Th1-type epitopes-based cocktail PDDV attenuates hepatic fibrosis in C57BL/6 mice with chronic Schistosoma japonicum infection

Vaccine

Volumn 27, Issue 31, 2009, Pages 4110-4117

  Tao, Fang Fang ^a,b   Yang, Yan Fen ^a   Wang, Hui ^a   Sun, Xin Juan ^a   Luo, Jie ^a   Zhu, Xiang ^a   Liu, Feng ^a   Wang, Yong ^a   Su, Chuan ^a   Wu, Hai Wei ^a   Zhang, Zhao Song ^a  

^a NANJING MEDICAL UNIVERSITY   (China)

^b ZHEJIANG CHINESE MEDICAL UNIVERSITY   (China)

Author keywords

Cocktail PDDV; Hepatic fibrosis; Schistosoma japonicum; Th1 type epitope

Indexed keywords

ALANYLISOLEUCYLALANYLARGINYLPHENYLALANYLISOLEUCYLALANYLARGINYLLYSYLHISTIDYLASPAR AGINYLMETHIONYLMETHIONYLGLYCINE; ALPHA SMOOTH MUSCLE ACTIN; ARGINYLLYSYLTRYPTOPHYLPHENYLALANYLLYSYLTHREONYLASPARAGINYLTHREONYLPROLYLSERINE; COLLAGEN TYPE 1; COLLAGEN TYPE 3; CPG OLIGODEOXYNUCLEOTIDE; CYTOKINE; DNA VACCINE; EPITOPE; GAMMA INTERFERON; GELATINASE B; IMMUNOLOGICAL ADJUVANT; INTERLEUKIN 13; INTERLEUKIN 4; ISOLEUCYLTHREONYLGLUTAMYLLEUCYLGLUTAMYLASPARTYLVALYLALANYLGLUTAMYLARGINYLGLUTAMY LARGINYLLEUCYLLYSYLALANINE; MESSENGER RNA; PLASMID DNA; PRAZIQUANTEL; PROLYLLEUCYLISOLEUCYLGLUTAMINYLISOLEUCYLISOLEUCYLALANYLALANYLTHREONYLMETHIONYLSE RYLLYSYLALANYLLYSINE; RECOMBINANT DNA; TISSUE INHIBITOR OF METALLOPROTEINASE 1; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; C57BL 6 MOUSE; CELL ACTIVATION; CONTROLLED STUDY; DRUG MIXTURE; EXTRACELLULAR MATRIX; FEMALE; HISTOPATHOLOGY; IMMUNE RESPONSE; LIVER; LIVER FIBROSIS; LYMPHOCYTE PROLIFERATION; MONONUCLEAR CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SCHISTOSOMA JAPONICUM; SCHISTOSOMIASIS JAPONICA; SPLEEN; STELLATE CELL; TH1 CELL; TH2 CELL; UPREGULATION;

ACTINS; ADJUVANTS, IMMUNOLOGIC; ANIMALS; DNA; EPITOPES, T-LYMPHOCYTE; FEMALE; HUMANS; INTERFERON-GAMMA; INTERLEUKIN-13; INTERLEUKIN-4; LIVER CIRRHOSIS; MATRIX METALLOPROTEINASE 9; MICE; MICE, INBRED C57BL; PROTOZOAN VACCINES; SCHISTOSOMA JAPONICUM; SCHISTOSOMIASIS JAPONICA; TH1 CELLS; TISSUE INHIBITOR OF METALLOPROTEINASE-1; VACCINES, DNA;

EID: 67349255280     PISSN: 0264410X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.vaccine.2009.04.073     Document Type: Article

References (34)

