 137-141

  Akkol, Esra Küpeli ^a   Koca, Ufuk ^a   Peşin, Ipek ^a   Yilmazer, Demet ^b   Toker, Gülnur ^a   Yeşilada, Erdem ^c  

^a GAZI UNIVERSITY   (Turkey)

^b DISKAPI YILDIRIM BEYAZIT TRAINING AND RESEARCH HOSPITAL   (Turkey)

^c YEDITEPE UNIVERSITY   (Turkey)

Author keywords

Arnebia densiflora; Boraginaceae; Excision; Incision; Tensiometer; Wound healing

Indexed keywords

ACETIC ACID ETHYL ESTER; ARNEBIA DENSIFLORA EXTRACT; ASIATICOSIDE; CHLOROFORM; HERBACEOUS AGENT; HEXANE; METHANOL; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARNEBIA DENSIFLORA; ARTICLE; BORAGINACEAE; CONTROLLED STUDY; HISTOPATHOLOGY; IN VIVO STUDY; MALE; MOUSE; NONHUMAN; OINTMENT; PLANT ROOT; RAT; SKIN INJURY; SOLVENT EXTRACTION; TREATMENT OUTCOME; WOUND HEALING;

ANIMALS; ANTI-INFECTIVE AGENTS; BORAGINACEAE; DISEASE MODELS, ANIMAL; MALE; MICE; OINTMENTS; PHYTOTHERAPY; PLANT BARK; PLANT EXTRACTS; PLANT ROOTS; RATS; SKIN; TRITERPENES; WOUND HEALING; WOUNDS AND INJURIES;

ARNEBIA; BORAGINACEAE; MUS; RATTUS;

EID: 67349262325     PISSN: 03788741     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jep.2009.03.019     Document Type: Article

References (31)

1. Assimopoulou A.N., Boskou D., and Papageorgiou V.P. Antioxidant activities of alkannin, shikonin and Alkanna tinctoria root extracts in oil substrates. Food Chemistry 87 (2004) 433-438
2. Baser, K.H.C., Honda, G., Miki, W., 1986. Herb Drugs and Herbalists in Turkey, Studia Culturae Islamicae, Tokyo, No. 27.
3. Bozan B., Baser K.H.C., and Kara S. Quantitative determination of naphthaquinones of Arnebia densiflora (Nordm.) Ledeb. by an improved high-performance liquid chromatographic method. Journal of Chromatography A 782 (1997) 133-136
4. Bozan B., Baser K.H.C., and Karab S. Quantitative determination of naphthoquinones of Arnebia densiflora by TLC-densitometry. Fitoterapia 70 (1999) 402-406
5. Chen X., Yang L., Zhang N., Turpin J.A., Buckheit R.W., Osterling C., Oppenheim J.J., and Howard O.M. Shikonin, a component of Chinese herbal medicine, inhibits chemokine receptor function and suppresses human immunodeficiency virus type 1. Antimicrobial Agents and Chemotherapeutics 47 (2003) 2810-2816
6. Ehrlich H.P., and Hunt T.K. The effect of cortisone and anabolic steroids on the tensile strength of healing wounds. Annal Surgery 57 (1968) 117
7. Hu Y., Jiang Z., Leung K.S.Y., and Zhao Z. Simultaneous determination of naphtaquinone derivatives in Boraginaceous herbs by high-performance liquid chromatography. Analytica Chimica Acta 577 (2006) 26-31
8. Kaith B.S., Kaith N.S., and Chauhan N.S. Anti-inflammatory effect of Arnebia euchroma root extracts in rats. Journal of Ethnopharmacology 55 (1996) 77-80
9. Kapadia G.J., Balasubramanian V., Tokuda H., Konoshima T., Takasaki M., Koyama J., Tagahaya K., and Nishino H. Anti-tumor promoting effects of naphthoquinone derivatives on short term Epstein-Barr early antigen activation assay and in mouse skin carcinogenesis. Cancer Letters 113 (1997) 47-53
10. Khajuria R.K., and Jain S.M. Two new naphthoquinones from the roots of Onosma hispidum. Indian Journal of Chemistry B 32 (1993) 390-391
11. Ki{dotless}ri{dotless}mer N., Bozan B., and Baser K.H.C. A new naphthaquinone from the roots of Arnebia densiflora. Fitoterapia 66 (1995) 499-500
12. Ki{dotless}ri{dotless}mer N., Cingi M.I., Alpan S., Gez S., Bozan B., and Baser K.H.C. Investigation of Arnebia densiflora for its toxicity and pharmacological effects. Proceedings of IXth Meeting on Vegetable Crude Drugs. Anadolu University, Faculty of Pharmacy, May 16-19, Eskişehir (Turkey) (1991)
13. Lodhi S., Pawar R.S., Jain A.P., and Singhai A.K. Wound healing potential of Tephrosia purpurea (Linn.) Pers. in rats. Journal of Ethnopharmacology 108 (2006) 204-210
14. Masuda Y., Shima G., Aiuchi T., Horie M., Hori K., Nakajo S., Kajimoto S., Shibayama-Imazu T., and Nakaya K. Involvement of tumor necrosis factor receptor-associated protein 1 (TRAP1) in apoptosis induced by β-hydroxyisovalerylshikonin. Journal of Biological Chemistry 279 (2004) 42503-42515
15. Ozaki Y., Ohno A., Abe K., Saito Y., and Satake M. Comparative study on the accelerative effect of koushikon and nanshikon and their constituents on proliferation of granuloma tissue in rats. Biological and Pharmaceutical Bulletin 16 (1993) 683-685
16. Ozaki Y., Xing L., and Satake M. Accelerative effect of nanshikon and its constituents on the proliferation of granulation tissue in rats. Biological and Pharmaceutical Bulletin 19 (1996) 233-236
17. Papageorgiou V.P. Wound healing properties of naphtaquinone pigments from Alkanna tinctoria. Experientia 34 (1978) 1499-1501
18. Papageorgiou V.P., Assimopoulou A.N., Couladouros E.A., Hepworth D., and Nicolaou K.C. The chemistry and biology of alkannin, shikonin and related naphthazarin natural products. Angewandte Chemie 38 (1999) 270-300
19. Sadaf F., Saleem R., Ahmed M., Ahmad S.I., and Navaid-ul Z. Healing potential of cream containing extract of Sphaeranthus indicius on dermal wounds in Guinea pigs. Journal of Ethnopharmacology 107 (2006) 161-163
20. Sasaki K., Abe H., and Yoshizaki F. In vitro antifungal activity of naphthoquinone derivatives. Biological and Pharmaceutical Bulletin 25 (2002) 669-670
21. Sasaki K., Yoshizaki F., and Abe H. The anti-candida activity of shikon. Yakugaku Zasshi 120 (2000) 587-589
22. Sekine T., Masumizu T., Maitani Y., and Nagai T. Evaluation of superoxide anion radical scavenging activity of shikonin by electron spin resonance. International Journal of Pharmaceutics 174 (1998) 133-139
23. Senel O., Cetinkale O., Ozbay G., Ahcioglu F., and Bulan R. Oxygen free radicals impair wound healing in ischemic rat skin. Annals of Plastic Surgery 39 (1997) 516-523
24. Shen C.C., Syu W.J., Li S.Y., Lin C.H., Lee G.H., and Sun C.M. Antimicrobial activities of naphthazarins from Arnebia euchroma. Journal of Natural Products 65 (2002) 1857-1862
25. Sidhu G.S., Singh A.K., Banaudha K.K., Gaddipati J.P., Patnaik G.K., and Maheshwari R.K. Arnebin-1 accelerates normal and hydrocortisone-induced impaired wound healing. The Journal for Investigative Dermatolology 113 (1999) 773-781
26. Suguna L., Singh S., Sivakumar P., Sampath P., and Chandrakasan G. Influence of Terminalia chebula on dermal wound healing in rats. Phytotherapy Research 16 (2002) 227-231
27. Tanaka S., Mayumi T., Tsukada M., and Tabuta M. A comparative study an anti-inflammatory activities of enantiomers shikonin and alkannin. Journal of Natural Products 49 (1986) 466-469
28. Tramontina V.A., Machado M.A., Nogueira Filho Gda R., Kim S.H., Vizzioli M.R., and Toledo S. Effect of bismuth subgallate (local hemostatic agent) on wound healing in rats. Histological and histometric findings. Brazilian Dental Journal 13 (2002) 11-16
29. Wang W.J., Bai J.Y., Liu D.P., Xue L.M., and Zhu X.Y. The antiinflammatory activity of shikonin and its inhibitory effect on leukotriene B4 biosynthesis. Yao Xue Xue Bao (Acta Pharmaceutica Sinica) 29 (1994) 161-165
30. Yamasaki K., Otake T., Mori H., Morimoto M., Ueba N., Kurokawa Y., Shiota K., and Yuge T. Screening test of crude drug extract on anti-HIV activity. Yakugaku Zasshi 113 (1993) 818-824
31. Yesilada E., Sezik E., Aslan M., and Yesilada A. Quantitative analysis of the enantiomeric naphthaquinone derivatives from Boraginaceous roots by high performance liquid chromatography. Journal of Liquid Chromatography and Related Technologies 19 (1996) 3369-3381