1. McManus D.P., and Loukas A. Current status of vaccines for schistosomiasis. Clin Microbiol Rev 21 1 (2008) 225-242
2. Weng H.L., Wang B.E., Jia J.D., Wu W.F., Xian J.Z., Mertens P.R., et al. Effect of interferon-gamma on hepatic fibrosis in chronic hepatitis B virus infection: a randomized controlled study. Clin Gastroenterol Hepatol 3 8 (2005) 819-828
3. Gattoni A., Parlato A., Vangieri B., Bresciani M., and Derna R. Interferon-gamma: biologic functions and HCV terapy (type I/II) (2 of 2 parts). Clin Ter 157 5 (2006) 457-468
4. Baroni G.S., D'Ambrosio L., Curto P., Casini A., Mancini R., Jezequel A.M., et al. Interferon gamma decreases hepatic stellate cell activation and extracellular matrix deposition in rat liver fibrosis. Hepatology 23 5 (1996) 1189-1199
5. Wynn T.A. Development of an antipathology vaccine for schistosomiasis. Ann N Y Acad Sci 797 (1996) 191-195
6. Hemmann S., Graf J., Roderfeld M., and Roeb E. Expression of MMPs and TIMPs in liver fibrosis - a systematic review with special emphasis on anti-fibrotic strategies. J Hepatol 46 5 (2007) 955-975
7. Friedman S.L. Liver fibrosis-from bench to bedside. J Hepatol 38 Suppl 1 (2003) S38-53
8. Iredale J.P. Cirrhosis: new research provides a basis for rational and targeted treatments. BMJ 327 7407 (2003) 143-147
9. Van den Steen P.E., Dubois B., Nelissen I., Rudd P.M., Dwek R.A., and Opdenakker G. Biochemistry and molecular biology of gelatinase B or matrix metalloproteinase-9 (MMP-9). Crit Rev Biochem Mol Biol 37 6 (2002) 375-536
10. Zhang Y., Taylor M.G., Johansen M.V., and Bickle Q.D. Vaccination of mice with a cocktail DNA vaccine induces a Th1-type immune response and partial protection against Schistosoma japonicum infection. Vaccine 20 5-6 (2001) 724-730
11. Li G.F., Wang Y., Zhang Z.S., Wang X.J., Ji M.J., Zhu X., et al. Identification of immunodominant Th1-type T cell epitopes from Schistosoma japonicum 28 kDa glutathione-S-transferase, a vaccine candidate. Acta Biochim Biophys Sin (Shanghai) 37 11 (2005) 751-758
12. Tao F.F., Wang X.J., Liu F., Wang H., Sun X.J., Wang Y., et al. Immunological identification of Th1-type epitope in the triose-phosphate isomerase of Schistosoma japonicum. J Pathog Biol 3 4 (2008) 266-271
13. Tao F.F., Wang H., Sun X.J., Liu F., Wang Y., Su C., et al. Immunological identification of a synthetic peptide from the paramyosin of Schistosoma japonicum. Chin J Parasitol Parasitic Dis 27 1 (2009) 31-34
14. Li G.F., Zhang Z.S., Zhu H.F., Wang Y., Zhu X., Wang X.J., et al. Selection of CpG ODN and its adjuvant effect on antigen rSj28GST. Chin J Schistosomiasis Control 16 (2004) 104-108
15. Liu L., Zhou X., Liu H., Xiang L., and Yuan Z. CpG motif acts as a 'danger signal' and provides a T helper type 1-biased microenvironment for DNA vaccination. Immunology 115 2 (2005) 223-230
16. Zhang L., Yang X., Yang Y., Zhao J., Yang J., Liu F., et al. Characterization of a partially protective B-cell epitope within the 62 kDa antigen of Schistosoma japonicum. Acta Biochim Biophys Sin (Shanghai) 39 10 (2007) 770-778
17. Zhang L., Yang Y., Yang X., Zhao J., Yang J., Liu F., et al. T cell epitope-based peptide-DNA dual vaccine induces protective immunity against Schistosoma japonicum infection in C57BL/6J mice. Microbes Infect 10 3 (2008) 251-259
18. Liu G., Molas M., Grossmann G.A., Pasumarthy M., Perales J.C., Cooper M.J., et al. Biological properties of poly-l-lysine-DNA complexes generated by cooperative binding of the polycation. J Biol Chem 276 37 (2001) 34379-34387
19. Scheuer P.J. Classification of chronic viral hepatitis: a need for reassessment. J Hepatol 13 3 (1991) 372-374
20. Ebrahimkhani M.R., Kiani S., Oakley F., Kendall T., Shariftabrizi A., Tavangar S.M., et al. Naltrexone, an opioid receptor antagonist, attenuates liver fibrosis in bile duct ligated rats. Gut 55 11 (2006) 1606-1616
21. Weng H.L., Cai W.M., and Liu R.H. Animal experiment and clinical study of effect of gamma-interferon on hepatic fibrosis. World J Gastroenterol 7 1 (2001) 42-48
22. Yang Y., Cai W., and Jin G. Dynamic changes in hepatic myofibroblast of rabbits with Schistosoma japonicum. Zhonghua Yi Xue Za Zhi 79 11 (1999) 870-873
23. Hurtado C.A., and Rachubinski R.A. Isolation and characterization of YlBEM1, a gene required for cell polarization and differentiation in the dimorphic yeast Yarrowia lipolytica. Eukaryot Cell 1 4 (2002) 526-537
24. De Smedt S.C., Demeester J., and Hennink W.E. Cationic polymer based gene delivery systems. Pharm Res 17 2 (2000) 113-126
25. Fabre J.W., and Collins L. Synthetic peptides as non-viral DNA vectors. Curr Gene Ther 6 4 (2006) 459-480
26. Liu H.L., Wu Y.Z., Zhao J.P., Ni B., Jia Z.C., Zhou W., et al. Effective elicitation of anti-tumor immunity by collocation of antigen with encoding gene in the same vaccine. Immunol Lett 89 2-3 (2003) 167-173
27. Wu Y.Z., Zhao J.P., Wan Y., Jia Z.C., Zhou W., Bian J., et al. Mimovirus: a novel form of vaccine that induces hepatitis B virus-specific cytotoxic T-lymphocyte responses in vivo. J Virol 76 20 (2002) 10264-10269
28. Aral C., and Akbuga J. Preparation and in vitro transfection efficiency of chitosan microspheres containing plasmid DNA:poly(l-lysine) complexes. J Pharm Pharm Sci 6 3 (2003) 321-326
29. Breuzard G., Tertil M., Goncalves C., Cheradame H., Geguan P., Pichon C., et al. Nuclear delivery of NFkappaB-assisted DNA/polymer complexes: plasmid DNA quantitation by confocal laser scanning microscopy and evidence of nuclear polyplexes by FRET imaging. Nucleic Acids Res 36 12 (2008) e71
30. Gamvrellis A., Leong D., Hanley J.C., Xiang S.D., Mottram P., and Plebanski M. Vaccines that facilitate antigen entry into dendritic cells. Immunol Cell Biol 82 5 (2004) 506-516
31. Chen J.X., Liu S.X., Cao J.P., Song G.C., and Xu Y.X. Anti-schistosomiasis effect induced by full length DNA vaccine coding paramyosin of Schistosoma japonicum in C57BL/6 mice. Chin J Parasitol Parasitic Dis 24 2 (2006) 81-86
32. Bartley P.B., Ramm G.A., Jones M.K., Ruddell R.G., Li Y., and McManus D.P. A contributory role for activated hepatic stellate cells in the dynamics of Schistosoma japonicum egg-induced fibrosis. Int J Parasitol 36 9 (2006) 993-1001
33. Fujita T., Maesawa C., Oikawa K., Nitta H., Wakabayashi G., and Masuda T. Interferon-gamma down-regulates expression of tumor necrosis factor-alpha converting enzyme/a disintegrin and metalloproteinase 17 in activated hepatic stellate cells of rats. Int J Mol Med 17 4 (2006) 605-616
34. Radaeva S., Sun R., Jaruga B., Nguyen V.T., Tian Z., and Gao B. Natural killer cells ameliorate liver fibrosis by killing activated stellate cells in NKG2D-dependent and tumor necrosis factor-related apoptosis-inducing ligand-dependent manners. Gastroenterology 130 2 (2006) 435-452